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Berberine HCl 95% Yellow Brown powder Arshine

Name: Berberine HCl 95% Yellow Brown powder Arshine
Brand: Arshine
SKU: pr2211251828
Price: 20 USD
Availability: InStock

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CAS No.:

633-65-8

Grade:

Food Grade

Content:

95%

Port:

shanghai

Brand:

Arshine

Packaging:

25kg

Sample Available:

Yes

Price valid (until):

2024-12-31

Contact Supplier

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Arshine Group Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

cosmetic additives,Veterinary APIs,Feed additives,medical and pharmaceutical packaging materials,pharmaceutical equipment,Natural Nutrition Ingredients

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Product Description
Seller Information
Inquiry History

Description

Berberine, or berberine hydrochloride, is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in goldenseal, barberry, Oregon grape, and tree turmeric. It is one of the most effective natural supplements available that might help strengthen the heartbeat, which could benefit people with certain heart conditions.

Product name	BERBERINE HCL
Botanical name	Coptis chinensis
Part of Plant Used	Dried Roots
Product Code	Specifications	Analytical method
	Berberine HCl CP2015	HPLC
*Customized specifications available upon request

Application

1.What Is Berberine HCl?

Berberine is a bioactive compound that can be extracted from several different plants, including a group of shrubs called Coptis chinensis.It has a long history of use in traditional Chinese medicine.

Berberine has been shown to lower blood sugar, cause weight loss and improve heart health, etc. It is one of the few supplements shown to be as effective as a pharmaceutical drug.

2.How Berberine HCl Works

Berberine has now been tested in hundreds of different studies. Berberine affects the body at the molecular level, and has a variety of functions inside cells. One of the main functions is activating an important enzyme called AMPK. This enzyme is sometimes referred to as a “metabolic master switch”. It is found in the cells of various organs, including the brain, muscle, kidney, heart and liver. This enzyme plays a major role in regulating metabolism. AMPK can help regulate how the body uses blood sugar. Researchers believe this activation can help treat diabetes and related health issues, such as obesity and high cholesterol.

3.Benefits and Uses

Lower blood sugar

Lower cholesterol

Prevent recurring UTIs and cystitis

Anti-inflammatory and antimicrobial

May help prevent certain cancers

Storage

Store in dry conditions below 30º C, away from sunlight. After opening, it should be stored in a separate package.

ECHEMI Editorial Reference

Berberine has shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells; MAPK and Wnt/β-catenin pathways affected by Berberine.IC50 value:Target: Anticancer agentThe plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways regulated by this compound is needed to define the mechanism of its action in cancer treatment. In this review, the molecu
Berberine chloride (TN) is an organic molecular entity.|Berberine Chloride is the orally bioavailable, hydrochloride salt form of berberine, a quaternary ammonium salt of an isoquinoline alkaloid and active component of various Chinese herbs, with potential antineoplastic, radiosensitizing, anti-inflammatory, anti-lipidemic and antidiabetic activities. Although the mechanisms of action through which berberine exerts its effects are not yet fully elucidated, upon administration this agent appears to suppress the activation of various proteins and/or modulate the expression of a variety of genes involved in tumorigenesis and inflammation, including, but not limited to transcription factor nuclear factor-kappa B (NF-kB), myeloid cell leukemia 1 (Mcl-1), B-cell lymphoma 2 (Bcl-2), B-cell lymphoma-extra large (Bcl-xl), cyclooxygenase (COX)-2, tumor necrosis factor (TNF), interleukin (IL)-6, IL-12, inducible nitric oxide synthase (iNOS), intercellular adhesion molecule-1 (ICAM-1), E-selectin, monocyte chemoattractant protein-1 (MCP-1), C-X-C motif chemokine 2 (CXCL2), cyclin D1, activator protein (AP-1), hypoxia-inducible factor 1 (HIF-1), signal transducer and activator of transcription 3 (STAT3), peroxisome proliferator-activated receptor (PPAR), arylamine N-acetyltransferase (NAT), and DNA topoisomerase I and II. The modulation of gene expression may induce cell cycle arrest and apoptosis, and inhibit cancer cell proliferation. In addition, berberine modulates lipid and glucose metabolism.

Certificates

Basic Info

Product Name:

Berberine hydrochloride

Other Name:

Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-,chloride (1:1);Berbinium,7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-,chloride;Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-,chloride;Berberine,chloride;Berberine hydrochloride;Berberinium chloride;NSC 646666;NSC 163088;Berberine IR;16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride;1082532-96-4

CAS No.:

633-65-8

Molecular Formula:

C20H18NO4.Cl

InChIKeys:

InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M

Molecular Weight:

371.81400

Exact Mass:

371.09200

EC Number:

211-195-9

UNII:

UOT4O1BYV8

NSC Number:

757795|163088|646666

DSSTox ID:

DTXSID8024602

NCI Thesaurus Code:

C87331

HScode:

3003409000

Categories:

Plant Extracts

Characteristics

PSA:

40.80000

XLogP3:

0.10030

Appearance:

yellow crystalline powder

Density:

1.654g/cm3

Melting Point:

214 °C

Water Solubility:

soluble in cold water

Storage Conditions:

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from

Toxicity:

LD50 orl-rat: >15 g/kg KSRNAM 8,654,74

Collision Cross Section:

175.9 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Berberine hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Berberine hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
cosmetic additives,Veterinary APIs,Feed additives,medical and pharmaceutical packaging materials,pharmaceutical equipment,Natural Nutrition Ingredients

Location:
Factory 401, Building 14, Xinggong Science and Technology Park, No.100 Luyun Road, Changsha High-Tech Development Zone

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
Above $100 million

Total Employees:
201-300

Year of Establishment:
2021

Company Certificates
- FAMI-QS
- AEO
- ISO9001
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Arshine Group Co., Ltd. (Arshine Group for short) was founded in Shenzhen in 2007. Over the decades, Arshine has maintained sound development and rapid global expansion with an average annual growth rate of over 30%. Based on China and looking at the world, the Group has become a first-class and industry-leading professional health industry chain service group in China, with an annual turnover of over $150million.
Arshine Group supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates, pharmaceutical equipment, medical and pharmaceutical packaging materials, medical devices, etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Arshine's marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.
Arshine Group has been highly recognized by all sectors of society since its establishment! Arshine is an AA Grade customer of Sinosure in Hunan Province and an AEO-accredited enterprise of China Customs. It has been certified by ISO9001 and EU FAMI-QS, and has obtained Class III Medical Device Trading Permit. As a member of the Board of Directors of the China Chamber of Commerce for Import & Export of Medicines & Health Products, Arshine has been awarded the title of "Quality Supplier and Partner in the International Market" by the Chamber in recent years. As the best human resource management company in Hunan Province, the Group has been awarded as Employer of the Year for several successive years.
In the future, Arshine Group will expand its business in the health industry, increase investment in R&D and production, and gradually become a trading, service and investment integrated group enterprise with trading business as its core. Arshinees will stay true to the mission of serving the global health industry and helping create a win-win situation.

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
Netherlands	Berberine Hydrochloride	1000 KG	May 12, 2026
India	Berberine hydrochloride	1000 KG	Dec 7, 2023
United States	Berberine HCl 95% Yellow Brown powder Arshine	25 KG	Nov 20, 2023

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