Widely used 99% High quality in stock Methylene Blue Trihydrate

Methylene Blue Trihydrate More Info

Methylene Blue Trihydrate, first synthesized as a zinc chloride salt in 1876, is a heterocyclic aromatic compound with the chemical formula C₁₆H₁₈ClN₃S. It appears as a dark green crystalline powder that dissolves in water to form a deep blue solution. Its unique redox properties allow it to act as both an oxidizing and reducing agent, making it valuable in medical and industrial applications. Historically, it gained prominence as a biological stain and an antidote for poisoning before expanding into broader therapeutic uses.

Medical Applications and Pharmacological Effects

Methylene blue has been widely used in medicine for:

Treating methemoglobinemia (caused by nitrites, chlorates, quinones, aniline, or nitrobenzene) at low doses.

Counteracting cyanide poisoning at high concentrations.

Combining with local anesthetics for pain relief.

Industrial and Commercial Uses

Methylene blue serves multiple roles across industries:

Textile & Paper Dyeing: Used for coloring cotton, silk, paper, and wood, as well as in ink production.

Biological Staining: Acts as a bacterial stain and redox indicator in laboratories.

Aquaculture: Functions as an antifungal and antiparasitic agent to treat fish diseases (e.g., ichthyophthiriasis, saprolegniosis) and reduce transport mortality.

Cosmetics: Emerging as an anti-aging ingredient by stimulating collagen synthesis and neutralizing free radicals.

Handling and Synthesis

Operational Considerations

Recommended Storage: Keep in airtight, light-resistant containers to maintain stability.

Environmental Impact: Proper disposal methods should be followed to minimize ecological effects.

Synthesis Process

Methylene blue is produced via oxidative condensation of N,N-dimethyl-p-phenylenediamine with thiosulfate, followed by oxidation with sodium dichromate and manganese dioxide. The process involves:

Acidic reaction with zinc chloride and sodium thiosulfate.

Oxidation at 70–85°C, then purification via crystallization.

Final yield (~27.4%) after recrystallization with hydrochloric acid.

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.