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CALCIFEDIOL, 63283-36-3, Vitamin D Analog, Bone Metabolism Regulator, Pharmaceutical Intermediate

Name: CALCIFEDIOL, 63283-36-3, Vitamin D Analog, Bone Metabolism Regulator, Pharmaceutical Intermediate
Brand: HyperChem
SKU: pr2502041015
Price: 550 USD
Availability: InStock

COA 8 Inquiries

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CAS No.:

63283-36-3

Grade:

Pharmaceutical Grade

Content:

98%

Port:

Shanghai

Brand:

HyperChem

Packaging:

aluminium foilbag, bottle, vial

Price valid (until):

2025-03-04

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Product Description: CALCIFEDIOL (63283-36-3)

Product Overview

CALCIFEDIOL (CAS No. 63283-36-3) is a high-purity Vitamin D analog and a key intermediate in pharmaceutical research and production. It plays a vital role in regulating calcium and phosphate metabolism, making it essential for bone health and the treatment of metabolic bone disorders.

Key Features

High Purity: Meets EP8.0 standards with a purity of 97.0%-102.0%.
Appearance: White or almost white crystalline powder.
Solubility: Practically insoluble in water, freely soluble in ethanol (96%), and soluble in fatty oils.
Stability: Stable under recommended storage conditions.

Applications and Uses

Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) for treating vitamin D deficiency and related disorders.
Bone Health: Regulates calcium and phosphate absorption, supporting bone metabolism and preventing osteoporosis.
Research and Development: Widely used in biochemical research and clinical studies related to vitamin D metabolism.

Specifications and Quality Standards

Parameter	Specification	Result
Assay	97.0% - 102.0%	Complies
Appearance	White or almost white crystals	Complies
Solubility	Soluble in ethanol, fatty oils; insoluble in water	Complies
Related Substances	Total impurities ≤1.0%	Complies
Water Content	3.8% - 5.0%	Complies
Identification (IR/HPLC)	Matches reference standard	Complies

Packaging and Storage

Packaging: Available in 100mg units, securely packed to ensure stability and prevent contamination.
Storage: Store in a cool, dry place at 2-8°C, protected from light and moisture.
Shelf Life: 24 months from the manufacturing date (see batch-specific COA for details).

Why Choose Our CALCIFEDIOL?

Quality Assurance: Strict adherence to EP8.0 standards and comprehensive COA provided.
Reliable Supply: Consistent production and timely delivery.
Technical Support: Expert guidance available for product selection and application.

ECHEMI Editorial Reference

Calcifediol (monohydrate) is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM).

Research & Reference Note

CALCIFEDIOL, 63283-36-3, Vitamin D Analog, Bone Metabolism Regulator, Pharmaceutical Intermediate is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Authoritative sources

Disclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals

Certificates

Basic Info

Product Name:

Calcifediol

Other Name:

Calcifediol /25-Dihydroxyvitamin D3;25-OH-VD3;Calcifediol/25-Hydroxycholecalciferol H20;CALCIDIOL;CALCIFEDIOL;CALCIFEDIOL MONOHYDRATE;25-OH-D3;25-HYDROXYVITAMIN D3

CAS No.:

63283-36-3

Molecular Formula:

C27H44O2

InChIKeys:

WRLFSJXJGJBFJQ-WPUCQFJDSA-N

Molecular Weight:

400.64

Exact Mass:

418.344695 g/mol

EC Number:

242-990-9

HScode:

29362900

Categories:

Skeletal Muscle Relaxants

Characteristics

PSA:

40.46000

XLogP3:

6.73390

Appearance:

brownish, fine powder

Boiling Point:

529.2ºC at 760 mmHg

Flash Point:

14℃

Storage Conditions:

−20°C

Vapor Pressure:

2.07E-13mmHg at 25°C

See More Calcifediol Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 2, Oral

Acute toxicity - Category 2, Dermal

Acute toxicity - Category 1, Inhalation

Specific target organ toxicity â repeated exposure, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H300 Fatal if swallowed H310 Fatal in contact with skin H330 Fatal if inhaled H372 Causes damage to organs through prolonged or repeated exposure
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P316 Get emergency medical help immediately. P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label). P319 Get medical help if you feel unwell.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Calcifediol Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- Certification Report by Bureau Veritas
About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

8 Inquiries

Country	Product	Purchase Quantity	Date Posted
Bahamas	Pharmaceutical grade calcifediol 63283-36-3	1 KG	Feb 6, 2025
Romania	Calcifediol Monohydrate;	1 KG	Mar 5, 2025
Germany	Calcifediol	1 KG	Jan 4, 2026
Nigeria	Calcifediol Monohydrate	20 MG	May 9, 2025
Nigeria	Calcifediol Monohydrate	1 KG	Apr 21, 2025
Bahamas	Calcifediol	4000 MG	Feb 4, 2025
Finland	Calcifediol monohydrate 99%	2 KG	Jan 20, 2025
France	Calcifediol	100 KG	Jan 16, 2025

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