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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Upadacitinib for Sale > Hot sale Upadacitinib CAS 1310726-60-3 safe transportation
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Hot sale Upadacitinib CAS 1310726-60-3 safe transportation

TDS 13 Inquiries

Unit Price:

$1/KG FOB

Get Latest Price
CAS No.:

1310726-60-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

China

Brand:

JY

Packaging:

Aluminum foil bag

Sample Available:

Yes

Price valid (until):

2031-12-31

Company Type:
Trader
Location:
Hongkong, China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Qualification:
Main Products:

Peptides

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    High quality supplier, top!


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    Our guarantee:
    Accurate content and safe transportation. Any accident guaranteed money back! High purity, reliable quality, 100% safety. Lost in the customs inspection process, immediately arrange replacement!


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    "High quality products, cost-effective price, stable supply, fast delivery, better reputation, professional service" is our company's business purpose. We sincerely hope to establish stable, strategic and long-term business relationships with domestic and foreign suppliers and customers, and jointly pursue a better future.
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    Our advantage

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    Q&A

    Q1: After-sales service of products

    A: After purchasing products from our factory, we have a professional technical team and after-sales team to serve you and solve all your problems in the future

    Q2: Can I get some samples?

    A: Yes, we can provide samples, but the customer will pay for shipping.

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    Shipping

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    Suitable for under 50 kg, fast: 3-4 days. High cost; Door to door service. Easy pick-up.

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    Suitable for more than 50 kg, fast: 4-5 days. High cost: Airport to airport professional broker required

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    ECHEMI Editorial Reference
    Upadacitinib is a JAK1 inhibitor (IC50= 47 nM). It is selective for JAK1 over JAK3 and tyrosine kinase 2 (Tyk2; IC50s = 2,304 and 4,690 nM, respectively), as well as a panel of 83 additional kinases at 1 μM, but does inhibit JAK2, Rho-associated kinase I (ROCK1), and ROCK2 (IC50s = 120, 920, and 430 nM, respectively). Upadacitinib decreases cytokine-induced STAT phosphorylation in a variety of human cells with IC50values ranging from 1.6 to 649 nM. It reducesM. tuberculosis-induced paw swelling and bone erosion in a rat model of arthritis when administered at doses of 1, 3, and 10 mg/kg twice per day for 17 days. Formulations containing upadacitinib have been used in the treatment of rheumatoid arthritis.
    Upadacitinib was discovered by AbbVie scientists, RINVOQ is a JAK inhibitor that is being studied in several immune-mediated inflammatory diseases. In human leukocyte cellular assays, RINVOQ inhibited cytokine-induced STAT phosphorylation mediated by JAK1 and JAK1/JAK3 more potently than JAK2/JAK2 mediated STAT phosphorylation. Upadacitinib (RINVOQ) received FDA approval in 2019 for the treatment of moderate to severe RA.

    Certificates
    • Hot sale Upadacitinib CAS 1310726-60-3 safe transportation Certificates 1 TDS

    Basic Info
    Product Name:

    Upadacitinib

    Other Name:

    Upadacitinib;Upadacitinib (ABT-494);ABT-494 (Upadacitinib);Upadacitinib (Rinvoq);ABT-494; ABT494; ABT 494;CS-2730;(3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, Upadacitinib;1-Pyrrolidinecarboxamide, 3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)-, (3S,4R)-

    CAS No.:

    1310726-60-3

    Molecular Formula:

    C17H19F3N6O

    InChIKeys:

    WYQFJHHDOKWSHR-MNOVXSKESA-N

    Molecular Weight:

    380.37

    Exact Mass:

    380.37

    EC Number:

    213-161-9

    Color/Form:

    White to off-white

    Characteristics
    PSA:

    78.32

    XLogP3:

    3.2367

    Density:

    1.56±0.1 g/cm3(Predicted)

    PKA:

    11.89±0.60(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides

    Location:

    Room 5003, 5th Floor, Yau Lee Centre, 45 Yuen Yuen Road, Kwun Tong, Hong Kong

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2024

  • Inquiry History
    13 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Upadacitinib

    30.00 KG May 20, 2024
    India

    Upadacitinib - ABT- 494

    5.00 KG Jan 19, 2024
    India

    Upadacitinib

    5 KG Jan 17, 2024
    India

    Upadacitinib

    10.00 KG Mar 6, 2024
    Hongkong, China

    Upadacitinib

    50 MG Apr 7, 2026
    India

    Upadacitinib

    100 G Nov 24, 2025
    India

    Upadacitinib

    5 KG Nov 29, 2023
    Pakistan

    Upadacitinib

    1 KG Feb 17, 2025
    Pakistan

    UPADACITINIB

    0.51 KG Feb 25, 2026
    India

    Upadacitinib

    1000.00 KG Feb 13, 2025
    India

    URSODEOXYCHOLIC ACID

    10.00 KG Mar 6, 2024
    India

    Acarbose

    10.00 KG Mar 6, 2024
    India

    Ripretinib

    10.00 KG Mar 6, 2024
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