China Supplier Factory Direct Supply high quality Gemcitabine Hydrochloride 122111-03-9 with good price
TDS 1 Inquiries
122111-03-9
Pharmaceutical Grade
99%
qingdao
HM
1 g,10g,50g or according to customer's detail requirement.
Yes
2025-04-30
Propylene glycol
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceSuitable for the treatment of inoperable advanced or metastatic pancreatic cancer and the treatment of locally advanced or metastatic non-small cell lung cancer, the treatment of intermediate and advanced non-small cell lung cancer, non-small cell lung cancer, pancreatic cancer, bladder cancer, breast cancer and Other solid tumors.
Gemcitabine Hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis.Certificates-
TDS
Basic Info-
Product Name:
Gemcitabine hydrochloride
Other Name:Cytidine,2′-deoxy-2′,2′-difluoro-,hydrochloride (1:1);Cytidine,2′-deoxy-2′,2′-difluoro-,monohydrochloride;LY 188011 hydrochloride;Gemcitabine hydrochloride;Gemzar;Gemsar;Gemcitera;GEMORAL;2′-Deoxy-2′,2′-difluorocytidine monohydrochloride
CAS No.:122111-03-9
Molecular Formula:C9H11F2N3O4.ClH
InChIKeys:InChIKey=OKKDEIYWILRZIA-OSZBKLCCSA-N
Molecular Weight:299.66
Exact Mass:299.048431
EC Number:1308068-626-2
UNII:U347PV74IL
DSSTox ID:DTXSID3047849
NCI Thesaurus Code:C961
HScode:2934999090
Categories:
Characteristics-
PSA:
108
XLogP3:0.09460
Appearance:White crystalline granular, odorless
Melting Point:287-292 °C
Boiling Point:482.7ºC at 760 mmHg
Flash Point:245.7ºC
Water Solubility:H2O: ≥10mg/mL
Storage Conditions:Desiccate at +4°C
Vapor Pressure:2.41E-11mmHg at 25°C
Specific rotation:D +48°; 365 +257.9° (c = 1.0 in deuterated water)
Hazard IdentificationClassification of the substance or mixture
Reproductive toxicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H360 May damage fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Propylene glycol
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Location:
No .41 Optics Valley Avenue, East Lake High-tech Development Zone, Wuhan ,China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment
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Average lead Time:
5 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2024
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
United Kingdom
Gemcitabine hydrochloride
500 G Dec 1, 2023 Post an enquiry for this product
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