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Home > Pharmaceutical Intermediates > Antispasticity Agents > Cidofovir for Sale > 99% Cidofovir Veterinary Antiviral
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99% Cidofovir Veterinary Antiviral

1 Inquiries

Unit Price: Get Latest Price
CAS No.:

113852-37-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

1kg/Bag, 25kg/drum

Price valid (until):

2025-10-19

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Name

    Cidofovir

    CAS number

    113852-37-2

    Description

    Cidofovir is a synthetic nucleotide analog of cytosine monophosphate, specifically designed as an antiviral agent through rational drug design.

    Structural formula

     Shop 99% Cidofovir Veterinary Antiviral-Detailed Image 1

    Molecular Formula

    C8H14N3O6P

    Molecular Weight

    279.19 g/mol

    Appearance

    White powder

    Quality Standard

    99%

    Storage Condition

    Cool dry place( away from the light)

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China

    Cidofovir More Info

    Cidofovir is a synthetic nucleotide analog of cytosine monophosphate, specifically designed as an antiviral agent through rational drug design. Its development was driven by the need to treat severe viral infections caused by double-stranded DNA viruses, particularly those affecting immunocompromised patients. Unlike many antiviral agents that require viral-encoded kinases for activation, cidofovir is selectively phosphorylated by cellular enzymes to its active diphosphate form. This active metabolite then acts as a competitive inhibitor and alternative substrate for viral DNA polymerase, incorporating into the growing DNA chain and causing premature chain termination. This mechanism allows it to bypass viral resistance mechanisms that often target virus-specific activation pathways, giving it a broad spectrum of activity against various DNA viruses.

     

    Uses and Applications

    The primary application of cidofovir is in the treatment of severe viral infections in immunocompromised patients, particularly those with HIV/AIDS or undergoing organ transplantation. It is specifically indicated for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS when other therapies are unsuitable or ineffective. Beyond this approved indication, it is used off-label as a salvage therapy for other difficult-to-treat DNA viral infections, including adenovirus, BK virus nephropathy in transplant recipients, progressive multifocal leukoencephalopathy (PML), and refractory herpesvirus infections. Due to its poor oral bioavailability, it is administered exclusively as an intravenous infusion, typically in a healthcare setting with appropriate monitoring and supportive care.

     

    Application Market

    The market for cidofovir is a highly specialized and niche segment within the antiviral pharmaceutical market. Its use is restricted to hospital settings and specialized infectious disease clinics that manage complex immunocompromised patients. The market is limited due to its specific indication, significant toxicity profile, and the availability of alternative antiviral agents for many conditions. It is considered a second-line or salvage therapy, which keeps its volume relatively low but essential for specific patient populations. Distribution is tightly controlled through hospital pharmacies and specialty pharmaceutical suppliers rather than retail channels. It is available as a branded product and may also be supplied by specialized compounding pharmacies or generic manufacturers in some markets.

     

    Important Considerations

    Cidofovir is a potent nephrotoxic agent that requires extreme caution in administration and monitoring. Its use is contraindicated in patients with pre-existing renal impairment and those receiving other nephrotoxic drugs. Administration must be preceded by intravenous hydration with normal saline and concomitant oral probenecid to reduce the risk of kidney damage. Other serious adverse effects include neutropenia and ocular hypotony. In an industrial or laboratory setting, handling the pure active pharmaceutical ingredient requires stringent containment procedures and personal protective equipment (PPE) to prevent any occupational exposure through inhalation or skin contact, as it is a potent antimetabolite. It is for use only in finished, sterile, injectable dosage forms administered under strict medical supervision in settings equipped to manage potential serious adverse reactions.


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    FAQ

    Q1. Can I get a free sample?

    We can send you a samll free sample, and you only need to pay for the shipping cost.


    Q2. What is the HyperChem payment term?

    T/T in advance
    LC at sight
    DP at sight

    Bank transfer

    PayPal

    Bitcoin...


    Q3. What is HyperChem shipment policy?

    Our policy is to strive for the quickest shipment time possible.

    For ready stock samples, they are usually shipped within 3 working days after payment received.
    For non-ready stock, please contact HyperChem sales team to negotiate.


    Q4. What is HyperChem shipment term?

    By Express  
    FedEx  UPS  DHL  EMS                               
    Fast: 3-7 days around, high cost, door to door service

    By Air                                        
    Suitable for more than 50kg 
    Fast: 3-7 days, hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Fast: 7-45 days, low cost, port to port, professional broker needed 


    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.


    Q5. What HyperChem will provide after shipment?

    For sample orders: 
    After shipment is done, an timely email including:

    1. Track details (Fedex /TNT/DHL/EMS Track number)
    2. Packaging photo
    3. COA, MSDS, etc
    4. Dispatch date & Estimated arriving time
    5. Shipping invoice

    For commercial orders
    A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.



    Company Profile

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.


    Among them, our key client industrial sectors around the global are:

    Pharmaceuticals
    Nutrition Ingredients/ Dietary supplements
    Cosmetic Ingredients
    Food Ingredients
    Veterinary API
    Agriculture fertilizer
    Custom Synthesis lab supply


    HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.




    ECHEMI Editorial Reference
    Cidofovir launched as a first-line treatment for CMV retinitis in AIDS patients. It is a nucleotide analog with potent activity against a broad spectrum of DNA viruses, e.g., HSVl, HSV2, CMV, adenovirus and papillomavirus. Cidofovir can be synthesized by a number of methods, the most efficient involves ring openning of (R)-glycidol with cytosine. Metabolically, cidofovir does not require intracellular activation by virally-encoded enzymes like similar compounds, e.g., aciclovir or gancicl
    Solid
    Cidofovir anhydrous is cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients. It has a role as an antiviral drug, an antineoplastic agent, an anti-HIV agent and a photosensitizing agent. It is a pyrimidone and a member of phosphonic acids. It is a conjugate acid of a cidofovir(2-) and a cidofovir(1-).|Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis. It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.|Cidofovir anhydrous is a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of cidofovir anhydrous is as a DNA Polymerase Inhibitor.|Cidofovir is a nucleoside analogue and antiviral agent which is used in therapy of serious cytomegalovirus infections in immunocompromised patients. Cidofovir has been associated with mild-to-moderate serum aminotransferase elevations during intravenous therapy, but has not been convincingly linked to cases of clinically apparent acute liver injury.|Cidofovir Anhydrous is an anhydrous form of cidofovir, a synthetic, acyclic monophosphate nucleotide analog of deoxycytidine with antiviral activity, mostly used against cytomegalovirus (CMV). After incorporation into the host cell, cidofovir is phosphorylated by pyruvate kinases to its active metabolite cidofovir diphosphate. Cidofovir diphosphate, bearing structural similarity to nucleotides, competes with deoxycytosine-5-triphosphate (dCTP) for viral DNA polymerase and gets incorporated into the growing viral DNA strands. As a result, it prevents further DNA polymerization and disrupts DNA replication of viruses.|An acyclic nucleoside phosphonate that acts as a competitive inhibitor of viral DNA polymerases. It is used in the treatment of RETINITIS caused by CYTOMEGALOVIRUS INFECTIONS and may also be useful for treating HERPESVIRUS INFECTIONS.

    Basic Info
    Product Name:

    Cidofovir

    Other Name:

    Phosphonic acid,P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-;Phosphonic acid,[[2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-,(S)-;Phosphonic acid,[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-;P-[[(1S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid;(S)-HPMPC;HPMPC;1-(S)-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine;1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine;(S)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine;GS 0504;Cidofovir;Vistide;Cidovir;Cidofovir monophosphate

    CAS No.:

    113852-37-2

    Molecular Formula:

    C8H14N3O6P

    InChIKeys:

    InChIKey=VWFCHDSQECPREK-LURJTMIESA-N

    Molecular Weight:

    279.19

    Exact Mass:

    279.19

    EC Number:

    1308068-626-2

    UNII:

    768M1V522C

    NSC Number:

    742135

    DSSTox ID:

    DTXSID3043734

    NCI Thesaurus Code:

    C77925

    Color/Form:

    Fluffy white powder|White crystalline powder

    ATC Code:

    J05AB12|J - Antiinfectives for systemic use

    HScode:

    2933599090

    Categories:

    Antispasticity Agents

    Characteristics
    PSA:

    146

    XLogP3:

    -3.9

    Appearance:

    Solid

    Density:

    1.76±0.1 g/cm3(Predicted)

    Melting Point:

    260 °C (decomp)

    Boiling Point:

    609.5ºC at 760 mmHg

    Flash Point:

    322.4±34.3 °C

    Refractive Index:

    1.656

    Water Solubility:

    deionized water: ≥5mg/mL (warmed)

    Storage Conditions:

    room temp

    Vapor Pressure:

    2.11E-17mmHg at 25°C

    Specific rotation:

    D20 -97.3° (c = 0.80 in water)

    Experimental Properties:

    UV maximum (pH 2): 279 nm (E 13,000) /Monohydrate/

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Germ cell mutagenicity, Category 2

    Carcinogenicity, Category 2

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H341 Suspected of causing genetic defects

    H351 Suspected of causing cancer

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Russia

    Cidofovir

    10 G Sep 19, 2025
    Post an enquiry for this product
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