Moxifloxacin Hydrochloride 98% ligh yellow powder with CAS 186826-86-8

Moxifloxacin Hydrochloride

CAS#	186826-86-8
Appearance	ligh yellow powder
Specific Rotation	-125°~ -138°
Isomer	not more than 0.10%
Heavy Metal	not more than 20ppm
Water	not more than 4.5%
Assay	98.0%-102.0%

Introduction of Moxifloxacin HCL

Moxifloxacin hydrochloride is a drug for treating adults with upper and lower respiratory tract infections,
such as acute sinusitis, acute attack of chronic bronchitis, community-acquired pneumonia, and skin and
soft tissue infections.

The antibacterial mechanism of 8-fluoroquinolones is broad-spectrum antibacterial activity. Moxifloxacin
showed broad-spectrum antibacterial activity against Gram-positive bacteria, Gram-negative bacteria,
anaerobic bacteria, acid fast bacteria and atypical microorganisms such as Mycoplasma, chlamydia
and Legionella in vitro. The antibacterial mechanism is to interfere with II and IV topoisomerase.
Topoisomerase is a key enzyme controlling DNA topology and in DNA replication, repair and transcription.
The bactericidal curve showed that moxifloxacin had concentration dependent bactericidal activity. The
minimum bactericidal concentration and minimum inhibitory concentration were basically the same.
Moxifloxacin is also effective against bacteria resistant to b-lactams and macrolides. The experimenta
l animal model of infection confirmed that moxifloxacin had high activity in vivo.

Functions:

* Treatment of the upper and lower respiratory infection