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Cytarabine

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CAS No.:

147-94-4

Content:

99%

Price valid (until):

2026-06-30

Company Type:
Manufactory
Location:
United States
Qualification:
Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

  • Product Description

  • Seller Information

  • Inquiry History

  • Description
    ProductNameCytarabine
    Cat NoCEI-0319
    DescriptionCytarabine
    CAS No147-94-4
    Molecular Weight243.22
    Purity>99%
    Storage2 years at -20centigrade Powder
    TargetsDNA synthesis
    Molecular FormulaC9H13N3O5
    SolubilityDMSO 1 mg/mL, Water 48 mg/mL, Ethanol
    In vitroCytarabine (AraC) is phosphorylated into a triphosphate form (Ara-CTP) involving deoxycytidine kinase (dCK), which competes with dCTP for incorporation into DNA, and then blocks DNA synthesis by inhibiting the function of DNA and RNA polymerases. Cytarabine displays a higher growth inhibitory activity towards wild-type CCRF-CEM cells compared to other acute myelogenous leukemia (AML) cells with IC50 of 16 nM.
    categoryAntineoplastic Agents(c1417)
    cas_num147-94-4

    Basic Info
    Product Name:

    Cytarabine

    Other Name:

    2(1H)-Pyrimidinone,4-amino-1-β-D-arabinofuranosyl-;Cytosine,1-β-D-arabinofuranosyl-;4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone;4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine;1-(Arabinofuranosyl)cytosine;Cytarabine;Aracytidine;ara-Cytosine;1-β-D-Arabinosylcytosine;1-β-Arabinofuranosylcytosine;(Arabinofuranosyl)cytosine;Cytosine β-D-arabinofuranoside;Cytosar;Cytarabinoside;U 19920;Ara-C;NSC 63878;Ac 1075;U 19920A;Cytarabin;Spongocytidine;Alexan;Cyclocide;Cytosine-1-β-arabinofuranoside;Cytosine-1-β-D-arabinofuranoside;1-(β-D-Arabinofuranosyl)cytosine;Cytosine β-D-arabinoside;Aracytin;Cytosine arabinoside;Arafcyt;Arabinocytosine;Arabinoside C;Citozar;Udicil;DepoCyte;Aracytine;Iretin;NSC 287459;Cytosar U;CHX 3311;Arabitin;Erpalfa;Tarabine PFS;Ara-cell;Cylocide;DepoCyt;Cylocide N;4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;MK 8242;SCH 900242

    CAS No.:

    147-94-4

    Molecular Formula:

    C9H13N3O5

    InChIKeys:

    InChIKey=UHDGCWIWMRVCDJ-CCXZUQQUSA-N

    Molecular Weight:

    243.22

    Exact Mass:

    243.22

    EC Number:

    205-705-9

    UNII:

    04079A1RDZ

    DSSTox ID:

    DTXSID3022877

    NCI Thesaurus Code:

    C408

    Color/Form:

    Prisms from 50% ethanol|WHITE TO OFF-WHITE CRYSTALLINE POWDER

    ATC Code:

    L01XY01|L01BC01|L - Antineoplastic and immunomodulating agents

    HScode:

    29349990

    Categories:

    Antineoplastic Agents

    Characteristics
    PSA:

    129

    XLogP3:

    -2.1

    Appearance:

    crystalline

    Density:

    1.9±0.1 g/cm3

    Melting Point:

    212-213 °C

    Boiling Point:

    545.7ºC at 760 mmHg

    Flash Point:

    274.1±32.9 °C

    Refractive Index:

    1.756

    Water Solubility:

    H2O: almost transparency;H2O: 50 mg/mL, clear, colorless

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    8.74X10-12 mm Hg at 25 deg C (est)

    Toxicity:

    Oral-rat LD50: > 5000 mg/kg; Oral-Mouse LD50: 3150 mg/kg

    Flammability characteristics:

    Flammable; burning produces toxic nitrogen oxide fumes

    Specific rotation:

    D24 +153° (c = 0.5 in water)

    Odor:

    ODORLESS

    Henrys Law Constant:

    Henry's Law constant = 1.57X10-19 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa = 4.22

    Collision Cross Section:

    150.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Experimental Properties:

    NON-HYGROSCOPIC @ 40 °C|Hydroxyl radical reaction rate constant = 1.23X10-10 cu cm/molec-sec at 25 °C (est)

    Air and Water Reactions:

    Water soluble.

    Reactive Group:

    Alcohols and Polyols

    Hazard Identification

    Classification of the substance or mixture

    Skin sensitization, Category 1

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H317 May cause an allergic skin reaction

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P321 Specific treatment (see ... on this label).

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

    Location:

    Shirley, New York 11967, USA

    Payment Terms:

    TT against copy of documents,D/P

    Average lead Time:

    15

    Total Annual Revenue:

    $1 million-$2.5 million

    Year of Establishment:

    2004

    Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Cytarabine

    120 G May 2, 2025
    Post an enquiry for this product
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