TITANIUM DIXOIDE

This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006 as amended by Regulation (EC) No 1272/2008 and Commission Regulation (EU) No

453/2010.

Issuing date：01-01-2010              Revision Date：01-01-2019                   Ref：20190101

Other Hazards

Inhalation: Inert nuisance dust. Temporary drying effect and/or irritation of mucous membranes may result from excessive exposure. Exposure to dust may aggravate  pre-existing respiratory conditions.

Skin: Non-corrosive and non-sensitising. Prolonged contact may result in rashes /

irritations due to drying of the skin and/or mechanical abrasion related to skin-to-clothing contact or skinto-skin contact. Skin absorption is not applicable.

Eyes: Avoid contact with eyes.

Ingestion: No adverse health effects anticipated by this route during proper industrial handling.

SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS

SECTION 4：FIRST AID MEASURES

Description of necessary first-aid measures

Eye Contact: In the case of contact with eyes, rinse immediately with plenty of water. If symptoms persist, call a physician.

Skin contact: Wash skin with soap and water. Use of moisturizer maybe helpful.

Ingestion: No adverse health effects anticipated by this route during proper industrial

handling. In the event of ingestion, increase intake of liquid in order to flush from body. If symptoms persist, call a physician.

Inhalation:   Move to fresh air.

Most important symptoms and effects, both acute and delayed

Most Important Symptoms/Effects Nuisance dust.

Indication of immediate medical attention and special treatment needed

Notes to Physician None.

SECTION 5. FIRE-FIGHTING MEASURES

Extinguishing media - large fires

Suitable Extinguishing Media

Not flammable. Use extinguishing agent suitable for surrounding fire.

Extinguishing media which must not be used for safety reasons

None.

Special hazards arising from the substance or mixture

None.

Special Protective Equipment for Firefighters

As in any fire, wear self-contained breathing apparatus and full protective gear.

SECTION 6. ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Avoid inhalation of dust by arranging adequate ventilation, or use an appropriate dust mask. Avoid excessive contact with the skin.

Other Information

Refer to Section 13 for disposal considerations.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Use dyking or absorbant to prevent run-off from entering waterways.

Methods and materials for containment and cleaning up

Methods for Cleaning up

Use any feasible mechanical means (e.g. vacuuming, absorbent material).

SECTION 7. HANDLING AND STORAGE

Precautions for Safe Handling

Handling

Take precautionary measures against static discharges. Minimize inhalation of dust and contact with the skin.

Conditions for safe storage, including any incompatibilities

To guarantee the quality and properties of the product keep protected from humidity and bad weather conditions. Avoid prolonged

storage. Product maybe packaged in normal commercial packaging; paper or plastic material. Caution: The stacking height must

not exceed 3 pallets. Do not store flexible containers on top of each other. Refer to the

detailed list of incompatible materials

(section 10 "Stability/Reactivity").

Specific End Uses

Specific Uses Take precautions against the discharge of static electricity during powder

handling

operations.

Exposure Scenario None required as mixture is not hazardous.

Other Guidelines None.

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Components with workplace control parameters

Derived No Effect Level (DNEL): 10 mg/m3

Predicted No Effect Concentration (PNEC):    Marine water: >1 mg/l; sediment: >100 mg/kg Freshwater: = 0.127 mg/l; sediment: >1000 mg/kg

Exposure controls

Engineering Measures: Good natural ventilation will be sufficient in most circumstances. Local exhaust ventilation maybe necessary if airborne dust concentration approaches

the exposure limit (s).

Personal protective equipment

Eye Protection: Safety glasses with side-shields or goggles.

Hand Protection: Impervious gloves.

Skin and Body Protection: Long sleeved clothing.

Respiratory Protection: In the event of insufficient ventilation: Respiratory protective device with a particles filter.

Environmental Exposure Controls:   Do not allow material to contaminate ground water system.

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES

Physical State:   Solid

Appearance:    White

Odor:   None

pH : Not applicable

Vapor Pressure:   Not applicable

Vapor Density:   Not applicable

Viscosity : Not applicable

Boiling Point/Range:   Not applicable

Melting Point/Range:    1830°C

Decomposition Temperature:   No data available

Explosive Properties:   Not applicable

Flash Point : Not applicable

Oxidizing Properties:   Not applicable

Evaporation Rate:   Not applicable

Flammability (solid, gas):   Not applicable

Water Solubility:   Insoluble in water

Solubility in other solvents:   Insoluble in ether

Specific Gravity:   4.0 - 4.2

VOC Content(%):   None

SECTION 10. STABILITY AND REACTIVITY

Reactivity

None.

Chemical Stability

Stable under normal conditions.

Possibility of Hazardous Reactions

None under normal processing.

Conditions to Avoid

None.

Materials to Avoid

None.

Hazardous Decomposition Products

None.

SECTION 11. TOXICOLOGICAL INFORMATION

Acute toxicity

Product Information：These products do not present an acute toxicity hazard based on known or supplied information.

Irritation： Same as a nuisance dust.

Ingestion  ：No known toxic effect.

Skin Contact： No known effect.

Inhalation  ：No known toxic effect.

Eye Contact： No known toxic effect.

Corrosivity： Individuals with sensitive skin may experience skin drying on prolonged or repeated exposure.

Component Information

Chronic Effects

Carcinogenicity：Titanium Dioxide is listed by IARC as possibly carcinogenic to humans (Group 2B). This listing is based on inadequate evidence of carcinogenicityin humans

and sufficient evidence in experimental animals.

Sensitization: No evidence of skin or respiratory sensitisation.

Mutagenic Effects:   None known.

Reproductive Toxicity:   None known.

Developmental Toxicity； None known.

STOT - single exposure  ：Not classified.

STOT - repeated exposure： Not classified.

Target Organ Effects： In lifetime inhalation studies of rats, airborne respirable-size

titanium dioxide particles have been shown to cause lung tumors at concentrations

associated with substantial particle lung burdens and consequential pulmonary overload and inflammation. However, other laboratory animals such as mice and hamsters did not develop lung tumors under similar testing with titanium dioxide. Furthermore, human

epidemiology studies do not suggest an association between occupational exposure to titanium dioxide and risk for cancer.

Aspiration Hazard： None known.

Endocrine Disruptor Information： These products do not contain any known or

suspected endocrine disruptors.

SECTION 12. ECOLOGICAL INFORMATION

Toxicity

Ecotoxicity effects

None known.

Persistence and degradability

Titanium dioxide is persistent and does not biodegrade.

Bioaccumulative potential

Does not bioaccumulate.

Mobility in soil

There is no evidence of mobility of these products (solid particles).

PBT and vPvB assessment

Not PBT and not vPvB.

SECTION 13. DISPOSAL CONSIDERATIONS

Waste treatment

Waste from Residues / Unused Products：

These products are not considered hazardous for disposal into sanitary landfill or

industrial waste disposal landfill. Please review appropriate national and local waste regulations.

Contaminated Packaging：

Contaminated packages are not considered hazardous for disposal into sanitary landfill

or industrial waste disposal landfill. Please review appropriate national and local waste

regulations.

EWC Waste Disposal No EWC Code: 06 11 99. Not classified as a hazardous waste.

SECTION 14. TRANSPORT INFORMATION

IMDG/IMO： Not regulated

RID：Not regulated

ADR：Not regulated

ICAO： Not regulated

IATA： Not regulated

SECTION 15. REGULATORY INFORMATION

These products are not classified as dangerous according to Directives 67/548/EEC and 1999/45/EC.

Labeling

Symbol(s) Not dangerous.

International Inventories

The products on this MSDS comply with the country chemical control inventories listed below.

USA (TSCA) Complies

European Union (EINECS) Complies

Canada (DSL/NDSL) Complies

Philippines (PICCS) Complies

Japan (ENCS) Complies

China (IECSC) Complies

Australia (AICS) Complies

Korea (KECL) Complies

New Zealand (NZIoC) Complies

Legend

TSCA - United States Toxic Substances Control Act Section 8(b) Inventory

EINECS/ELINCS - European Inventory of Existing Commercial Chemical Substances/EU List of Notified Chemical Substances

DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List

PICCS - Philippines Inventory of Chemicals and Chemical Substances

ENCS - Japan Existing and New Chemical Substance