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Ropinirole Hydrochloride API - A Dopamine Agonist for Parkinson's Disease Treatment.

Name: Ropinirole Hydrochloride API - A Dopamine Agonist for Parkinson's Disease Treatment.
Brand: Tianrui
SKU: pr2511121365
Price: 11 USD
Availability: InStock

Unit Price: Get Latest Price 

CAS No.:

91374-20-8

Grade:

Pharmaceutical Grade

Content:

101%

Port:

Qingdao

Brand:

Tianrui

Packaging:

Sealed fiber drum

Price valid (until):

2025-11-12

Contact Supplier

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Hefei Tianrui Pharmaceutical Chemical Co., Ltd.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

APIs

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Product Description
Seller Information

Description

About Product

Ropinirole Hydrochloride (CAS: 91374-21-9) is a high-purity active pharmaceutical ingredient (API) that functions as a non-ergot dopamine agonist. Specifically developed for the treatment of Parkinson's disease and restless legs syndrome, it demonstrates excellent efficacy in managing neurological symptoms. Manufactured by Hefei TianRui Pharmaceutical under strict cGMP conditions, our Ropinirole Hydrochloride API guarantees high purity, low impurity profiles, and reliable quality for central nervous system drug formulations.

Items	Specifications
Product Name	Ropinirole Hydrochloride
CAS Registry Number	91374-21-9
IUPAC Name	4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride
Molecular Weight	296.84 g/mol
Solubility	It is soluble in water, soluble in methanol, and slightly soluble in ethanol.
Melting Point	243-250°C
Primary Use	Treatment of Parkinson's disease Treatment for restless legs syndrome

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Company Profile

Founded: 2014
Focus: High-tech enterprise specializing in the development and industrialization of small-molecule pharmaceutical synthesis technology
Facilities:
- Two workshops (TR1 & TR2) with total capacity ≈ 1000 tons/year
- Reactors: 3000L×15, 2000L×10, and numerous smaller reactors (1000L, 500L, 100L)
- Ultra-low temperature cryogenic reactor (explosion-proof workshop included)
- GMP workshop & clean room
QC Lab Equipment: GC×2, HPLC×3, UV, IR, KF titrator, etc.

About company

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In 2015, the company developed polypeptide absorbent permeation enhancers: ethyl 8-bromo-octanoate and Carsalam, which is the 1st and only qualified Chinese supplier of Semaglutide to meet the internal control requirements of innovator Novo Nordisk.

In 2020, the company independently developed and optimized 8-bromo-octanoic acid and 6-bromo-caproic acid to become a COVID-19 vaccine carrier manufacturer and supplier to Moderna company, contributing its share to the fight against COVID-19.

In 2022, Tianrui R&D Center and cGMP manufacturing facility was inaugurated and put into operation. And in the same year, polypeptide absorbent permeation enhancers SNAC (Salcaprozate Sodium) has successfully obtained the domestic CDE registration number (F20220000072) and the US FDA registration number (037135), and another batch of innovative APIs and pharmaceutical excipients are under registration and approval.

Basic Info

Product Name:

Ropinirole hydrochloride

Other Name:

2H-Indol-2-one,4-[2-(dipropylamino)ethyl]-1,3-dihydro-,hydrochloride (1:1);2H-Indol-2-one,4-[2-(dipropylamino)ethyl]-1,3-dihydro-,monohydrochloride;SKF 101468 hydrochloride;Ropinirole hydrochloride;SKF 101468A;Requip;Parkirop;Ropitar;Ropark;Repreve;Ronirol;Adartrel;Spiroco XL;Ralnea XL;Clevor;115616-44-9

CAS No.:

91374-20-8

Molecular Formula:

C16H24N2O.ClH

InChIKeys:

InChIKey=XDXHAEQXIBQUEZ-UHFFFAOYSA-N

Molecular Weight:

296.84

Exact Mass:

296.165527

EC Number:

1308068-626-2

UNII:

D7ZD41RZI9

DSSTox ID:

DTXSID50238533

NCI Thesaurus Code:

C47710

ATC Code:

QN04BC04

HScode:

2933790090

Categories:

CNS Agents

Characteristics

PSA:

32.3

XLogP3:

3.78570

Appearance:

light yellow

Melting Point:

241-243 °C

Boiling Point:

410.5°C at 760 mmHg

Water Solubility:

H2O: >10mg/mL

Storage Conditions:

room temp

See More Ropinirole hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H400 Very toxic to aquatic life
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Ropinirole hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
APIs

Location:
No.23,lntersection of Fenglehe Avenue and Leiyang Road, Huagang Town,Feixi County, Hefei, Anhui, China.

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$50 million-$100 million

Total Employees:
11-50

Year of Establishment:
2014

About TianRui

Hefei TianRui Pharmaceutical Chemical Co., Ltd was founded in 2014 as a high-tech enterprise focused on the development and industrialization of pharmaceutical small molecule synthesis technology. Our workshop and R&D center are located in Hefei HuaGang Provincial Industrial Park, Anhui Province. We are committed to providing professional technical services and commercialization of small molecule specialty APIs, CGMP standard intermediates, and functional pharmaceutical excipients and MRNA vaccine vectors for domestic and overseas well-known pharmaceutical companies.

Main Events

In 2015, the company developed polypeptide absorbent permeation enhancers: ethyl 8-bromo-octanoate and Carsalam, which is the 1st and only qualified Chinese supplier of Semaglutide to meet the internal control requirements of innovator Novo Nordisk.

In 2020, the company independently developed and optimized 8-bromo-octanoic acid and 6-bromo-caproic acid to become a COVID-19 vaccine carrier manufacturer and supplier to Moderna company, contributing its share to the fight against COVID-19.

In 2022, Tianrui R&D Center and cGMP manufacturing facility was inaugurated and put into operation. And in the same year, polypeptide absorbent permeation enhancers SNAC (Salcaprozate Sodium) has successfully obtained the domestic CDE registration number (F20220000072) and the US FDA registration number (037135), and another batch of innovative APIs and pharmaceutical excipients are under registration and approval.
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