Phenolphthalein Powder CAS 77-09-8
GMP ISO 1 Inquiries
77-09-8
99%
XAZB
Foil Bag, Drum
Yes
2022-12-31
Herb Extracts,Cosmetic raw materails,API
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Product Description
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Seller Information
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Inquiry History
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Description
Product DescriptionPhenolphthalein is a chemical that is commonly used as a colorimetric pH indicator. The compound has been observed to turn orange at pH <0, clear between pH 0-8.2, fuchsia between pH 8.2-12, and clear again at a pH above 12.
It has been postulated that the mutagenic effects of Phenolphthalein at high doses can be attributed the enhancement intracellular free oxygen radicals. The compound has also been observed to induce mitotic abnormalities and micronuclei with kinetochores in vitro.
Product PhotosECHEMI Editorial ReferencePhenolphthalein is a widely applied but toxic indicator dye.
Phenolphthalein appears as white or yellowish-white to pale orange fine crystalline powder. Odorless. Aqueous solution is acidic. Colorless to pH 8.5; pink to deep-red above pH 9. Colorless in presence of large amounts of alkali. Tasteless. (NTP, 1992)
Phenolphthalein appears as white or yellowish-white to pale orange fine crystalline powder. Odorless. Aqueous solution is acidic. Colorless to pH 8.5; pink to deep-red above pH 9. Colorless in presence of large amounts of alkali. Tasteless. (NTP, 1992)|Phenolphthalein is a member of phenols. It derives from a 2-benzofuran-1(3H)-one.|Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.|Phenolphthalein is an organic compound used as a laboratory reagent and pH indicator. Phenolphthalein exerts laxative effects by stimulating the intestinal mucosa and constricting smooth muscles. However, phenolphthalein is no longer used as a laxative due to the suspected carcinogenicity of this compound.|An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.CertificatesBasic Info-
Product Name:
3,3-Bis(4-hydroxyphenyl)phthalide
Other Name:1(3H)-Isobenzofuranone,3,3-bis(4-hydroxyphenyl)-;Phenolphthalein;3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone;3,3-Bis(4-hydroxyphenyl)phthalide;Purga;Laxogen;Spulmako-lax;Lilo;Trilax;Koprol;Purgophen;Euchessina;Phthalimetten;Purgen;Phthalin;3,3-Bis(p-hydroxyphenyl)phthalide;NSC 10464;NSC 215214;TY 9;PX 0520-1;3,3-Bis-(4-hydroxy-phenyl)-3H-isobenzofuran-1-one;3,3-Bis(4-hydroxyphenyl)-2-benzofuran-1-one;467-29-8;57214-20-7;390417-24-0;546094-13-7;1541170-18-6
CAS No.:77-09-8
Molecular Formula:C20H14O4
InChIKeys:InChIKey=KJFMBFZCATUALV-UHFFFAOYSA-N
Molecular Weight:318.32
Exact Mass:318.32
BRN:284423
EC Number:201-004-7
UNII:6QK969R2IF
NSC Number:757271|215214|10464
UN Number:1993
DSSTox ID:DTXSID0021125
NCI Thesaurus Code:C29359
Color/Form:White or yellowish-white minute, triclinic crystals, often twinned|White rhombic needles|Pale yellow powder
ATC Code:A - Alimentary tract and metabolism
HScode:29322910
Categories:
Characteristics-
PSA:
66.8
XLogP3:3.6
Appearance:White to yellow-white Solid
Density:1.277 g/cm3 @ Temp: 32 °C
Melting Point:262.5 °C
Boiling Point:557.8±50.0 °C at 760 mmHg
Flash Point:24 °C
Refractive Index:1.693
Water Solubility:H2O: <0.1 g/100 mL;soluble in alcohol. Slightly soluble in ether. Slightly soluble in dimethyl sulfoxide and insoluble in benzene or hexane.
Storage Conditions:Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ) that bears appropriate label. An inventory should be kept, showing quantity of carcinogen & date it was acquired Facilities for dispensing should be contiguous to storage area.
Vapor Pressure:6.7X10-13 mm Hg @ 25 deg C /Estimated/
Odor:ODORLESS
PKA:9.7(at 25 °C)
Henrys Law Constant:Henry's Law constant = 9.0X10-16 atm-cu m/mol @ 25 °C /Estimated/
Dissociation Constants:9.7 (at 25 °C)|pKa = 9.7 at 25 °C
Collision Cross Section:172.1 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Solutions are colorless to pH 8.5; pink to deep-red, above pH 9|Forms an almost colorless solution in neutral or acid solution, pink to deep red in presence of alkali, but colorless in the presence of large amounts of alkali.|Hydroxyl radical reaction rate constant = 8.4X10-11 cu cm/molecule-sec @ 25 °C /Estimated/
Air and Water Reactions:Insoluble in water.
Reactive Group:Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters
Reactivity Profile:PHENOLPHTHALEIN is incompatible with alkaloids. (NTP, 1992)
Hazard IdentificationClassification of the substance or mixture
Germ cell mutagenicity, Category 2
Carcinogenicity, Category 1B
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H341 Suspected of causing genetic defects
H350 May cause cancer
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. Chemical Carcinogens
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Seller Information
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Business Type:
Manufactory
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Main Products:
Herb Extracts,Cosmetic raw materails,API
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Location:
1403,Jinye B Block
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Payment Terms:
TT against copy of documents
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Average lead Time:
8 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
India
Phenolphthalein
25.00 KG Oct 12, 2025 Post an enquiry for this product
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