Supply High Purity GMP 3-Hydroxytyramine Hydrochloride CAS 62-31-7 3-Hydroxytyramine HCl

Factory Supply High Purity GMP 3-Hydroxytyramine Hydrochloride CAS 62-31-7 3-Hydroxytyramine HCl

What  is 3-Hydroxytyramine Hydrochloride /3-Hydroxytyramine HCl?

Dopamine, a sympathomimetic amine vasopressor, is the naturally occurring immediate precursor of norepinephrine. Dopamine hydrochloride is a white to off-white crystalline powder, which may have a slight odor of hydrochloric acid. It is freely soluble in water and soluble in alcohol. Dopamine HCl is sensitive to alkalies, iron salts, and oxidizing agents. Chemically it is designated as 4-(2-aminoethyl) pyrocatechol hydrochloride, and the structural formula is:

Dopamine Hydrochloride Injection is a clear, practically colorless, sterile, pyrogen-free, aqueous solution of dopamine HCl for intravenous infusion after dilution. Each mL contains either 40 mg, 80 mg, or 160 mg of dopamine hydrochloride (equivalent to 32.3 mg, 64.6 mg and 129.2 mg of dopamine base respectively) in water for injection, q.s. Each mL of all preparations contains the following: sodium metabisulfite 9 mg added as an antioxidant; citric acid, anhydrous 10 mg and sodium citrate, dihydrate 5 mg added as a buffer. The pH range (2.5 to 5.0) may be adjusted with additional citric acid and/or sodium citrate.

Dopamine must be diluted in an appropriate sterile parenteral solution.

Certification 

Technical Date Sheet:

Application:

Dopamine hydrochloride can be used for various types of shock, hypotension. Including toxic shock, cardiogenic shock, hemorrhagic shock, central shock, especially for patients with renal dysfunction Chemicalbook, reduced cardiac output, increased peripheral vascular resistance, and replenalized blood volume. It can also treat cardiac insufficiency and acute renal insufficiency.

Dopamine is the precursor of norepinephrine biosynthesis, as one of the central transmitters, has the effect of excitating β-receptor, A-receptor and dopamine receptor, excitating cardiac β-receptor can increase myocardial contractility and cardiac output. Excitatory dopamine receptors and alpha-receptors cause dilation of kidney, mesentery, coronary artery, and cerebrovascular vessels, and increase Chemicalbook blood flow. It has mild contractile effect on peripheral blood vessels and increases arterial blood pressure. The prominent effect of this drug is to increase renal blood flow and glomerular filtration rate, thus promoting the increase of urine volume and urinary sodium excretion. It is clinically used for various types of shock, especially for shock with reduced systolic force and renal insufficiency.

 



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