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Factory Fast Delivery Bupivacaine Powder CAS 2180-92-9 with Good Price

Name: Factory Fast Delivery Bupivacaine Powder CAS 2180-92-9 with Good Price
Brand: XAZB
SKU: pr2205203739
Availability: InStock

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CAS No.:

2180-92-9

Grade:

Pharmaceutical Grade

Content:

99%

Brand:

XAZB

Packaging:

Foil Bag

Sample Available:

Yes

Price valid (until):

2022-12-31

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Xian ZB Biotech Co.,Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents

Average Lead Time:

8 days

Qualification:

Main Products:

Herb Extracts,Cosmetic raw materails,API

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Product Description
Seller Information

Description

Factory Fast Delivery Bupivacaine Powder CAS 2180-92-9 with Good Price

Bupivacaine is an amide-type, long-acting local anesthetic. Bupivacaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.

Factory Fast Delivery Bupivacaine Powder CAS 2180-92-9 with Good Price

_{Bupivacaine is an anesthetic (numbing medicine) that is used as a local (in only one area) anesthetic.

Bupivacaine is given as an epidural injection into the spinal column to produce numbness during labor, surgery, or certain medical procedures.

Bupivacaine is also used as an anesthetic for dental procedures.

Bupivacaine may also be used for purposes not listed in this medication guide.}

ECHEMI Editorial Reference

Solid
ChEBI: 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide is a piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline. It is a piperidinecarboxamide, an aromatic amide and a tertiary amino compound. It is a conjugate base of a 1-butyl-2-[(2,6-dimethylphenyl)carbamoyl]piperidinium.
Bupivacaine was synthesized simultaneously with mepivacainein 1957 but was at first overlooked because of the increasedtoxicity compared with mepivacaine. When themethyl on the cyclic amine of mepivacaine is exchanged fora butyl group the lipophilicity, potency and the duration ofaction all increase. Literature reports of cardiovascular toxicity,including severe hypotension and bradycardia, areabundant in the literature.91 Bupivacaine is highly bound toplasma proteins (95%), and thus the free concentration mayremain low until all of the protein binding sites are occupied.After that point, the plasma levels of bupivacaine rise rapidlyand patients may progress to overt cardiac toxicity withoutever showing signs of CNS toxicity. The cardiotoxicity ofbupivacaine is a result of its affinity to cardiac tissues and itsability to depress electrical conduction and predispose theheart to reentry types of arrhythmias. The cardiotoxicity ofbupivacaine was found to be significantly more prominentwith the “R” isomer, or the racemic mixture, thus the “S”stereoisomer is now on the market as levobupivacaine.

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Basic Info

Product Name:

Bupivacaine

Other Name:

MARCAINE;BUPIVACAINE;BUPIVACAINE BASE;2',6'-Pipecoloxylidide, 1-butyl-;6’-pipecoloxylidide,1-butyl-2;Anekain;Carbostesin;DL-Bupivacaine

CAS No.:

2180-92-9

Molecular Formula:

C18H28N2O

InChIKeys:

LEBVLXFERQHONN-UHFFFAOYSA-N

Molecular Weight:

288.43

Exact Mass:

288.43

EC Number:

218-553-3

Categories:

Anesthetic Agents

Characteristics

PSA:

32.3

XLogP3:

3.6

Appearance:

Solid

Density:

1.0238 (rough estimate)

Melting Point:

107.5-108°

Boiling Point:

430.65°C (rough estimate)

Flash Point:

209.9±28.7 °C

Refractive Index:

1.5700 (estimate)

Water Solubility:

101.5mg/L(25 ºC)

Storage Conditions:

Bupivacaine hydrochloride solutions should be stored between 15-30 deg C and freezing should be avoided; solutions containing epinephrine should be protected from light.

Vapor Pressure:

1.31X10-7 mm Hg at 25 deg C (est)

Toxicity:

Highly toxic

Flammability characteristics:

Thermal decomposition to emit toxic nitrogen oxide fumes

PKA:

8.09; also reported as 8.17(at 25℃)

See More Bupivacaine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 2, Oral

Acute toxicity - Category 1, Dermal

Skin irritation, Category 2

Serious eye damage, Category 1

Acute toxicity - Category 2, Inhalation

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H300 Fatal if swallowed H310 Fatal in contact with skin H315 Causes skin irritation H318 Causes serious eye damage H330 Fatal if inhaled
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label).
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity. Bupivacaine hydrochloride

See More Bupivacaine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Herb Extracts,Cosmetic raw materails,API

Location:
1403,Jinye B Block

Payment Terms:
TT against copy of documents

Average lead Time:
8 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2015

Xian ZB Biotech Co.,Ltd is a leading Manufactory supplier of Arbutin, Nicotinamide, Flucytosine based in Xi'an, Shaanxi, China. With a commitment to quality and customer satisfaction, Xian ZB Biotech Co.,Ltd has become a trusted name in the industry. Our product line includes a range of high-quality Arbutin, Nicotinamide, Flucytosine, which are available at competitive prices. Xian ZB Biotech Co.,Ltd has established itself as a reliable supplier of chemical products on the echemi.com.
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Factory Fast Delivery Bupivacaine Powder CAS 2180-92-9 with Good Price

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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