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Tideglusib 98%+

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CAS No.:

865854-05-3

Content:

98%

Port:

上海

Packaging:

1kg/bag

Price valid (until):

2025-05-01

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Conier Chem&Pharma Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Dicobalt Octacarbonyl,(E,E)-Farnesol,(4S,5R)-4-Methyl-5-phenyloxazolidin-2-one,Geranyl linalool

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Product Description
Seller Information
Inquiry History

Description

4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione Chemical Properties

Melting point	148 - 150oC
Boiling point	511.3±43.0 °C(Predicted)
density	1.393
storage temp.	2-8°C
solubility	DMSO: >15mg/mL
pka	-1.51±0.20(Predicted)
form	powder
color	white to beige
InChI	InChI=1S/C19H14N2O2S/c22-18-20(13-14-7-2-1-3-8-14)19(23)24-21(18)17-12-6-10-15-9-4-5-11-16(15)17/h1-12H,13H2
InChIKey	PMJIHLSCWIDGMD-UHFFFAOYSA-N
SMILES	S1C(=O)N(CC2=CC=CC=C2)C(=O)N1C1=C2C(C=CC=C2)=CC=C1

4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione Usage And Synthesis

Uses	Tideglusib is used in the treatment of brain atrophy, and movement disorder issues.
Uses	Tideglusib has been used: as a reference compound in ADP-GloTM Kinase assay as an allosteric inhibitor of GSK-3β to study its effects on myocardial remodeling and angiogenesis as a differentiation agent (specifically a glycogen synthase kinase (GSK)-3β inhibitor) to convert fibroblast cells into octamer-binding transcription factor-4 (OCT4)+ and vascular endothelial growth factor receptor-2 (VEGFR-2/fetal liver kinase-1 (FLK1)+ cells
Application	Tideglusib is used in the treatment of brain atrophy, and movement disorder issues. As a reagent, Tideglusib has been used: as a reference compound in ADP-GloTM Kinase assay as an allosteric inhibitor of GSK-3β to study its effects on myocardial remodeling and angiogenesis as a differentiation agent (specifically a glycogen synthase kinase (GSK)-3β inhibitor) to convert fibroblast cells into octamer-binding transcription factor-4 (OCT4)+ and vascular endothelial growth factor receptor-2 (VEGFR-2/fetal liver kinase-1 (FLK1)+ cells.

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Items	Specifications

Basic Info

Product Name:

Tideglusib

Other Name:

1,2,4-Thiadiazolidine-3,5-dione,2-(1-naphthalenyl)-4-(phenylmethyl)-;2-(1-Naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione;4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione;Tideglusib;NP 12;NP 031112;945421-01-2;1073650-08-4

CAS No.:

865854-05-3

Molecular Formula:

C19H14N2O2S

InChIKeys:

InChIKey=PMJIHLSCWIDGMD-UHFFFAOYSA-N

Molecular Weight:

334.39166

Exact Mass:

334.39

UNII:

Q747Y6TT42

DSSTox ID:

DTXSID90235682

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

65.9

XLogP3:

4.3

Appearance:

white to beige

Density:

1.4±0.1 g/cm3

Melting Point:

148-150ºC

Boiling Point:

511.3ºC at 760 mmHg

Flash Point:

263.0±28.2 °C

Refractive Index:

1.735

Water Solubility:

Sparingly soluble with water.DMSO: >15mg/mL

Storage Conditions:

2-8°C

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Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Tideglusib Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Dicobalt Octacarbonyl,(E,E)-Farnesol,(4S,5R)-4-Methyl-5-phenyloxazolidin-2-one,Geranyl linalool

Location:
11F ,#20 building, #18 Fuquan Road ,Jiangbei District, CHONGQING 400020, P.R China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
350

Total Annual Revenue:
$10 million-$25 million

Total Employees:
11-50

Year of Establishment:
2010

Inquiry History

9 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	High Purity Tideglusib 99% Powder CAS 865854-05-3 EGC-Tideglusib Powder	1 MT	Oct 31, 2023
United States	Tideglusib	25 G	Jun 13, 2026
Spain	Tideglusib	1 KG	Mar 29, 2025
United Kingdom	Tideglusib	25 G	Jun 8, 2026
United States	Tideglusib	10 G	Apr 25, 2024
United States	Tideglusib	100 MG	Apr 16, 2024
Russia	Tideglusib	0.1 KG	Jan 26, 2025
United States	Tideglusib	100 MG	Apr 17, 2024
Slovenia	Tideglusib	1 KG	Mar 20, 2024

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