Argy Wormwood Leaf 99.0% Pale yellow to brownish-yellow powder J001 Dideu

High Quality GMP DMF Argy Wormwood Leaf Producer

What Is Ai Ye

Ai Ye commonly known as Folium Artemisiae Argyi or Argy Wormwood Leaf is the dried leaf of Artemisia argyi Levl. et Vabt, which is a perennial herb belonging to the family Compositae. It is a common traditional Chinese medicine and acupuncture medication, which first appeared in in the Northern and Southern Dynasties (420-589 CE).

There are approximately 478 species of plants in the Artemisia genus, mainly distributed in temperate, cold-temperate, and subtropical regions of Asia, Europe, and North America. Only a small number of species are found in Africa, South America, and Oceania. Some of the species are commonly used medicinal plants, such as Artemisia argyi Levl. et Vabt, A. Annua, A. scoparia, A. capillaris, Artemisia vulgaris, and so on.

Artemisia argyi Levl. et Vabt commonly known as Silvery wormwood, Chinese mugwort, Seomae mugwort, or Gaiyou is a traditional natural medicine that is extensively used worldwide. They are resistant to cold and drought, prefer warm and humid climates, and are suitable for planting in moist and fertile soil. They often grow in wastelands, roadside riverbanks, and mountain slopes at low to mid altitudes.

They are mainly distributed in China, Russia, Mongolia, North Korea, South Korea, and Japan. Although they are ubiquitous in China, the internationally recognized best-quality A. argyi comes from Qiuchun County and adjacent areas in Hubei Province, China (formerly known as Qizhou in ancient China and the hometown of Li Shizhen) [1]. This type of A. argyi, also known as Qi Ai, is a high-quality moxa material for moxibustion therapy.

In the summer, when the flowers of Ai have not yet bloomed, people pick their leaves, remove impurities, dry them in the sun, use them directly, or carbonize them, and make traditional Chinese medicines.

Ai Ye contains 1,8-cineole, caryophyllene, camphor, neointermedeol, caryophyllene oxide, borneol, camphene, D-carvone, bornyl acetate, β-pinene, L-4-terpineol, perilla aldehyde, pinocarvone, sabinene, hexahydrofarnesyl acetone, ascaridole, tricyclene, thujone, humulene, α-pinene, eugenol, terpinene, germacrene, terpinolene, cymene, cinene, 3-carene, 1,3-cyclohexadiene, crithmene, piperitone, isoborneol, carvacrol, thujanol, curcumene, 3-thujene, cedrene, myreene, nepetin, eupatilin, jaceosidin, apigenin, kaempferol, quercetin, luteolin, centaureidin, casticine, hispidulin, rhamnetin, diosmetin, capillarisin, naringenin, isoquercetin, eriodictyolchalcone, acacetin, isorhamnetin, eupatolitin, apicin, moxartenolide, isotanciloide, argyinolide A~I, arteminolide A~D, artanomaloide, artemisian A~D, artemisiane A~D, triterpenes, phenylpropanoids, organic acids, steroids, polysaccharides, and trace elements.

Generally, the soft Ai Ye with grayish-white color on the back, lots of fuzz, and a strong aroma are preferred.

According to the Chinese Pharmacopoeia, the medicinal property of Ai Ye is relatively warm, with slight toxicity, and a bitter and pungent taste. It has a therapeutic effect on pathological changes in the liver, spleen, and kidney meridians.

In Traditional Chinese Medicine, it is often used to warm channels for arrest bleeding, eliminate cold to kill pain, regulate menstrual function, miscarriage prevention, remove dampness to stop itching, and treat hematemesis, nasal Bleeding, uterine bleeding, menorrhagia, vaginal bleeding during pregnancy, cold pain in the lateral lower abdomen, abnormal menstruation, sterility due to uterine cold, vaginitis, erosion of the cervix, eczema, pruritus vulvae, scabies, bronchial asthma, chronic bronchitis, chronic hepatitis, liver cirrhosis, shrinkage of external sex organs, infantile virus enteritis, trigeminal neuralgia, and tertian malaria.

There are over 300 traditional Chinese medicine prescriptions that contain it, such as Ai Fu Nuan Gong Wan, Ai Ye You Jiao Nang, and Shen Rong Bao Tai Wan.

Benefits

Anti-inflammation, inhibited 1-fluoro-2,4-dinitrobenzene-induced ear swelling in CD mice and expression of COX-2 and iNOS and production of NO and PGE2 in LPS-stimulated Raw 264.7 cells [2].

Increasing the tail-flick threshold in rats, prolonging the latency of hot plate response and twisting behavior in mice, and inhibiting the number of twisting behaviors in mice [3].

Anti-oxidation, scavenging ABTS radicals and DPPH radicals, reducing ferric ion (Fe3+) to the ferrous ion (Fe2+) [4].

Prolonging the onset of wheezing in guinea pigs and inhibiting histamine- and acetylcholine-induced asthma in guinea pigs.

Warming channel for arresting bleeding, treating hematemesis, nasal Bleeding, uterine bleeding, and menorrhagia caused by deficiency-cold.

Warming the uterus for dispelling cold, regulating the menstrual function, and treating abnormal menstruation, dysmenorrhea, sterility due to uterine cold, and thin leukorrhea caused by lower burner vacuity cold, or retention of cold in the uterus.

Treating cold pain in the stomach and abdomen caused by deficiency-cold in the spleen and stomach.

Its essential oil significantly inhibits mushroom tyrosinase activity, down-regulates B16F10 intracellular tyrosinase activity, and decreases the amount of melanin content in a dose-dependent pattern [4].

Its tannin compounds have a strong hemostatic effect [5]. In vitro anticoagulation experiments have demonstrated that its flavonoid compound eupatilin 7-O-β-d-pyranosyl glucoside significantly extended thrombin time, and 5,6,2′,4′-tetrahydroxy-7,5′-dimethoxyflavone had an obvious effect in increasing prothrombin time [6].

Its polysaccharides can prevent liver damage caused by acetaminophen. The mechanism of action may be related to the increase in blood glucose concentration and the increase in liver cell energy caused by the elevation of its polysaccharides, as well as the provision of more reduced coenzyme II and reduced glutathione.

Its polysaccharides inhibited the growth of S180 transplanted tumors and prolonged the survival time of tumor-bearing mice [7]. Its extract had marked cytostatic and cytotoxic effects on SMMC-7721 cells and inhibited the SMMC-7721 colony formation in a dose-dependent manner [8].

Its ethyl acetate extract suppressed the in vitro proliferation of human primary T lymphocytes in a concentration-dependent, non-cytotoxic manner. It has immunosuppressive activity [9].

Studies have found that its crude extract has antiviral effects against herpesvirus and rotavirus [10].

Its volatile oil has a good inhibitory effect on Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella, Streptococcus pneumoniae, Corynebacterium diphtheriae, Bacillus anthracis, Pseudomonas aeruginosa, Mycobacterium tuberculosis, and Candida albicans [5].

The decoction of it can be applied topically to remove dampness to stop itching, and treat skin pruritus such as eczema, genital itching, scabies, etc.”

Additionally, by crushing the product and making it into moxa sticks, moxa cones, or other moxa preparations for moxibustion on acupoints of the body’s surface, it can warm and invigorate Qi and blood, penetrate the meridians, and treat illnesses such as cold pain in the lateral lower abdomen, irregular menstruation, and other related symptoms.

Combinations

It can be used in combination with E Jiao (Colla Corii Asini), Bai Shao (White Peony Root), Sheng Di Huang (Radix Rehmanniae), etc., to treat uterine bleeding caused by deficiency-cold of kidney, and debility of Chong and Ren Channels.

It can be used in combination with Sheng Di Huang (Radix Rehmanniae), He Ye (Folium Nelumbinis), Ce Bai Ye (Cacumen Platycladi), etc. to treat hematemesis and nasal Bleeding caused by blood-heat.

It can be used in combination with Xiang Fu (Rhizoma Cyperi), Wu Zhu Yu (Evodiae Fructus), Dang Gui (Radix Angelicae Sinensis), etc., to treat irregular menstruation, dysmenorrhea, sterility due to uterine cold, and thin leukorrhea caused by lower burner vacuity cold.

It can be used in combination with E Jiao (Colla Corii Asini), Sang Ji Sheng (Herba Taxilli), etc., to treat fetal irritability and vaginal bleeding during pregnancy.

It can be used in combination with Dang Gui (Radix Angelicae Sinensis), Gan Jiang (Dried Ginger), Mu Xiang (Radix Aucklandiae), Hou Po (Magnolia Bark), Rou Dou Kou (Semen Myristicae), Cao Guo (Fructus Tsaoko), Gao Liang Jiang (Rhizoma Alpiniae Officinarum), Ding Xiang (Flos Caryophylli), and Gan Cao (Licorice Root) to treat abdominal pain and cold dysentery in children.

Our normal packaging is 25kgs/Drum

The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.

a) Free sample can be supplied.

b) Guide our clients by professional knowledge and teach them how to use our product after sales.

c) Accept SGS, BV any other third-party inspection before loading.

d) High quality best price Guaranteed.

Why do you choose Dideu as your partner?

A) High quality can be guaranteed. Dideu since 1975 are reputed chemical manufacturer and are Certified by ISO 9001;2015 and have GMP certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P, D/A payment term. If there is any quality problem after goods arrive. Dideu will do fully payment refund.

B) Best price can be guaranteed. As Dideu are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.

C) Professional engineers from Dideu will give professional usage guide and services after sales.

D)Dideu work 7×24 hours and your request will be processed by our professional staff in different shift period.

Dideu is one of the largest producer for general chemical, pharmaceutical, nutrition additive, natural extracts, agrochemical and Daily-Use Chemical in China and is headquartered in Shaanxi, China. The Dideu Group comprises subsidiaries and joint ventures in more than 10 countries and operates six integrated production sites and 21 other production sites in Europe, Asia, Australia, Americas and Africa. Its headquarters is located in Xi’An,China. Dideu has customers in over 200 countries and supplies products to a wide variety of industries.

At the end of 2014, the company employed more than 13000 people. In 2014, Dideu Group posted sales of 30 billion and income from operations before special items of about 7.5 billion. The company is currently expanding its international activities with a particular focus on Asia countries. Between 1990 and 2005, the company invested 5.2 billion in Asia, for example in sites near Guangxi,Yunnan, Sichuan, Shaanxi China, Mangalore in India,Bangkok, Thailand,Hanoi, Vietnam etc.

Dideu Consist Of Five Industry Chains:

1. 1）Pharmaceutical Industries
2. 2）Nutrition Additive Industries
3. 3）Daily-Use Chemical Products Industries & Agrochemicals
4. 4）Environmental Friendly Chemical And Chemurgy Industries
5. 5）Petrochemical Industries
6. 6）General Chemical Industry

At Dideu, we redefine chemistry to make the world better - and have been doing so for 75 years. As one of the world's leading chemical company, we combine economic success with environmental protection and social responsibility. Through science and innovation we enable our customers in nearly every industry to meet the current and future needs of society.

At Dideu, we create chemistry for a sustainable future with science for a better life. Dideu is a Life Science company with a long and glorious history and core competencies in the areas of health care and agriculture. With our innovative products, we are contributing to finding solutions to some of the major challenges of our time. The growing and increasingly aging world population requires improved medical care and an adequate supply of food. Dideu is improving people's quality of life by preventing, alleviating and treating diseases. And we are helping to provide a reliable supply of high quality food, feed and plant based raw materials. We develop new molecules for use in innovative products and solutions to improve health. Our research and development activities are based on a profound understanding of the biochemical processes in living organisms. Our goal is to achieve and sustain leadership positions in our markets, thus creating value for our customers, stockholders and employees. To this end, our strategy is designed to help solve some of the most pressing challenges facing humankind, and by doing this exceptionally well we aim to strengthen the company's earning power.

We are committed to operating sustainably and addressing our social and ethical responsibilities as a corporate citizen, while at the same time respecting the interests of all our stakeholders. Employees with a passion for innovation enjoy excellent development opportunities at Dideu. Exclusive Focus on the Life Science Businesses Following the economic and legal independence of our former Material Science subgroup. Dideu has charted the course for its successful development as a Life Science company. Our Life Science businesses hold leading positions in innovation driven growth markets. Together they make up a strong, attractive and balanced portfolio that is resistant to fluctuations in demand and to potential risks.The previous structure comprising a strategic management holding company and operational subgroups has thus been replaced by an integrated organization under the umbrella of the strong Dideu brand. The company's operations are managed in three divisions Pharmaceuticals, Consumer Health and Crop Science and the Animal Health business unit. The business continues to be supported by the corporate functions, Dideu Business Services and the service company Current, while Technology Services is being integrated into Dideu Group, forming the Engineering and Technology function.