GSK1059615
958852-01-2
99%
2026-07-05
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName GSK1059615 Cat No CEI-0107 Description GSK1059615 CAS No 958852-01-2 Molecular Weight 333.36 Purity >99% Storage 2 years at -20 centigrade Targets PI3K-alpha Molecular Formula C18H11N3O2S Solubility No In vitro As a novel and dual inhibitor, GSK1059615 can inhibit PI3Kalpha, PI3Kbeta, PI3Kdelta, PI3Kgamma and mTOR with IC50 of 0.4 nM, 0.6 nM, 2 nM, 5 nM and 12 nM. In T47D and BT474 cancer cells, GSK1059615 inhibits the phosphorylation of Akt at S473, with IC50 of 40 nM. category Inhibitors(c1514) cas_num 958852-01-2 Basic Info-
Product Name:
5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione
Other Name:5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione;GSK 1059615;(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione;GSK 1059615 SodiuM Salt Hydrate;(5Z)-5-[[4-(4-pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione sodium salt hydrate;GSK-615
CAS No.:958852-01-2
Molecular Formula:C18H11N3O2S
InChIKeys:QDITZBLZQQZVEE-YBEGLDIGSA-N
Molecular Weight:332
Exact Mass:333.057190
Categories:
Characteristics-
PSA:
97.2
XLogP3:1.78
Appearance:yellow
Density:1.4±0.1 g/cm3
Refractive Index:1.759
Water Solubility:H2O: ≥8mg/mL
Storage Conditions:Store at +4°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product