Top Quality Veterinary Raw Material Florfenicol CAS 73231-34-2 with good price and fast delivery

Florfenicol More Info

Florfenicol is a synthetic broad-spectrum antibiotic belonging to the amphenicol class, specifically developed for veterinary use. It is a fluorinated analog of thiamphenicol, which itself is a derivative of chloramphenicol. The key structural modification — the replacement of a hydroxyl group with a fluorine atom—was strategically designed to enhance antibacterial activity and overcome specific bacterial resistance mechanisms, particularly those involving acetylation. This alteration also eliminates the association with dose-dependent, irreversible bone marrow suppression (aplastic anemia) that led to the severe restrictions on chloramphenicol use in food-producing animals. Its primary mechanism of action is the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit.

Uses and Applications

The primary application of Florfenicol is in the treatment of bacterial infections in food-producing and companion animals. It is highly effective against a range of Gram-negative and Gram-positive pathogens. Key uses include the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. In aquaculture, it is a critical medication for controlling enteric septicemia in catfish caused by Edwardsiella ictaluri and various bacterial diseases in other farmed fish and shrimp. It is also used in swine for respiratory disease and in poultry. The drug is formulated for oral administration (in feed or water), as an injectable solution, and as medicated baths for fish.

Application Market

The market for Florfenicol is substantial and global, firmly positioned within the veterinary antimicrobial sector. Demand is heavily driven by the intensive livestock industries (cattle and swine) and the rapidly expanding aquaculture industry, particularly in Asia and the Americas. It is available as a generic product from multiple manufacturers, but its use is often regulated as a prescription-only veterinary medicine (POM-V) to promote responsible use. The market is characterized by a variety of branded and generic formulations, including combination products with anti-inflammatory drugs like flunixin. Its importance in food animal production ensures a consistent and significant market presence.

Important Considerations

The use of Florfenicol must be strictly in accordance with label directions and under veterinary supervision to ensure both efficacy and food safety. Adherence to prescribed withdrawal periods is mandatory before milk or meat from treated animals can enter the food chain. Although the risk of irreversible bone marrow toxicity is significantly lower than with chloramphenicol, reversible dose-related bone marrow suppression can occur. Its use is contraindicated in animals with known hypersensitivity to amphenicols. Prudent use principles should be followed to minimize the development of antimicrobial resistance. In aquaculture, environmental considerations regarding the release of medicated feed into water systems are important. Individuals handling the product should use standard precautions to avoid skin contact or inhalation of dust.

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FAQ

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We can send you a samll free sample, and you only need to pay for the shipping cost.

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For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

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Suitable for more than 50kg 
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3. COA, MSDS, etc
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For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.