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SR3677

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CAS No.:

1072959-67-1

Content:

95%

Price valid (until):

2026-06-30

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Creative Enzymes

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Manufactory

Location:

United States

Qualification:

Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

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Description

ProductName	SR3677
Cat No	CEI-1112
Description	SR3677 is a potent and selective ROCK-II inhibitor with an IC50 of ~3 nM in enzyme and cell based assays. It displayed an off-target hit rate of 1.4% against 353 other kinases and only inhibited 3 out of a panel of 70 non-kinase enzymes and receptors in profiling studies.
Abbr	SR3677(ROCK2)
Alias	ROCK-II
Product Overview	ROCK-II inhibitor
CAS No	1072959-67-1
Molecular Weight	408.45
Purity	> 95%
Stability	2 years -20 centigrade Powder1 month -4 centigrade in DMSOMore than one month -80 centigrade in DMSO
Storage	4 centigrade
Synonyms	ROCK-II
Targets	ROCK-II
IC50	3 nM
Molecular Formula	C22H24N4O4
Chemical Name	N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide
Solubility	DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
category	Specialty Chemicals(c26)
cas_num	1072959-67-1

Basic Info

Product Name:

N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide

Other Name:

SR3677;N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl-2,3-dihydro-1,4-benzodioxin-2-carboxamidehydrochloride;SR 3677 hydrochloride;N-(2-(2-(diMethylaMino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxaMide;SR 3677 dihydrochloride;N-(2-(2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-ca;N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-benzo[b][1,4]dioxin-2-carboxamide;N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide

CAS No.:

1072959-67-1

Molecular Formula:

C22H24N4O4

InChIKeys:

OQWZIAVXCYIZNN-UHFFFAOYSA-N

Molecular Weight:

408.45

Exact Mass:

408.17975526

DSSTox ID:

DTXSID50648693

Categories:

Characteristics

PSA:

92.20000

XLogP3:

3.44510

Density:

1.298

Boiling Point:

646.9±55.0 °C(Predicted)

PKA:

11.90±0.70

See More N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide Properties 

Seller Information

Business Type:
Manufactory

Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

Location:
Shirley, New York 11967, USA

Payment Terms:
TT against copy of documents,D/P

Average lead Time:
15

Total Annual Revenue:
$1 million-$2.5 million

Year of Establishment:
2004

Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.
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SR3677

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