Factory Price Pharmaceutical Chemical Purity Degree 99% GS-441524
TDS 48 Inquiries
1191237-69-0
Pharmaceutical Grade
99%
SHANGHAI
/
100g
2024-05-18
Pharmaceutical materials (APIs),Pharmaceutical Intermediates,Fine chemicals,Biochemical reagents
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceGS-441524 is a nucleoside analogue that terminates the RNA chain of viral RNA-dependent RNA polymerase. GS-441524 was developed by Gilead Sciences, Inc as part of their research into human RNA virus disease such as Ebola. GS-441524 is a small molecule that exhibits potent antiviral activity against a number of RNA viruses, including the zoonotic severe acute respiratory syndrome (SARS) coronavirus ( Cho et al., 2012).
GS-441524 is a C-nucleoside analog that is (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV. It has a role as a drug metabolite, an antiviral agent and an anticoronaviral agent. It is a pyrrolotriazine, a nitrile, a C-nucleoside and an aromatic amine.|GS-441524 is an adenosine nucleotide analog antiviral, similar to [remdesivir]. This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent. GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a coronavirus that only infects cats.CertificatesBasic Info-
Product Name:
GS-441524
Other Name:(2R,3R,4S,5R)-2-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furancarbonitrile;GS-441524;GS441524;(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile;GS-441524 solution;EVO984;EVO 984;EVO-984;GS 441524
CAS No.:1191237-69-0
Molecular Formula:C12H13N5O4
InChIKeys:BRDWIEOJOWJCLU-LTGWCKQJSA-N
Molecular Weight:291.26
Exact Mass:291.096754
UNII:1BQK176DT6
Categories:
Characteristics-
PSA:
150
XLogP3:-1.27552
Density:1.84±0.1 g/cm3(Predicted)
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical materials (APIs),Pharmaceutical Intermediates,Fine chemicals,Biochemical reagents
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Location:
Room 601, Building 4,No.571, Str.19, Hangzhou, Zhejian
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment
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Average lead Time:
20 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
11-50
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Year of Establishment:
2013
Company Certificates-
Hazardous Chemicals Production License
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Business license
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Inquiry History48 Inquiries
Country Product Purchase Quantity Date Posted
Turkey
GS441524 powder CAS 1191237-69-0 Remdesivir GS-5734 Alprostadil pge
1 PCS Jan 6, 2026
Bulgaria
Lowest price in the whole network 1191237-69-0 GS-441524
100 BOU Nov 8, 2023
United States
GS441524 CAS 1191237-69-0 Cat Fip GS441 liquid 20mg 30mg 6ml 8ml 10ml
4 MT Oct 18, 2023
China
GS 441524
1 KG Dec 5, 2023
United States
GS 441524
30 MG Aug 3, 2026
United States
GS-441524
100 MT Jul 9, 2026
Poland
GS441524 powder
200 G Mar 11, 2026
United States
gs441524
100 Feb 10, 2026
South Korea
GS-441524 20mg tablets
3 PCS Feb 5, 2026
Canada
Alprostadil
10 PCS Nov 25, 2025
Portugal
GS-441524
10 G Nov 17, 2025
Germany
Gs 441524 99.9% purity white powder
20 G Mar 30, 2025
Portugal
GS-441524
16 MG Jan 8, 2025
Pakistan
GS-441524
10 G Sep 13, 2024
United States
Gs441524
100 MT Apr 3, 2024
Turkey
GS-441524
100 G Feb 16, 2024
Pakistan
GS-441524
21 MT Feb 11, 2024
United States
gs441524
250 L Dec 28, 2023
United States
GS 441524
10 L Dec 21, 2023
Pakistan
Gs-441524
10 KG Dec 5, 2023 Post an enquiry for this product
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