TAK-715
303162-79-0
95%
2026-08-27
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName TAK-715 Cat No CEI-1114 Description TAK-715 is a potent specific inhibitor of the p38α MAP kinase with an IC50 value of 7.1 nM. It inhibited TNF-α production by 87.6% in mice at 10 mg/kg, po and has potential for treatment of TNF-α mediated inflammatory diseases such as rheumatoid arthriti. Abbr TAK-715(MAPK14, TNF) Alias RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha Product Overview p38α MAP kinase CAS No 303162-79-0 Molecular Weight 399.51 Purity > 95% Stability 2 years -20 centigrade Powder1 month -4 centigrade in DMSOMore than one month -80 centigrade in DMSO Storage 4 centigrade Synonyms RP1-179N16.5, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, P38alpha Targets p38alpha, TNF-alpha IC50 7.1 nM, 48 nM Molecular Formula C24H21N3OS Chemical Name N-(4-(2-ethyl-4-m-tolylthiazol-5-yl)pyridin-2-yl)benzamide Solubility DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL category Heterocyclic Compound(c1111) cas_num 303162-79-0 Basic Info-
Product Name:
Tak-715
Other Name:Tak-715;N-(4-(2-Ethyl-4-(3-methylphenyl)-thiazol-5-yl)pyridin-2-yl)benzamide;BenzaMide, N-[4-[2-ethyl-4-(3-Methylphenyl)-5-thiazolyl]-2-pyridinyl]-;N-(4-(2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)-2-pyridyl)benzamide;N-(4-(2-Ethyl-4-(m-tolyl)thiazol-5-yl)pyridin-2-yl)benzamide
CAS No.:303162-79-0
Molecular Formula:C24H21N3OS
InChIKeys:HEKAIDKUDLCBRU-UHFFFAOYSA-N
Molecular Weight:399.52
Exact Mass:399.140533
UNII:WE92U03C5Z
DSSTox ID:DTXSID20184412
Categories:
Characteristics-
PSA:
83.1
XLogP3:5.6
Appearance:faint yellow to dark yellow
Density:1.2±0.1 g/cm3
Flash Point:253.3±28.7 °C
Refractive Index:1.656
Water Solubility:DMSO: >15mg/mL
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H319 Causes serious eye irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product