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Fezolinetant CAS 1629229-37-3 best quality high purity

Name: Fezolinetant CAS 1629229-37-3 best quality high purity
Brand: Million
SKU: pr2407304817
Price: 2.5 USD
Availability: InStock

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Unit Price:

$2.5/KG EXW

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CAS No.:

1629229-37-3

Grade:

Pharmaceutical Grade

Content:

99.87%

Port:

beijing/shanghai/jinan...

Brand:

Million

Packaging:

25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2100-12-31

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Jinan Million Pharmaceutical Co., Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

L/C,100% TT in advance

Average Lead Time:

3 days

Qualification:

Main Products:

Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

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Product Description
Seller Information
Inquiry History

Description

Shop Apixaban CAS 503612-47-3 FACTORY supply-Detailed Image 1

-Product Descrition-

Description：Fezolinetant is an oral small molecule neurokinin-3 receptor (NK3R) antagonist developed by Astellas Pharma Inc. for the treatment of moderate to severe vasoconstrictive symptoms (VMS) or menopausal hot flashes. Fezolinetant is a non hormonal strategy that regulates neuronal activity related to temperature regulation by inhibiting NK3R mediated signaling in the central nervous system, thereby reducing the frequency and severity of VMS.

Origin：Fezolinetant was first approved in the United States in May 2023 for the treatment of moderate to severe vasoconstrictive symptoms (VMS) caused by menopause.

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 2

Why Choose Us ？

1 、 Manufacturer supply, best price and service.

2、 Safe fast delivery.

3、 F ree sample.

4、 Large stock.

5、 Easy payment: bank transfer, moneygram, paypal....

6、 Good reputation, great feedback.

7、 Customers worldwide: Metrochem Api Pvt Ltd;Bdr Lifesciences Pvt.Ltd;Srini Chem;Eva Pharma;Pharmaffiliates Analytics&Synthetics(p)Ltd;....From India,Egypt,Canada ....

-Packing&Shipping-

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 3

Ship methods	Special line	Express	By air	By sea
Ship methods	Special line	DHL/TNT/FeDex/UPS	By air	By sea
Delivery	7-15 days	3-10 days	3-5 days	10-30 days
Service	Door to door	Door to door	To airport	To seaport
Customs clearance	No	Possible	Yes	Yes

-Company Profile-

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 4

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 5

About us:

Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.

Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixab a n, Lurasidon e , Bexagliflozin, Vortioxetine, L OXO -292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...

Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.

The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.

Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.

-Certification- Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 6

ECHEMI Editorial Reference

Fezolinetant is under investigation in clinical trial NCT04234204 (A Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women in Asia Going Through Menopause).
ChEBI: Fezolinetant is a triazolopyrazine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine substituted by 3-methyl-1,2,4-thiadiazol-5-yl, 4-fluorobenzoyl and methyl groups at positions 3, 7, and 8R, respectively. It is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause. It has a role as a neurokinin-3 receptor antagonist. It is a member of monofluorobenzenes, a triazolopyrazine, a member of thiadiazoles, a member of benzamides and a tertiary carboxamide.

Certificates

Basic Info

Product Name:

Fezolinetant

Other Name:

FEZOLINETANT; ESN-364; ESN 364; ESN364;ESN-364;Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-;Inhibitor,Neurokinin Receptor,ESN364,Tachykinin receptor,ESN 364,Fezolinetant,inhibit,NK receptor;(R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone;Fexolinetant;Fezolinetant;(S)-1-((2-((tert-butyldimethylsilyl)oxy)ethyl)amino)-2,3-dihydro-1H-indene-4-carbonitrile

CAS No.:

1629229-37-3

Molecular Formula:

C16H15FN6OS

InChIKeys:

PPSNFPASKFYPMN-SECBINFHSA-N

Molecular Weight:

358.39

Exact Mass:

358.10120846

UNII:

83VNE45KXX

Color/Form:

White to yellow

Categories:

Other Chemical Drugs

Characteristics

Density:

1.56±0.1 g/cm3(Predicted)

Boiling Point:

623.0±65.0 °C(Predicted)

PKA:

-0.28±0.40(Predicted)

Critical Temperature & Pressure:

Store at -20°C

Seller Information

Business Type:
Manufactory

Main Products:
Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

Location:
Room 1-2208, Lianhecaifu Square, No2177, Tianchen Road, Gaoxin District, Jinan City, Shandong Province, China

Payment Terms:
L/C,100% TT in advance

Average lead Time:
3 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2012

Company Certificates
- business license
Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.

Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixaban, Lurasidone, Bexagliflozin, Votioxitine, Loxo-292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; INCETPAT PHARM; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...

Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.

The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.

Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	FEZOLINETANT	450 G	Feb 14, 2025
Bangladesh	Fezolinetant	50 KG	Dec 31, 2024

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Fezolinetant CAS 1629229-37-3 best quality high purity

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