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API Raw Material 5 Aminoleuvlinic Acid HCL 99%

Name: API Raw Material 5 Aminoleuvlinic Acid HCL 99%
Brand: HANDOM CHEM
SKU: pr2402211281
Price: 680 USD
Availability: InStock

3 Inquiries

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CAS No.:

5451-09-2

Grade:

Pharmaceutical Grade

Content:

98%

Port:

Shanghai or Beijing

Brand:

HANDOM CHEM

Packaging:

1kg/Aluminum Foil Bag

Price valid (until):

2024-03-21

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DALIAN HANDOM CHEMICALS CO.,LTD.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

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Product Description
Seller Information
Inquiry History

Description

Product Details

5-Aminolevulinic acid HCl, the CAS number is: 5451-09-2, which is an intermediate in heme biosynthesis in the body and a prodrug of tetrapyrrole.

Test Items	Specifications
Appearance	White or almost white powder
Identification	1. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay. 2. Consistent with the IR spectrum of the Standard. 3. Meets the requirements of Chloride.
pH Value	2.5 ~ 2.9
Loss on Drying	Not more than 0.5%
Residue on Ignition	Not more than 0.3%
Assay	Aminolevulinic Acid Hydrochloride contains NLT 98.0% and NMT 102.0% (Calculated on the anhydrous basis)
Related Substances	Aminolevulinic acid related compound A: ≤0.15%
	Aminolevulinic acid related compound B: ≤0.15%
	Any individual unspecified impurity: ≤0.10%
	Any other total impurities: ≤0.5%
Residual Solvents	Acetic Acid≤5000ppm
	Acetone≤5000ppm
	N-heptane≤5000ppm
	Ethyl acetate≤5000ppm
	Tetrahydrofuran≤720ppm

Executive Standards:

USP40 & In-house.

Packaging:

1kg/Aluminum Foil Bag, 5kg/Carton, 10kg/Carton.

ECHEMI Editorial Reference

5-Aminolevulinic acid HCl is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.Target: Others5-Aminolevulinic acid is a non-fluorescent prodrug that leads to intracellular accumulation of fluorescent porphyrins in malignant gliomas-a finding that is under investigation for intraoperative identification and resection of these tumours. Median follow-up was 35.4 months (95% CI 1.0-56.7). Contrast-enhancing tumour was resected completely in 90 (65%
5-aminolevulinic acid hydrochloride is a hydrochloride that is the monohydrochloride of 5-aminolevulinic acid. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. It has a role as an antineoplastic agent, a photosensitizing agent, a dermatologic drug and a prodrug. It contains a 5-ammoniolevulinic acid.|Aminolevulinic Acid Hydrochloride is the hydrochloride salt form of aminolevulinic acid, an aminoketone, used for local photosensitizing therapy. Aminolevulinic acid (ALA) is a metabolic pro-drug that is converted into the photosensitizer protoporphyrin IX (PpIX), which accumulates intracellularly. Upon exposure to light of appropriate wavelength (red, or blue), PpIX catalyzes oxygen to singlet oxygen, an intracellular toxin, which can further react to form superoxide and hydroxyl radicals. This leads to cellular cytotoxic effects.|A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
white to pale yellow crystals or
Dry ALA-HCl in a vacuum desiccator over P2O5 overnight, then crystallise it by dissolving it in cold EtOH and adding dry Et2O. Also crystallis

Basic Info

Product Name:

5-Aminolevulinic acid hydrochloride

Other Name:

5-AminoL;evuL;inic acid hydrochL;TIMTEC-BB SBB003880;DELTA-AMINOLEVULINIC ACID HYDROCHLORIDE CELL CULTUR;5-AminolevulinicAcidHydrochloride(5-Ala);5-Ala;5-Aminolevulinicacidhydrochloride,99%

CAS No.:

5451-09-2

Molecular Formula:

C5H10ClNO3

InChIKeys:

ZLHFONARZHCSET-UHFFFAOYSA-N

Molecular Weight:

167.59

Exact Mass:

167.035

BRN:

3690651

EC Number:

226-679-5

UNII:

V35KBM8JGR

NSC Number:

758687|18509

DSSTox ID:

DTXSID5045914

NCI Thesaurus Code:

C1849

Color/Form:

White to pale yellow

ATC Code:

L01XD04

HScode:

29224999

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

80.39000

XLogP3:

-0.79

Appearance:

White to pale yellow powder

Density:

1.2±0.1 g/cm3

Melting Point:

~150 °C (dec.)

Boiling Point:

311.5±27.0 °C at 760 mmHg

Flash Point:

155-157°C

Refractive Index:

1.482

Water Solubility:

Soluble in dimethyl sulfoxide, methanol and water.

Storage Conditions:

2-8°C

PH:

pH (10g/l, 25℃) : 2.5～3.0

Critical Temperature & Pressure:

-20°C

See More 5-Aminolevulinic acid hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 5-Aminolevulinic acid hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2020

Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	API Raw Material 5 Aminoleuvlinic Acid HCL 99% white powder cas 5451-09-2 EGC 5-Aminolevunlinic Acid	1 MT	Feb 16, 2024
Taiwan, China	5-Aminolevulinic Acid Hydrochloride	1 KG	Jan 9, 2024
Spain	5-aminolevulinic acid	100 KG	Sep 3, 2024

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