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TNJONE High quality GMP Certificated 99% Purity Sirolimus Rapamycin 53123-88-9 in Stock

Name: TNJONE High quality GMP Certificated 99% Purity Sirolimus Rapamycin 53123-88-9 in Stock
Brand: TNJONE
SKU: pr2407161042
Price: 15 USD
Availability: InStock

28 Inquiries

Unit Price: Get Latest Price 

CAS No.:

53123-88-9

Grade:

Function

Rapamycin is a triene macrolide antibiotic,which demonstrates anti-fungal,anti-inflammatory,anti-tumor and immunosuppressive
properties.

Rapamycin has been shown to block T-cell activation and proliferation,as well as,the activation of p70 S6 kinase and exhibits strong
binding to FK506 binding proteins.

Rapamycin also inhibits the activity of the protein,mTOR(mammalian target of rapamycin) which functions in a signaling pathway to
promote tumor growth.

Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction
of mTOR with target proteins in this signaling pathway.

Rapamycin (RAPA) is a novel macrolide immunosuppressant is now often used as a transplanted organ to maintain immunity drugs
(especially kidney transplants), to mitigate the immune organ rejection after transplant surgery, but scientists it recently found another
purpose: for the treatment of Alzheimer's disease (senile dementia).

Target of rapamycin (mTOR) as an intracellular kinases pathway abnormalities can induce a variety of diseases. As rapamycin mTOR
inhibitor targeting, to treat with this pathway is closely related to tumors, including renal cell carcinoma, lymphoma, lung cancer,
liver cancer, breast cancer, neuroendocrine carcinoma and gastric cancer

Company Profile

Shop Factory Direct Supply high quality Antibiotic Ceftriaxone sodium Cas104376-79-6-Detailed Image 5

Shaanxi TNJONE Pharmaceutical Co., Ltd is a high-tech enterprise mainly engaged inthe development and sale of pharmaceutical chemical raw materials and relatedproducts.The company has advanced and perfect supporting system,forming advancedchemical synthesis technology, which can quickly meet the individual needs and serialdevelopment from suitable detection to industrial production.Qur business covers morethan 30 countries, most of customers from Europe, Southeast Asia and other countriesin the world, we can guarantee the quality and price. Our enterprise purpose is basedon the market, strengthen strength, take the road of scientific environmental protectionand sustainable development, rely on the country. The company has a strong financialstrength and a good business environment, can provide customers with quality,efficientand fast service.

Our Advantages

1.High quality and competitive price.
2.Free sample for your evaluation.
3.Promptly delivery by well-reputed shipping lines.
4.Trial order is available for testing after samples.
5.We will inform you all the information at every stage in advance.
6.Packaging can gear to buyers' special request.

Our factory

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How to order

Before ordering	Please send what items and what quantity you need
Send quotation	We will send you a quotation in detail with total
Payment ways chosen	Please choose one of the payment way you preferred. Our payment ways: City bank,BTC,Bank wire, Wise,Master Card , Tether
After payment	Please offer shipping address after payment for shipment.
Tracking	We will provide the tracking after goods sent.
Lead time	About 1-5 working days after payment
Shipping time	About 8-15 days door to door
After-sale service	Available always

Basic Info

Product Name:

Rapamycin

Other Name:

Rapamycin;23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine,rapamycin deriv.;Antibiotic AY 22989;[3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone;23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-,[3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-;(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone;AY 22989;(-)-Rapamycin;Sirolimus;SIIA 9268A;Rapamune;Rapammune;RPM;NSC 226080;RAPA;Wy 090217;Cypher;Nab rapamycin;Supralimus;14S-Rapamycin;Cypher Bx Velocity;PNP-sirolimus;DE 109;MS-RO01;MS-RO02;MS-RO03;Perceiva;Rapamysin;SVP-R;1179372-35-0;1189166-54-8;1233221-34-5;1353039-01-6

CAS No.:

53123-88-9

Molecular Formula:

C51H79NO13

InChIKeys:

InChIKey=QFJCIRLUMZQUOT-HPLJOQBZSA-N

Molecular Weight:

914.18

Exact Mass:

914.17

EC Number:

262-640-9

HScode:

2942000000

Categories:

Other Chemical Drugs

Characteristics

PSA:

195

XLogP3:

Appearance:

yellow solid

Density:

1.2±0.1 g/cm3

Melting Point:

183-185 °C

Boiling Point:

973°C at 760 mmHg

Flash Point:

87 °C

Refractive Index:

1.551

Water Solubility:

soluble in DMSO at 50mg/ml or methanol at 25mg/ml. soluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.ethanol: soluble 2 MM

Storage Conditions:

-20°C

Vapor Pressure:

0.56 hPa ( 20 °C)

Toxicity:

LD50 in mice (mg/kg): 600 i.p.; >2,500 orally (Vézina)

Specific rotation:

D25 -58.2° (methanol)

See More Rapamycin Properties 

Hazard Identification

Classification of the substance or mixture

Carcinogenicity, Category 2

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H351 Suspected of causing cancer H361 Suspected of damaging fertility or the unborn child H372 Causes damage to organs through prolonged or repeated exposure
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Rapamycin Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,API,Vitamins,Food Additive

Location:
No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2019

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.

Inquiry History

28 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Supply Medical Grade High Purity Rapamycin Powder CAS 53123-88-9 Rapamycin	100 G	Aug 16, 2023
Hungary	Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity	100 G	Nov 20, 2023
India	Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity	1000 MT	Nov 18, 2023
Germany	Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity	100 G	Sep 7, 2023
United States	TNJONE High quality GMP Certificated 99% Purity Sirolimus Rapamycin 53123-88-9 in Stock	1 G	Jan 1, 2025
United States	Rapamycin Powder	2 KG	Aug 25, 2023
Paraguay	Rapamycin Sirolimus Powder	1 G	Feb 21, 2024
India	Rapamycin	1 MT	Feb 12, 2026
India	Rapamycin	1.00 KG	Jan 26, 2024
United States	Rapamycin	50 MG	Apr 17, 2026
United States	rapamycin	100 G	Sep 27, 2025
Philippines	Rapamycin	5 G	Feb 10, 2025
Australia	Rapamycin	99 KG	Nov 3, 2024
United States	Rapamycin	10 MT	May 22, 2024
Canada	Rapamycin	1 KG	Jan 24, 2025
United States	Rapamycin	1 KG	Nov 27, 2024
United States	rapamycin	1 G	Jul 12, 2024
India	Rapamycin	1 KG	Jun 28, 2024
United States	Rapamycin	1 KG	Apr 14, 2025
Canada	Rapamycin	100 MG	Mar 4, 2025

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Name	Rapamycin
CAS NO.	53123-88-9
purity	99%
Standard packing material	Bag/Box
Appearance	white power
Shelf Life	2Years
storage condition and solubility	Inert atmosphere,at 2-8°C;Sealed in dry,Store in freezer

TNJONE High quality GMP Certificated 99% Purity Sirolimus Rapamycin 53123-88-9 in Stock

Product Description

Seller Information