DL-Methyldopa Methyldopa CAS NO: 41372-08-1
GMP
41372-08-1
Pharmaceutical Grade
99%
SHANGHAI
25kg drum
2024-05-08
EXCIPIENTS,POVIDONE,AMINO ACIDS,API,VITAMINS
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceL-(-)-α-Methyldopa hydrate is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.Target: alpha-adrenergic agonistMethyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents. However, it continues to have a role in otherwise diffi
Methyldopa is a phenylalanine derivative and an aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure.|An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an antihypertensive agent.CertificatesBasic Info-
Product Name:
L-Tyrosine, 3-hydroxy-α-methyl-, hydrate (2:3)
Other Name:L-Tyrosine,3-hydroxy-α-methyl-,hydrate (2:3);(-)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine sesquihydrate
CAS No.:41372-08-1
Molecular Formula:C10H13NO4.3/2H2O
InChIKeys:InChIKey=XDJUBZFLFDODNF-PPHPATTJSA-N
Molecular Weight:229.23
Exact Mass:476.20061
EC Number:209-089-2
UNII:56LH93261Y
DSSTox ID:DTXSID5020863
NCI Thesaurus Code:C47616
HScode:2922504500
Categories:
Characteristics-
PSA:
113.01000
XLogP3:0.13
Appearance:White Solid
Density:1.4±0.1 g/cm3
Melting Point:>300 °C(lit.)
Boiling Point:441.6±45.0 °C at 760 mmHg
Flash Point:220.9±28.7 °C
Refractive Index:1.635
Water Solubility:0.1-1 g/100 mL at 23 ºC
Storage Conditions:Refrigerator
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
EXCIPIENTS,POVIDONE,AMINO ACIDS,API,VITAMINS
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Location:
5th Floor, No.35, Lane 100, Banxia Rd. Pudong New District, Shanghai
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
180 days
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Total Annual Revenue:
$25 million-$50 million
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Total Employees:
51-100
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Year of Establishment:
2005
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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