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More than 15 years GMP Factory Suppy 99.5% Methyldopa Medical Grade CAS555-30-6

Name: More than 15 years GMP Factory Suppy 99.5% Methyldopa Medical Grade CAS555-30-6
Brand: Honour
SKU: pr2409251467
Price: 10 USD
Availability: InStock

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CAS No.:

555-30-6

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

shanghai

Brand:

Honour

Packaging:

25kg/drum, customized

Price valid (until):

2024-10-25

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Honour Enterprise Company Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Semaglutide,Tirzepatide,API,Enzyme

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Product Description
Seller Information
Inquiry History

Description

We provide technical support, free sample and custom synthesis service, fast,safe and reliable delivery.

Contact us for the most sincere service:

Sales2@honourchina.com

Whatsapp: +86 18020752052

Wechat: honourchem

Skype: julie.chan81

Product Detail

Identification

Name	Methyldopa
Synonyms	2-Amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid; L-Methyl Dopa
Cas number	555-30-6
EC number	209-089-2
Formula	C₁₀H₁₃NO₄
molecule weight	211.22
Appearance	Solid

Package

Can be packaged according to customer requirements

Application

It is used for pharmaceutical intermediateds.

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ECHEMI Editorial Reference

Methyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.Target: alpha-adrenergic agonistMethyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents. However, it continues to have a role in otherwise difficult to treat hy
Methyl dopa appears as colorless or almost colorless crystals or white to yellowish-white fine powder. Almost tasteless. In the sesquihydrate form. pH (saturated aqueous solution) about 5.0. (NTP, 1992)|Solid
Methyl dopa appears as colorless or almost colorless crystals or white to yellowish-white fine powder. Almost tasteless. In the sesquihydrate form. pH (saturated aqueous solution) about 5.0. (NTP, 1992)|Alpha-methyl-L-dopa is a derivative of L-tyrosine having a methyl group at the alpha-position and an additional hydroxy group at the 3-position on the phenyl ring. It has a role as a hapten, an antihypertensive agent, an alpha-adrenergic agonist, a peripheral nervous system drug and a sympatholytic agent. It is a L-tyrosine derivative and a non-proteinogenic L-alpha-amino acid.|Methyldopa anhydrous is a Central alpha-2 Adrenergic Agonist. The mechanism of action of methyldopa anhydrous is as an Adrenergic alpha2-Agonist.|Methyldopa (alpha-methyldopa or α-methyldopa) is a centrally active sympatholytic agent that has been used for more than 50 years for the treatment of hypertension. Methyldopa has been clearly linked to instances of acute and chronic liver injury that can be severe and even fatal.|An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an antihypertensive agent.

Basic Info

Product Name:

Methyldopa

Other Name:

L-Tyrosine,3-hydroxy-α-methyl-;Alanine,3-(3,4-dihydroxyphenyl)-2-methyl-,L-;3-Hydroxy-α-methyl-L-tyrosine;MK 351;Nr.C 2294;Aldomet;Levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine;L-(-)-β-(3,4-Dihydroxyphenyl)-α-methylalanine;L-α-Methyl-3,4-dihydroxyphenylalanine;L-(-)-α-Methyl-β-(3,4-dihydroxyphenyl)alanine;Methyldopa;α-Methyl-L-3,4-dihydroxyphenylalanine;Presinol;(-)-α-Methyl-3,4-dihydroxyphenylalanine;l-3-(3,4-Dihydroxyphenyl)-2-methylalanine;Dopegyt;α-Methyldopa;(-)-Methyldopa;l-α-Methyldopa;α-Methyl-L-dopa;(S)-(-)-α-Methyldopa;L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid;AMD;Aldometil;Aldomin;Dopamet;Sembrina;Dopatec;Medomet;Medopren;Methoplain;Alpha medopa;Bayer 1440L;Baypresol;Presolisin;Alphamethyldopa;2-Methyl-3-(3,4-dihydroxyphenyl)alanine;(-)-α-Methyldopa;L-3,4-Dihydroxyphenyl-2-methylalanine;(S)-α-Methyldopa;Methyl-L-dopa;L-α-Methyldopa;L-3,4-Dihydroxy-α-methylphenylalanine;L-Methyldopa;L-α-Methyl-3-(3,4)-dihydroxyphenylalanine;Equibar;Aldomine;Medopa;Lederdopa;Elanpres;NSC 169916;Aldochlor;(2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;133161-54-3;779-08-8;1339-75-9;4290-08-8;88620-56-8

CAS No.:

555-30-6

Molecular Formula:

C10H13NO4

InChIKeys:

InChIKey=CJCSPKMFHVPWAR-JTQLQIEISA-N

Molecular Weight:

211.21

Exact Mass:

211.21

EC Number:

209-089-2

UNII:

M4R0H12F6M

NSC Number:

760080

DSSTox ID:

DTXSID5020863|DTXSID5023295

Color/Form:

Minute, anhyd crystals from methanol|WHITE TO YELLOWISH WHITE, FINE POWDER, WHICH MAY CONTAIN FRIABLE LUMPS

ATC Code:

C - Cardiovascular system

HScode:

2918199090

Categories:

Characteristics

PSA:

104

XLogP3:

-1.79

Appearance:

Methyl dopa appears as colorless or almost colorless crystals or white to yellowish-white fine powder. Almost tasteless. In the sesquihydrate form. pH (saturated aqueous solution) about 5.0. (NTP, 1992)

Density:

1.4±0.1 g/cm3

Melting Point:

300 °C (decomp)

Boiling Point:

441.6±45.0 °C at 760 mmHg

Flash Point:

220.9±28.7 °C

Refractive Index:

1.635

Water Solubility:

H2O: 10g/L(temperature not stated)

Storage Conditions:

Store at RT

Toxicity:

LD50 oral in rabbit: 713mg/kg

Specific rotation:

Max absorption: 281 nm (e= 2780); Specific optical rotation (1 in 0.1 N HCl): -4.0 +/- 0.5 deg @ 23 °C/D

Odor:

ODORLESS

Taste:

ALMOST TASTELESS

PH:

pH of saturated aq soln about 5.0

Collision Cross Section:

147.6 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|146.8 Å² [M+Na]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

Considerably hygroscopic; decomp @ approx 300 °C; exists as sesquihydrate|Crystals from water /sesquihydrate/

Air and Water Reactions:

Very hygroscopic. Slightly water soluble. May be sensitive to prolonged exposure to air and light. The stability of aqueous solutions is markedly dependent on pH, oxygen and the amount of initial reactant. Aqueous solutions are stable for up to 50 hours in acid and neutral pH (6.2). At pH 8.0, decomposition products are formed in 3 to 5 hours. Solutions develop a red tint that becomes progressively darker (eventually forming a black precipitate).

Reactive Group:

Acids, Carboxylic

Reactivity Profile:

METHYL DOPA undergoes catalytic oxygenation in the presence of magnesium, cupric, cobalt, nickel and ferric ions (NTP, 1992). A weakly acidic amino acid.

See More Methyldopa Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Methyldopa oral suspension should be stored in tight, light-resistant containers at a temperature less than 26 deg C and protected from freezing. Methyldopa tablets should be stored in well-closed containers at a temperature less than 40 deg C, preferably at 15-30 deg C.

See More Methyldopa Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Semaglutide,Tirzepatide,API,Enzyme

Location:
Unit ST-308, No. 329, Jiahe Road, Siming District, Xiamen

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$50 million-$100 million

Total Employees:
11-50

Year of Establishment:
2018

Honour Enterprise Company Limited, found in 2008, specialized in R&D, manufacture and export various of fine chemicals. We are one of the leading export corporation in China.We have enjoyed good reputation in the world market for a long time,because of the competitive price, excellent quality, delivery immediate on time, we are received the extensive favorable comment of the foreign customer deeply. R&D Center One of the benefits of the long-term relationships we develop with our clients is in the new product development area,our products are well sold in America, Europe,Japan, Singapore, South Korea.

AfteAfter years of development, our company has accumulated abundant products resources in local China and international market which increasingly satisfy development requirements of customers. The products includes fine chemicals, food additives, feed additives, Pharmaceutical intermediates, pesticides, dyes and pharmaceutical and monomer for contact lens material custom synthesis is also available.

Our vision is to supply our customers with the highest quality ingredients with competitive price and excellent service through our professional knowledge. We will achieve our vision by working closely with our partners from all over the world.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	Methyldopa	2000 KG	Sep 13, 2023
Pakistan	Methyldopa	75 KG	Sep 11, 2023

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More than 15 years GMP Factory Suppy 99.5% Methyldopa Medical Grade CAS555-30-6

Product Description

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