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L-Valine 72-18-4

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CAS No.:

72-18-4

Packaging:

bag/drum

Price valid (until):

2023-05-24

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SHANDONG LOOK CHEMICAL CO.,LTD

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Amino acids	L-Valine is a kind of branched-chain amino acids (BCAA). Animal cannot synthesize it by itself. It must be obtained from the diet to meet their nutritional needs. Therefore L-valine belongs to the essential amino acids. Amino acids are the basic structural unit of protein synthesis, and the predecessor of other amines that metabolism needs. They are indispensable materials in our life. At present, it is known that there are 20 to 30 amino acids. Some of them can be synthesized in the human body, which are known as non-essential amino acids. And some, called essential amino acids, cannot be synthesized in the human body that should be supplemented from the outside. Mammal cells need twelve essential amino acids: L-arginine, L-cystine, L-histidine, L-leucine, L-isoleucine, L-lysine, L-methionine, L-phenylalanine, L-threonine, L-tryptophan, L-tyrosine, L-valine. These amino acids are all laevoisomer, and some non-essential amino acids of dextroisomer may have inhibitory effect on cultured cells. L-amino acids can easier to be absorbed than D-amino acids. And the absorption of D, L-methionine has no difference. There is competition between the body transport of amino acids. The transporting of an amino acid can be suppressed by the presence of another amino acid. For example, L-valine and L-methionine can inhibit the absorption of L-leucine. Excessive lysine in dietary can inhibit the absorption of arginine. High concentration (100mM) of L-valine has no effect on the absorption of L-methionine. Because it can be transported through another route.
Content Analysis	About 200mg sample is accurately weighed, dissolved in 3ml formic acid and 50ml glacial acetic acid. Add 2 drops of crystal violet test solution (TS-74), then use 0.1mol/L perchloric acid to titrate the solution to green or blue disappear entirely. Each Ml0.1mol/L perchloric acid is equivalent to 11.72mg L-valine (C5H11NO2).
Chemical property	White crystal or crystalline powder, odorless, bitter taste. Soluble in water, solubility in water of 8.85% at 25℃. Almost insoluble in ethanol, ether, acetone. melting point(decomposition point) 315℃, isoelectric point 5.96, [α]25D+28.3 (C = 1-2g/ml, in 5mol/L HCl).
Uses	Amino acids drugs, nutritional supplements. It can be used as the main component of aminophenol transfusion and synthesize aminophenol. L-Valine is one of the three branched-chain amino acids. It is essential amino acid. It can be used to treat liver failure and central nervous system dysfunction. L-Valine is essential amino acid. The requirement for men is 10mg/(kg·d). Physiological effects of the L-form is 2 times of the D-type. L-Valine deficiency can cause neurological disorders, blastocolysis, loss of weight, anemia and the like. As nutritional supplements, it can be used to prepare aminophenol transfusion and synthesize aminophenol with other essential amino acid infusion. Valine added to metric pastry (1g/kg) can make the products aroma of sesame. L-Valine used in bread can also improve the flavor. L-Valine is the essential amino acid. It can be used as one of pharmaceutical composition of amino acid infusion to synthesize drugs. It also can be used as food additives. Nutritional supplements. It can be used to prepare aminophenol transfusion and synthesize aminophenol with other essential amino acid infusion.Valine added to metric pastry (1g/kg) can make the products aroma of sesame. L-Valine used in bread can also improve the flavor. L-Valine can be used for biochemical research, the preparation of tissue culture media. It also used as amino acids nutritional drugs in medicine.

Basic Info

Product Name:

L-Valine

Other Name:

L-Valine;Valine,L-;L-(+)-α-Aminoisovaleric acid;Valine;Butanoic acid,2-amino-3-methyl-,(S)-;(S)-2-Amino-3-methylbutyric acid;2-Amino-3-methylbutanoic acid;(S)-Valine;(S)-2-Amino-3-methylbutanoic acid;(S)-α-Amino-β-methylbutyric acid;L-α-Amino-β-methylbutyric acid;NSC 76038;(2S)-2-Amino-3-methylbutanoic acid;(+)-2-Amino-3-methylbutyric acid;(2S)-2-Amino-3-methylbutanoic acid;(2S)-2-Azaniumyl-3-methylbutanoate;7004-03-7;16872-32-5;154605-70-6;1613375-16-8

CAS No.:

72-18-4

Molecular Formula:

C5H11NO2

InChIKeys:

InChIKey=KZSNJWFQEVHDMF-BYPYZUCNSA-N

Molecular Weight:

117.15

Exact Mass:

117.15

BRN:

1721136

EC Number:

200-773-6

UNII:

HG18B9YRS7

NSC Number:

760111

NCI Thesaurus Code:

C29604

Color/Form:

Leaflets from water + alcohol|White, crystalline solid

HScode:

29224995

Categories:

Amino Acids and Proteins

Characteristics

PSA:

63.3

XLogP3:

-2.3

Appearance:

White powder

Density:

1.32 g/cm³

Melting Point:

315 °C

Boiling Point:

Sublimes

Flash Point:

83.0±22.6 °C

Refractive Index:

1.461

Water Solubility:

H2O: 85 g/L (20 ºC)

Storage Conditions:

Store at RT.

Vapor Pressure:

5.55X10-9 mm Hg at 25 deg C (est)

Toxicity:

LD50 intraperitoneal in rat: 5390mg/kg

Specific rotation:

28 º (c=8, 6N HCl)

PKA:

2.3(at 13 °C)

Henrys Law Constant:

Henry's Law constant = 2.63X10-9 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

2.3 (at 13 °C)|pKa = 2.30

Collision Cross Section:

134.28 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|144.07 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|132.88 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|120.9 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|133.4 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|124.3 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|124.9 Å² [M-H]-

Experimental Properties:

Sublimes without melting at ordinary speed of heating. Decomposes at 298 °C (closed capillary, very rapid heating). One part dissolves in 11.7 parts of water at 15 °C, in 14.1 parts of water at 25 °C. Insoluble in common neutral solvents. /Valine DL-form/|UV: 3-46 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /Valine (DL)/|Raman: 426 (Sadtler Research Laboratories spectral collection) /Valine (DL)/

See More L-Valine Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More L-Valine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

Location:
hisense intelligence valley,no 2116,of phoenix road

Payment Terms:
TT against copy of documents,D/P,L/C

Average lead Time:
7

Total Annual Revenue:
Less than $1 million

Total Employees:
11-50

Year of Establishment:
2017

SHANDONG LOOK CHEMICAL CO.LTD, a new chemical enterprise in researching, manufacturing and supplying of chemicals located in beautiful “Spring City”-Jinan.Our company mainly working on the researching new-born APIs, intermediate ( especially Carbohydrate derivatives series). Meanwhile, we made huge breakthrough in industries of food, feed additives, cosmetics ,dye and industrial chemicals. Our company enjoyed great reputation both domestic and abroad under the belief of “Integrity management,Quality controlling and Customer orientation”. Web : www.chinalookchemical.com

We had been cooperated with NingXia University and Shandong University on more than ten projects for years and which had been in mass production on the market. We now have more than 80 people in our team and built research center in Jinan and Ningxia. Our manufacturing site allocated in chemical industry parks of Zhangqiu, Heze, Dezhou and Ningxia Fine Chemical Park. We strictly complying with ISO9001 and ISO 2000 standard in manufacturing process, our lab and workshop tightly in accordance with GMP standard.Our products best selling in Europe, South and North America,Asia pacific area and Africa. We sincerely welcome new and regular customers around the world visit us for business negotiation.

Inquiry History

32 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	L-Valine	10.00 TON	Mar 15, 2024
India	L-Valine	10 TON	Mar 14, 2024
India	L-Valine	10 MT	Jul 15, 2025
India	L-Valine	1 MT	Apr 23, 2025
India	L-Valine	25 KG	Apr 21, 2025
United Kingdom	Valine	1.00 20' Fcl	Apr 2, 2025
Czech	Valine	12000 KG	Dec 16, 2024
United Kingdom	Valine	30.00 MT	Nov 22, 2024
United States	L- Valine	10 MT	Oct 18, 2024
Russia	L-Valine	25 KG	Sep 24, 2024
Egypt	L-Valine	500 KG	Jun 28, 2024
Spain	L-Valine	25 MT	Sep 26, 2023
Turkey	L-VALINE	1 MT	Feb 4, 2026
Greece	VALINE (Val,V)	1000.00 KG	Sep 24, 2025
India	L-valine	1 20' Fcl	Feb 7, 2025
Brazil	valine	27 TON	Oct 31, 2024
Egypt	L-Valine	500 KG	Apr 19, 2024
Russia	L-Valine	50 KG	Jul 16, 2026
Mexico	L-Valine	25 KG	Jan 13, 2026
Indonesia	valin	1.00 20' Fcl	Oct 20, 2023

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L-Valine 72-18-4

Product Description

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