99% Cidofovir Veterinary Antiviral
1 Inquiries
113852-37-2
Pharmaceutical Grade
99%
SHANGHAI
HyperChem
1kg/Bag, 25kg/drum
2025-10-19
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceCidofovir launched as a first-line treatment for CMV retinitis in AIDS patients. It is a nucleotide analog with potent activity against a broad spectrum of DNA viruses, e.g., HSVl, HSV2, CMV, adenovirus and papillomavirus. Cidofovir can be synthesized by a number of methods, the most efficient involves ring openning of (R)-glycidol with cytosine. Metabolically, cidofovir does not require intracellular activation by virally-encoded enzymes like similar compounds, e.g., aciclovir or gancicl
Solid
Cidofovir anhydrous is cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients. It has a role as an antiviral drug, an antineoplastic agent, an anti-HIV agent and a photosensitizing agent. It is a pyrimidone and a member of phosphonic acids. It is a conjugate acid of a cidofovir(2-) and a cidofovir(1-).|Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis. It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.|Cidofovir anhydrous is a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of cidofovir anhydrous is as a DNA Polymerase Inhibitor.|Cidofovir is a nucleoside analogue and antiviral agent which is used in therapy of serious cytomegalovirus infections in immunocompromised patients. Cidofovir has been associated with mild-to-moderate serum aminotransferase elevations during intravenous therapy, but has not been convincingly linked to cases of clinically apparent acute liver injury.|Cidofovir Anhydrous is an anhydrous form of cidofovir, a synthetic, acyclic monophosphate nucleotide analog of deoxycytidine with antiviral activity, mostly used against cytomegalovirus (CMV). After incorporation into the host cell, cidofovir is phosphorylated by pyruvate kinases to its active metabolite cidofovir diphosphate. Cidofovir diphosphate, bearing structural similarity to nucleotides, competes with deoxycytosine-5-triphosphate (dCTP) for viral DNA polymerase and gets incorporated into the growing viral DNA strands. As a result, it prevents further DNA polymerization and disrupts DNA replication of viruses.|An acyclic nucleoside phosphonate that acts as a competitive inhibitor of viral DNA polymerases. It is used in the treatment of RETINITIS caused by CYTOMEGALOVIRUS INFECTIONS and may also be useful for treating HERPESVIRUS INFECTIONS.Basic Info-
Product Name:
Cidofovir
Other Name:Phosphonic acid,P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-;Phosphonic acid,[[2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-,(S)-;Phosphonic acid,[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-;P-[[(1S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid;(S)-HPMPC;HPMPC;1-(S)-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine;1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine;(S)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine;GS 0504;Cidofovir;Vistide;Cidovir;Cidofovir monophosphate
CAS No.:113852-37-2
Molecular Formula:C8H14N3O6P
InChIKeys:InChIKey=VWFCHDSQECPREK-LURJTMIESA-N
Molecular Weight:279.19
Exact Mass:279.19
EC Number:1308068-626-2
UNII:768M1V522C
NSC Number:742135
DSSTox ID:DTXSID3043734
NCI Thesaurus Code:C77925
Color/Form:Fluffy white powder|White crystalline powder
ATC Code:J05AB12|J - Antiinfectives for systemic use
HScode:2933599090
Categories:
Characteristics-
PSA:
146
XLogP3:-3.9
Appearance:Solid
Density:1.76±0.1 g/cm3(Predicted)
Melting Point:260 °C (decomp)
Boiling Point:609.5ºC at 760 mmHg
Flash Point:322.4±34.3 °C
Refractive Index:1.656
Water Solubility:deionized water: ≥5mg/mL (warmed)
Storage Conditions:room temp
Vapor Pressure:2.11E-17mmHg at 25°C
Specific rotation:D20 -97.3° (c = 0.80 in water)
Experimental Properties:UV maximum (pH 2): 279 nm (E 13,000) /Monohydrate/
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Germ cell mutagenicity, Category 2
Carcinogenicity, Category 2
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H341 Suspected of causing genetic defects
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements
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Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
10
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2013
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Certifications:
Certification Report by Bureau Veritas
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
Russia
Cidofovir
10 G Sep 19, 2025 Post an enquiry for this product