More than 15 years GMP Factory Suppy 99.5% Eldecalcitol Medical Grad CAS104121-92-8
104121-92-8
Pharmaceutical Grade
99.5%
shanghai
Honour
25kg/drum, customized
2024-08-17
Semaglutide,Tirzepatide,API,Enzyme
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceEldecalcitol (Edirol) was approved in January 2011 by the Japanese Ministry of Health, Labor, and Welfare for the treatment of osteoporosis. Because of vitamin D’s central role in the bone health, vitamin D and analogs of vitamin D have been used to treat patients diagnosed with osteoporosis. Eldecalcitol is an analog of the active form of vitamin D, calcitriol, in which the lower cyclohexane ring contains a hydroxypropyl group. The synthesis of eldecalcitol involves the assembly of two units, a fully protected (3S,4S,5R)-oct-1-en-7-yne-3,4,5-triol and a fused bicyclic system, (R)-6- ((1R,3aR,7aR,E)-4-(bromomethylene)-7a-methyloctahydro-1H-inden-1- yl)-2-methylheptan-2-ol, through a Diels-Alder reaction to give fully protected eldecalcitol. The hydroxyl groups are then deprotected to give the parent molecule. Eldecalcitol binds to the vitaminDreceptor 2.7-fold more potently than calcitriol, while only weakly inhibiting serum parathyroid hormone.
ChEBI: A hydroxycalciol that is calcitriol with a 3-hydroxypropoxy group at position 2.Basic Info-
Product Name:
2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3
Other Name:2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3;Eldecalcitol;ED-71;(1R,Z)-5-((E)-2-((1R,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-2-(3-hydroxypropoxy)-4-methylenecyclohexane-1,3-diol;1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3;Eldecalcitol(ED-71);2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitaMin D3;(1S,2S,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-2-(3-hydroxypropoxy)-4-methylidenecyclohexane-1,3-diol
CAS No.:104121-92-8
Molecular Formula:C30H50O5
InChIKeys:FZEXGDDBXLBRTD-AYIMTCTASA-N
Molecular Weight:490.71
EC Number:686-849-3
Color/Form:White to off-white
Categories:
Characteristics-
Density:
1.10
Melting Point:126-128℃
Boiling Point:655.7±55.0 °C(Predicted)
PKA:13.80±0.60(Predicted)
Critical Temperature & Pressure:Store at -20°C
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Seller Information
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Business Type:
Trader
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Main Products:
Semaglutide,Tirzepatide,API,Enzyme
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Location:
Unit ST-308, No. 329, Jiahe Road, Siming District, Xiamen
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$50 million-$100 million
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Total Employees:
11-50
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Year of Establishment:
2018
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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