High Quality 99% Canagliflozin CAS 842133-18-0 Powder Fast Shipping Best Price

Canagliflozin More Info

Canagliflozin is an oral medication that belongs to the class of drugs known as sodium-glucose cotransporter-2 (SGLT2) inhibitors. It is primarily used for the management of type 2 diabetes mellitus. By inhibiting the SGLT2 protein in the kidneys, canagliflozin reduces the reabsorption of glucose, leading to increased glucose excretion in the urine and consequently lowering blood glucose levels.

The mechanism of action involves the prevention of glucose reabsorption in the proximal convoluted tubule of the nephron, which results in lower plasma glucose levels. This effects not only contribute to glycemic control but may also assist in weight loss and lowering blood pressure, making it a beneficial option for many patients with type 2 diabetes, especially those who are overweight or have hypertension.

Canagliflozin is typically prescribed in conjunction with diet and exercise to improve glycemic control. It can be used alone or in combination with other antidiabetic agents, including metformin, sulfonylureas, or insulin, depending on the individual patient’s needs.

Common side effects associated with canagliflozin include urinary tract infections, genital mycotic infections, increased urination, and dehydration. Patients may also experience side effects such as dizziness, hypotension, and acute kidney injury. Due to its mechanism of action, there is also an increased risk of diabetic ketoacidosis, which is a serious condition that must be monitored for in patients.

It is important for healthcare providers to assess a patient's renal function before initiating treatment with canagliflozin, as the drug is contraindicated in patients with severe renal impairment or end-stage renal disease. Additionally, the use of canagliflozin in pregnant or breastfeeding women should be approached with caution, as there is insufficient data on its safety in these populations.

In recent studies, canagliflozin has also shown cardiovascular benefits. Clinical trials have indicated that it may reduce the risk of cardiovascular events in patients with established cardiovascular disease or at high risk. This highlights its dual role in managing not only blood glucose levels but also long-term cardiovascular health.

In summary, canagliflozin is an SGLT2 inhibitor used to manage type 2 diabetes mellitus by promoting glucose excretion through the urine. It offers additional benefits such as weight loss and potential cardiovascular protection, but its use requires careful consideration of renal function and monitoring for side effects. A comprehensive evaluation by a healthcare provider is essential to ensure its appropriateness for individual patients.

Product Image

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders:
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.