Cytarabine
1 Inquiries
147-94-4
99%
2026-06-30
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Product Description
-
Seller Information
-
Inquiry History
-
Description
ProductName Cytarabine Cat No CEI-0319 Description Cytarabine CAS No 147-94-4 Molecular Weight 243.22 Purity >99% Storage 2 years at -20centigrade Powder Targets DNA synthesis Molecular Formula C9H13N3O5 Solubility DMSO 1 mg/mL, Water 48 mg/mL, Ethanol In vitro Cytarabine (AraC) is phosphorylated into a triphosphate form (Ara-CTP) involving deoxycytidine kinase (dCK), which competes with dCTP for incorporation into DNA, and then blocks DNA synthesis by inhibiting the function of DNA and RNA polymerases. Cytarabine displays a higher growth inhibitory activity towards wild-type CCRF-CEM cells compared to other acute myelogenous leukemia (AML) cells with IC50 of 16 nM. category Antineoplastic Agents(c1417) cas_num 147-94-4 Basic Info-
Product Name:
Cytarabine
Other Name:2(1H)-Pyrimidinone,4-amino-1-β-D-arabinofuranosyl-;Cytosine,1-β-D-arabinofuranosyl-;4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone;4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine;1-(Arabinofuranosyl)cytosine;Cytarabine;Aracytidine;ara-Cytosine;1-β-D-Arabinosylcytosine;1-β-Arabinofuranosylcytosine;(Arabinofuranosyl)cytosine;Cytosine β-D-arabinofuranoside;Cytosar;Cytarabinoside;U 19920;Ara-C;NSC 63878;Ac 1075;U 19920A;Cytarabin;Spongocytidine;Alexan;Cyclocide;Cytosine-1-β-arabinofuranoside;Cytosine-1-β-D-arabinofuranoside;1-(β-D-Arabinofuranosyl)cytosine;Cytosine β-D-arabinoside;Aracytin;Cytosine arabinoside;Arafcyt;Arabinocytosine;Arabinoside C;Citozar;Udicil;DepoCyte;Aracytine;Iretin;NSC 287459;Cytosar U;CHX 3311;Arabitin;Erpalfa;Tarabine PFS;Ara-cell;Cylocide;DepoCyt;Cylocide N;4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;MK 8242;SCH 900242
CAS No.:147-94-4
Molecular Formula:C9H13N3O5
InChIKeys:InChIKey=UHDGCWIWMRVCDJ-CCXZUQQUSA-N
Molecular Weight:243.22
Exact Mass:243.22
EC Number:205-705-9
UNII:04079A1RDZ
DSSTox ID:DTXSID3022877
NCI Thesaurus Code:C408
Color/Form:Prisms from 50% ethanol|WHITE TO OFF-WHITE CRYSTALLINE POWDER
ATC Code:L01XY01|L01BC01|L - Antineoplastic and immunomodulating agents
HScode:29349990
Categories:
Characteristics-
PSA:
129
XLogP3:-2.1
Appearance:crystalline
Density:1.9±0.1 g/cm3
Melting Point:212-213 °C
Boiling Point:545.7ºC at 760 mmHg
Flash Point:274.1±32.9 °C
Refractive Index:1.756
Water Solubility:H2O: almost transparency;H2O: 50 mg/mL, clear, colorless
Storage Conditions:2-8°C
Vapor Pressure:8.74X10-12 mm Hg at 25 deg C (est)
Toxicity:Oral-rat LD50: > 5000 mg/kg; Oral-Mouse LD50: 3150 mg/kg
Flammability characteristics:Flammable; burning produces toxic nitrogen oxide fumes
Specific rotation:D24 +153° (c = 0.5 in water)
Odor:ODORLESS
Henrys Law Constant:Henry's Law constant = 1.57X10-19 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa = 4.22
Collision Cross Section:150.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:NON-HYGROSCOPIC @ 40 °C|Hydroxyl radical reaction rate constant = 1.23X10-10 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions:Water soluble.
Reactive Group:Alcohols and Polyols
Hazard IdentificationClassification of the substance or mixture
Skin sensitization, Category 1
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H317 May cause an allergic skin reaction
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Location:
Shirley, New York 11967, USA
-
Payment Terms:
TT against copy of documents,D/P
-
Average lead Time:
15
-
Total Annual Revenue:
$1 million-$2.5 million
-
Year of Establishment:
2004
-
-
Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
United States
Cytarabine
120 G May 2, 2025 Post an enquiry for this product