Cetirizine 98% 99%

Cetirizine
Chinese name: Cetirizine
Chinese synonyms: [2-[4-[(4-chlorophenyl) phenylmethyl] -1-piperazinyl] Ethoxy]  ; 2-[2-[4-[(4-chlorophenyl) phenylmethyl] -1-piperazinyl] ethoxy]   Setzan Cetirizine Xiantemin Cetirizine Cetirizine lactose ester Cetirizine 04
English name: Cetirizine
English synonyms:   5-[4-[(4-Chlorophenyl)phenylmethyl]piperazino]-3-oxapentanoicacid; Ceterizine; CetirizineDISCONTINUED(ReplacedwithC1876);  vidix
CAS No. 83881-51-0
Molecular formula: C21H25ClN2O3
Molecular weight: 388.89
EINECS number 251-228-4
Properties of cetirizine
Melting point: 110-115°C
Boiling point: 542.1±45.0°C(Predicted
Density: 1.237±0.06g/cm ³ (Predicted)

The solid acidity coefficient (pKa) of the form is 3.46±0.10(Predicted)
Color: Off-white to light yellow. Water solubility: 101mg/LInChIInChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16- 20 (25) 26 / h1-9, 21 H, 10 to 16 h2, (H, 25, 26) InChIKeyZKLPARSLTMPFCP UHFFFAOYSA - NSMILESC (O) (= O) COCCN1CCN (C (C2 = CC = C (Cl) C = C2) C2 = CC = CC =C2)CC1
CAS Database 83881-51-0
Overview
Cetirizine, a second-generation long-acting H1 antibody antagonist jointly developed by Pfizer of the United States and United Chemicals of Belgium, was first launched in France in 1987. It was approved for marketing by the FDA on December 8, 1995. By 2003, its sales in the global market had exceeded 2 billion US dollars, making it a world-class best-selling drug. It is clinically applicable for the treatment of chronic urticaria, perennial allergic rhinitis, hay fever, itchy conjunctivitis, asthma, etc.
Purpose
Anti-allergic drugs, with long-acting selectivity and strong H1 receptor activity, without sedative side effects. It is used for allergic diseases of the respiratory system, skin and eyes, including chronic idiopathic urticaria, perennial allergic rhinitis, hay fever, mild sedative effect or dry oral mucosa, etc. It is used as an antihistamine

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