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Semaglutide 782487-28-9 High Quality and Competitive Price for API Door to door service

Name: Semaglutide 782487-28-9 High Quality and Competitive Price for API Door to door service
Brand: First Chems Co., LTD
SKU: pr2503311273
Price: 25 USD
Availability: InStock

GMP HALAL KOSHER ISO FDA

Unit Price:

$25-30/MT FOB

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CAS No.:

782487-28-9

Grade:

Chemical Grade

Content:

99%

Port:

qingdao

Brand:

First Chems Co., LTD

Packaging:

10mg/vial,15mg/vial,10vials/box

Sample Available:

Yes

Price valid (until):

2026-12-31

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First Chems Co., LTD

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

Titanium dioxide,npk,pvc,sles,labsa,mdi

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Product Description
Seller Information

Description

Product Detail

What is Semaglutide ?

Semaglutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2017. The peptide is chemically similar to liraglutide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans.

Function

1.Weight loss
2. Anti-diabetes
3. Alzheimer's disease.

Application

Semaglutide injection (We-govy) is used along with an individualized low-calorie, low-fat diet and exercise program to help with weight loss in overweight adults who may also have high blood pressure, diabetes, or high cholesterol. Semaglutide injection is in a class of medications called incretin mimetics. It works by helping the pancreas to release the right amount of insuli when blood sugar levels are high. Insuli helps move sugar from the blood into other body tissues where it is used for energy. Semaglutide injection also works by slowing the movement of food through the stomach and may decrease appetite and cause weight loss.

Products Name: Semaglutide
CAS No.: 910463-68-2
Purity: >99.0%
Molecular Formula: C187H291N45O59
Molecular Weight: 4113.64g/mol
Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(C18diacid-γ-Glu-OEG-OEG)]-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
Appearance: White Lyophilized powder

Other Names	weight loss slimming Powder
MOQ	1 box
Place of Origin	China
Usage	weight loss & slimming
Purity	99.99%
Model Number	JK0662
Form	powder
Color	white powder
Sample	Availiable

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Application Area

1. Triethyl citrate is a non-toxic plasticizer, widely used in cellulose resin and vinyl resin plasticizer,

2. As a bulking preservative in food, it can improve the foaming property of baked food and improve the bulking state.
3. Used as an antioxidant to stabilize soybean oil, salad oil, margarine, shortening and other edible oils,
4. As a flavor enhancer, it can be used in soft drinks, candy, baked goods to increase flavor, and is also used as a chelating agent and carrier solvent.
5. Especially suitable for ink coating, non-toxic PVC granulation, pharmaceutical industry, children's soft toys, medical products, preparation of flavors and spices, cosmetics manufacturing and other industries.

Company profile

First Chems Co., LTD is an enterprise mainly in engaged in researching, producing and saling new-born API. Our company is located in Shijiazhuang city,Hebei province.
We have many years of professional experiences and a professional team of scientists and advanced equipments. Nowadays we formed a large varieties large scale, complete categories and high technology content product chain. Our quality system has been accredited by SGS and our quality center guarantees quality with full documentation control and complete facilities.
Based on the good quality, pretty competitive price and safe delivery our products are widely exported to many different countries, like Netherlands, Spain, UK, USA and so on. And our products are highly recognized by customers around the world, so we can build long-term cooperative relationship with many pharmaceutical enterprises in the world. We upload the principles of openness and transparency and dedicated to provide efficient and high quality services to every customer. We are sincerely looking forward to establishing a long-term stable and win-win business relationship with every customer.

Packing and Shipping

Our Advandage

1.High quality --Coming from good materials and high technology.
2.Lower price--Not cheapest but the lowest at the same quality.
3.Good service--Satisfactory service before and after sale.4.We have our own warehouses in Australia, the United States, Germany, Canada and other countries, which greatly saves shipping time and customers can receive their packages faster. In addition, customers can also choose door-to-door pickup service.

FAQ

Q: How to order this product?
A: You can click "contact now" , and send us a inquiry, leave your number if possible, we will contact with you as soon as possible, then we can talk order details.
Q: How long can I receive my ordered goods?
A: We ship by express door to door; you can receive it in 7-10 days.
Q: What liquid should I add into the vial? And how much liquid needed?
A: You can add sterile water or saline, 1 vial add 1ml liquid is ok.
Q: Will I have any side effects after using peptide?
A: If you just begin to use, it is better to follow doctor's prescription. And if there is no allergy or any uncomfortable symptom, you can continue to use but take it in a suitable dosage. A few people will have slight allergy reaction, but after your body get used to it, the allergy will be disappear and back to normal.
Q: How to store it?
A: If it hasn't been opened, just put it in cool dry place, if it is opened, you may put it in cold storage for 2-5 degree condition.

Certificates

Basic Info

Product Name:

Rosiptor

CAS No.:

782487-28-9

Categories:

Bulk Drug Intermediates

Research

Class:

GLP-1R agonist

Status:

FDA-approved (Ozempic / Wegovy / Rybelsus)

Mechanism:

Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

Activity note:

Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

Source:

Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

Clinical Development:

NCT03548935; NCT03552757; NCT01720446; NCT02692716

FDA:

Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)

Disclaimer:

Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

Seller Information

Business Type:
Trader

Main Products:
Titanium dioxide,npk,pvc,sles,labsa,mdi

Location:
37 Keji Road, Yanta District, Xi 'an City, Shaanxi Province

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
Less than 5

Year of Establishment:
2020

COMPANY OVERVIEW

First Chems Co., LTD，a joint-stock enterprise with production, export and services of chemicals, has widely adopted world-advanced equipments and management system, and our products quality is assured under the ISO9001 and ISO14001 standards, mainly specializes in developing Agriculture/Fertilizer chemicals series, Washing detergent chemicals series, Soda alkali chemicals series, Water treatment chemical series, etc.

Our main products include:

a. Agriculture/Feed chemicals series : Zinc Sulphate, Manganese sulfate etc.),

b. Washing detergent chemicals series : (LABSA, SLES, CEDA,STPP, etc.)

c. Soda alkali chemicals series : ( Caustic Soda , Sodium Sulphate Anhydrous etc.)

d. Water treatment chemical series: (Calcium hypochlorite, TCCA,SDIC, PAC- poly aluminium chloride, PFS, Aluminium sulfate etc.)

e. Adsorbent Desiccant Activated Alumina Ball

f. Raw material Calcium Aluminate ,Aluminium Hydroxide
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Semaglutide 782487-28-9 High Quality and Competitive Price for API Door to door service

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