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4-[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile

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CAS No.:

577778-58-6

Grade:

Industrial Grade

Content:

99%

Port:

beijing

Brand:

SHANDONG BOYUAN

Packaging:

25kg

Price valid (until):

2024-08-31

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Shandong Boyuan Pharmaceutical Co., Ltd.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Terbinafine hydrochloride,Carboplatin,Pramipexole dihydrochloride Monohydrate,Cisatracurium Besylate,Rivaroxaban,Lenvatinib

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Product Description
Seller Information
Inquiry History

Description

FYX051;Topiroxostat;Topiroxostat,FYX-051;5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole;Topiroxostat5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazolChemicalbooke;4-[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile;2-Pyridinecarbonitrile,4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-;Topiroxostatimpurty

Introduction Topiroxostat (FYX-051), chemical name 5-(2-cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole, is made of A non-purine selective xanthine oxidoreductase inhibitor that selectively and reversibly inhibits xanthine oxidoreductase and reduces serum uric acid value researched and developed by Fuji Pharmaceutical Co., Ltd. of Japan. Action: Topirastat competitively inhibits purine oxidoreductase, thereby inhibiting the production of uric acid. It has no blocking effect on other pyrimidine-purine metabolism enzymes, but shows selective blocking effect on xanthine oxidoreductase. Topinostat has a significant inhibitory effect on both oxidized and reduced XOR, so its uric acid-lowering effect is more powerful and lasting. Therefore, this product can be used to treat chronic hyperuricemia in gout. Indications apply to gout and hyperuricemia.

Topiroxostat (FYX-051), chemical name 5-(2-cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazoleChemicalbook, is produced by A non-purine selective xanthine oxidoreductase inhibitor that selectively and reversibly inhibits xanthine oxidoreductase and reduces serum uric acid value researched and developed by Fuji Pharmaceutical Co., Ltd. of Japan.

Items	Specifications
solubility	DMSO : 23.5 mg/mL (94.67 mM; Need ultrasonic and warming)
InChI	InChI=1S/C13H8N6/c14-8-11-7-10(3-6-16-11)13-17-12(18-19-13)9-1-4-15-5-2-9/h1-7H,(H,17,18,19)
STORAGE	Store at -20°C

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Basic Info

Product Name:

Topiroxostat

Other Name:

2-Pyridinecarbonitrile,4-[3-(4-pyridinyl)-1H-1,2,4-triazol-5-yl]-;2-Pyridinecarbonitrile,4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-;4-[3-(4-Pyridinyl)-1H-1,2,4-triazol-5-yl]-2-pyridinecarbonitrile;5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole;FYX 051;Topiroxostat

CAS No.:

577778-58-6

Molecular Formula:

C13H8N6

InChIKeys:

InChIKey=UBVZQGOVTLIHLH-UHFFFAOYSA-N

Molecular Weight:

248.249

Exact Mass:

248.24

UNII:

0J877412JV

DSSTox ID:

DTXSID80206462

Categories:

Antineoplastic Agents

Characteristics

PSA:

91.1

XLogP3:

1.2

Density:

1.5±0.1 g/cm3

Boiling Point:

594.7±60.0°C at 760 mmHg

Flash Point:

175.3±18.1 °C

Refractive Index:

1.697

See More Topiroxostat Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Topiroxostat Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Terbinafine hydrochloride,Carboplatin,Pramipexole dihydrochloride Monohydrate,Cisatracurium Besylate,Rivaroxaban,Lenvatinib

Location:
NO.28 SangYuan Rd,JinanCity,ShanDong Province,China

Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
1

Total Annual Revenue:
$50 million-$100 million

Total Employees:
501-1000

Year of Establishment:
2005

Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Topiroxostat	10 G	Jan 21, 2024
India	Topiroxostat	5	Mar 12, 2024
India	Topiroxostat	1 G	Dec 15, 2023
India	topiroxostat	10 G	Sep 26, 2023

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