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NU 1025

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CAS No.:

90417-38-2

Content:

95%

Sample Available:

Yes

Price valid (until):

2026-11-14

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Creative Enzymes

Company Type:

Manufactory

Location:

United States

Payment Terms:

TT against copy of documents,D/P

Average Lead Time:

15 days

Qualification:

Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

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Product Description
Seller Information

Description

ProductName	NU 1025
Cat No	CEI-0604
Description	A potent poly(ADP-ribose) polymerase (PARP) inhibitor (IC50 = 400 nM). Useful to study the regulation of deoxyribonucleic acid repair by PARP enzyme.
Alias	NSC 696807
Appearance	White to off-white solid
Product Overview	A potent PARP inhibitor
CAS No	90417-38-2
Molecular Weight	454
Purity	>95%
Storage	-20 centigrade
Synonyms	NSC 696807
Targets	PARP1
Molecular Formula	C9H8N2O2
Chemical Name	8-hydroxy-2-methyl-4(3H)-quinazolinone
Solubility	DMSO
Shipping Conditions	Gel pack
category	Inhibitors(c1514)
cas_num	90417-38-2

ECHEMI Editorial Reference

NU1025 is a potent PARP inhibitor with an IC50 of 400 nM and a Ki of 48 nM. NU1025 potentiates the cytotoxicity of ionizing radiation and anticancer drugs. NU1025 has anti-cancer and neuroprotective activity[1][2][3].

Basic Info

Product Name:

8-Hydroxy-2-methyl-4(3H)-quinazolinone

Other Name:

4(3H)-Quinazolinone,8-hydroxy-2-methyl-;4(1H)-Quinazolinone,8-hydroxy-2-methyl-;8-Hydroxy-2-methyl-4(3H)-quinazolinone;Nu 1025;NSC 696807

CAS No.:

90417-38-2

Molecular Formula:

C9H8N2O2

InChIKeys:

InChIKey=YJDAOHJWLUNFLX-UHFFFAOYSA-N

Molecular Weight:

176.17

Exact Mass:

176.17

HScode:

29335990

Categories:

Inhibitors

Characteristics

PSA:

61.7

XLogP3:

0.35

Appearance:

off-white solid

Density:

1.4±0.1 g/cm3

Melting Point:

248 °C

Boiling Point:

345.4±44.0 °C at 760 mmHg

Flash Point:

162.7±28.4 °C

Refractive Index:

1.678

Water Solubility:

DMSO: 35 mg/mL, soluble

Storage Conditions:

−20°C

See More 8-Hydroxy-2-methyl-4(3H)-quinazolinone Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 8-Hydroxy-2-methyl-4(3H)-quinazolinone Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

Location:
Shirley, New York 11967, USA

Payment Terms:
TT against copy of documents,D/P

Average lead Time:
15 days

Total Annual Revenue:
$1 million-$2.5 million

Year of Establishment:
2004

Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.
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NU 1025

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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