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White Powder Vitamin B1 Thiamine Hydrochloride HCl CAS 67-03-8

Name: White Powder Vitamin B1 Thiamine Hydrochloride HCl CAS 67-03-8
Brand: HyperChem
SKU: pr2504101737
Price: 50 USD
Availability: InStock

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CAS No.:

67-03-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

1kg/Bag, 25kg/drum

Price valid (until):

2025-05-10

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Thiamine Hydrochloride
CAS number	67-03-8
EINECS number	259-952-2
Synonym	Thiamine HCl; Vitamin B1; Thiamine hydrochloride; Thio-vitamine; Aneurin; 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol chloride hydrochloride
Description	Thiamine, named as the "thio-vitamine" ("sulfur-containing vitamin"), is a vitamin of the B complex. Thiamine is found in a wide variety of foods at low concentrations. Yeast, yeast extract, and pork are the most highly concentrated sources of thiamine. In general, cereal grains are the most important dietary sources of thiamine, by virtue of their ubiquity. Thiamine hydrochloride (Betaxin) is a (when by itself) white, crystalline hygroscopic food-additive used to add a brothy/meaty flavor to gravies or soups. It is a natural intermediary resulting from a thiamine-HCl reaction, which precedes hydrolysis and phosphorylation, before it is finally employed (in the form of TPP) in a number of enzymatic amino, fatty acid, and carbohydrate reactions.
Structure
Molecular Formula	C12H17N4OS.ClH.Cl
Molecular Weight	397.63 g/mol
Appearance	Solid powder
Quality Standard	USP Standard
Assay	≥98%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Store in cool place. Keep container tightly closed in a dry and well ventilated place.
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Thiamine Hydrochloride More Info

Thiamine hydrochloride, also known as vitamin B1 hydrochloride, is a form of thiamine, an essential vitamin for humans and animals. It plays a crucial role in energy production from carbohydrates and maintaining the health of the nervous and cardiovascular systems.

Mechanism of Action

Thiamine acts as a coenzyme in carbohydrate metabolism, specifically in the decarboxylation of pyruvic acid and α-ketoacids to acetaldehyde and carbon dioxide. It forms thiamine pyrophosphate (TPP), which is crucial for the proper functioning of enzymes like pyruvate dehydrogenase and α-ketoglutarate dehydrogenase. TPP plays a key role in redirecting glycolytic flux, reducing protein glycation, and thus inhibiting endothelial cell proliferation under hyperglycemic conditions

Applications

Thiamine hydrochloride is used to treat or prevent thiamine deficiency, which can occur due to inadequate dietary intake, alcoholism, or certain medical conditions like cirrhosis and gastrointestinal disorders. It is available in oral forms (tablets) and as an injectable solution for severe deficiencies.

Safety and Side Effects

Thiamine is generally safe with minimal side effects when taken orally. However, injectable forms can cause allergic reactions, including anaphylaxis, and other side effects like warmth, sweating, and nausea. Long-term use is usually not problematic, but hypersensitivity reactions can occur with repeated parenteral doses occur.

Routes of Administration

Thiamine hydrochloride can be administered orally in tablet form or as an injectable solution for intramuscular (IM) or slow intravenous (IV) use, especially in severe deficiency cases.

Pharmacokinetics

Absorption: Thiamine is absorbed mainly from the duodenum through both active and passive processes. Absorption following IM administration is rapid and complete.
Protein Binding: Thiamine is about 90-94% bound to proteins.
Metabolism: It is metabolized in the liver.
Half-life and Clearance: Specific data on half-life and clearance are not readily available.
Distribution: Thiamine is distributed in all tissues, with the highest concentrations in the liver, brain, kidneys, and heart.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

Certificates

Basic Info

Product Name:

Thiamine hydrochloride

Other Name:

Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,chloride,hydrochloride (1:1:1);Thiamine,monohydrochloride;Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,chloride,monohydrochloride;3-(4-Amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,β-hydroxyethylthiazolium chloride hydrochloride;Aneurine hydrochloride;Apate drops;Beatine;Bedome;Begiolan;Benerva;Bequin;Berin;Betabion;Betalin S;Betaxin;Bethiazine;Beuion;Bevitine;Bewon;Biuno;Bivatin;Bivita;Clotiamina;Eskapen;Eskaphen;Lixa-Beta;Metabolin;Slowten;THD;Thiadoxine;Thiaminal;Thiamine chloride hydrochloride;Thiamine dichloride;Thiamine hydrochloride;Thiamin hydrochloride;Thiaminium chloride;Thiaminium chloride hydrochloride;Thiamol;Thiavit;Tiamidon;Tiaminal;Trophite;Vetalin S;Vinothiam;Vitamin B1 hydrochloride;Vitaneuron;Thiamine chloride;Thiamin chloride;Thiamin dichloride;Biamine;3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium hydrochloride chloride;63-66-1;70732-86-4;108631-50-1;2173536-98-4;2227489-38-3

CAS No.:

67-03-8

Molecular Formula:

C12H17N4OS.ClH.Cl

InChIKeys:

InChIKey=DPJRMOMPQZCRJU-UHFFFAOYSA-M

Molecular Weight:

337.27

Exact Mass:

336.058

BRN:

3851771

EC Number:

200-641-8

UNII:

M572600E5P

NSC Number:

36226

DSSTox ID:

DTXSID0040622

NCI Thesaurus Code:

C48025

Color/Form:

Crystals from water

HScode:

29362200

Categories:

Vitamins and Minerals Medicines

Characteristics

PSA:

104

XLogP3:

-1.00510

Appearance:

White to almost white Crystalline Powder

Density:

1.3766 (rough estimate)

Melting Point:

248 °C (decomp)

Flash Point:

100ºC

Water Solubility:

H2O: 0.1 g/mL at 20 °C, clear, colorless

Storage Conditions:

2-8°C

Vapor Pressure:

1.8X10-10 mm Hg at 25 deg C (est)

Toxicity:

LD50 in mice (mg/kg): 89.2 i.v.; 8224 orally (Winter)

Odor:

SLIGHT, CHARACTERISTIC

Experimental Properties:

Monoclinic plates in rosette-like clusters. Slight thiazole odor; bitter taste; decomposes at 248 °C. One gram dissolves in approximately 1 mL water, 18 mL glycerol, 100 mL 95% alcohol, 315 mL absolute alcohol; more soluble in methanol. Soluble in propylene glycol. Practically insoluble in ether, benzene, hexane, chloroform. pH of 1% wt/vol solution in water 3.13; pH of 0.1% wt/vol solution in water 3.58. On exposure to air of average humidity, the vitamin absorbs an amount of water corresponding to nearly one mole, forming a hydrate.|HYGROSCOPIC; NUT-LIKE ODOR /HYDROCHLORIDE/|READILY SPLIT BY SULFITE INTO ITS PYRIMIDINE & THIAZOLE CONSTITUENTS|Crystals. MP: 196-200 °C, decomposes; practically nonhygroscopic; pKa = 4.9. Solubility in water (g/100 mL): 2.7 (25 °C); approximately 30 (100 °C). pH of 2% aqueous solution 6.5 to 7.1, more stable than the hydrochloride; suitable for enrichment of flours and feeds, multivitamin preparations /Mononitrate/|SMALL WHITE CRYSTALS OR CRYSTALLINE POWDER /HYDROCHLORIDE/|Thiamine hydrochloride in the dry state is stable. Acidic solutions having a pH below 5.5 preferably from 5.0 to 3.5 are also relatively stable. Alkalies destroy it. It is precipitated from solution by several of the alkaloidal reagents such as mercuric chloride, iodine, picric acid, tannin, and Mayer's reagent. It is sensitive to both oxidizing and reducing agents. /Hydrochloride/|For more Other Experimental Properties (Complete) data for Vitamin B1 (6 total), please visit the HSDB record page.

See More Thiamine hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Thiamine hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

26 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Thiamine HCl	2 MT	Apr 11, 2026
Egypt	Vitamin B1 Thiamine HCL	1500.00 KG	Jan 28, 2026
India	Thiamine HCl	1000 KG	Nov 29, 2025
Turkey	Vitamin B1	1 KG	Apr 16, 2025
Vietnam	Thiamine HCl	75 KG	Apr 10, 2025
India	thamina B1 HCL	1 KG	Jan 2, 2025
Egypt	Vitamin B1 (Hcl Thiamine)	5 KG	Dec 5, 2024
Russia	Thiamine Hydrochloride	500 KG	Aug 8, 2024
Pakistan	Vitamin B1 hydrochloride	50 KG	Apr 8, 2024
Pakistan	VITAMIN B1 HCL	100.00 KG	Mar 18, 2024
Canada	VITAMIN B1	1000 KG	Aug 14, 2023
Philippines	Thiamine Hydrochloride	20 KG	Mar 12, 2024
Moldova	THIAMINE HYDROCHLORIDE	1 KG	Mar 13, 2025
United States	VB1 HCL	1 KG	Sep 9, 2024
Paraguay	Cocamidopropyl Betaine	200.00 KG	Aug 28, 2025
Paraguay	Calcium gluconate usp.anydrous	6000.00 KG	Aug 28, 2025
Paraguay	Analgin-dipyrone metamizol	5000.00 KG	Aug 27, 2025
Paraguay	Dihidroestreptomicin sulfat.steril	2700.00 BOU	Aug 28, 2025
Paraguay	Cobalt gluconte	100.00 KG	Aug 28, 2025
Paraguay	Piperonyl butoxide	100.00 KG	Aug 27, 2025

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White Powder Vitamin B1 Thiamine Hydrochloride HCl CAS 67-03-8

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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