Supply High Quality Antiparasitic Drug Ivermectin CAS 70288-86-7 White Raw Material Powder

Ivermectin More Info

Ivermectin is an antiparasitic medication widely used to treat various parasitic infections in both humans and animals. 

Mechanism of Action

Ivermectin functions by interfering with the neuromuscular function of parasites. It binds to glutamate-gated chloride channels found in invertebrate nerve and muscle cells. This binding causes an influx of chloride ions, leading to hyperpolarization of the cell membranes, paralysis, and ultimately death of the parasites. Ivermectin is selective for invertebrates due to the limited presence of these channels in mammals, which helps to minimize toxicity in human patients

Applications

Ivermectin is approved for a variety of uses:
Parasitic Infections: It is primarily used to treat infections caused by parasitic worms such as:
Onchocerciasis (river blindness)
Strongyloidiasis
Ascariasis
Trichuriasis
Filariasis
Ectoparasitic Infections: It is effective against external parasites such as lice (pediculosis) and scabies.
Antiviral Activity: Emerging research suggests that ivermectin may have antiviral properties against certain RNA and DNA viruses, including dengue and Zika virus.

Routes of Administration

Ivermectin can be administered through several routes:
Oral Tablets: The most common form for treating systemic infections. Dosage is typically based on body weight.
Topical Formulations: Creams or lotions are available for treating localized infestations like scabies.
Injectable Forms: Used primarily in veterinary medicine but also applicable in certain human treatments.

Safety and Side Effects

Ivermectin is generally well tolerated, but some side effects may occur:
Common Side Effects: These can include dizziness, nausea, diarrhea, fatigue, and skin rashes.
Severe Reactions: In rare cases, it may cause neurological symptoms such as seizures or confusion, particularly if overdosed or used improperly.
Contraindications: Caution is advised for individuals with liver disease or those who are pregnant or breastfeeding.

Pharmacokinetics

The pharmacokinetics of ivermectin involve several key aspects:
Absorption: Ivermectin is well absorbed when taken orally; however, its absorption can be enhanced when taken with food. The oral solution has higher bioavailability compared to tablets.
Distribution: It distributes widely throughout the body but does not readily cross the blood-brain barrier due to P-glycoprotein activity. This limits potential central nervous system toxicity.
Metabolism: Ivermectin is metabolized primarily by the liver enzyme CYP3A4 into several metabolites, some of which retain activity against parasites. The elimination half-life varies but is generally around 12 hours for the parent compound.
Excretion: Metabolites are excreted mainly through feces and urine.

Package Image

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.