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raw material Ergothioneine

Name: raw material Ergothioneine
Brand: Hyper Chem
SKU: pr2511271744
Price: 5000 USD
Availability: InStock

9 Inquiries

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CAS No.:

497-30-3

Grade:

Cosmetics Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Sample Available:

Yes

Price valid (until):

2025-12-27

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Details
Seller Information
Inquiry History

Description

Name	L-(+)-Ergothioneine
CAS number	497-30-3
Description	Ergothioneine is a naturally occurring thiol/thione derivative of histidine, synthesized by certain fungi and bacteria and acquired by humans through dietary sources like mushrooms. It functions as a potent antioxidant and cytoprotectant, accumulating in tissues exposed to oxidative stress via the highly specific transporter OCTN1 (SLC22A4). Ergothioneine has been implicated in cellular protection against oxidative damage, inflammation, and mitochondrial dysfunction, with growing interest in its potential roles in aging and chronic disease mitigation
Synonym	Ergothioneine; L-Ergothioneine; L-(+)-Ergothioneine; 2-Mercaotohistidine Betaine; Sympectothion; NSC 7175; NSC-7175; NSC7175
Appearance	Solid powder
Quality Standard	USP, EP, BP, CP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Ergothioneine More Info

Ergothioneine (ET) is a naturally occurring thiol amino acid with unique antioxidant and cytoprotective properties, widely used in pharmaceuticals, cosmetics, and functional foods.

Ergothioneine: Product Overview

Ergothioneine (CAS No.: 497-30-3; Molecular Formula: C9H15N3O2S; Molecular Weight: 229.30) is a stable, water-soluble antioxidant naturally synthesized by fungi (e.g., Aspergillus, Penicillium) and certain bacteria. Unlike most antioxidants, it accumulates specifically in human tissues (liver, kidneys, red blood cells) via the OCTN1 transporter, offering long-lasting protection against oxidative stress, inflammation, and cellular damage.

Core Applications

Pharmaceuticals: Used in formulations for neuroprotection (e.g., Alzheimer’s disease research), cardiovascular health, and reducing side effects of chemotherapy/radiation.

Cosmetics: Added to anti-aging skincare (serums, creams) to neutralize free radicals, prevent collagen degradation, and improve skin barrier function.

Functional Foods & Beverages: Incorporated into health supplements, energy drinks, and fortified foods to enhance antioxidant capacity and support immune function.

Key Advantages for Trade

High Stability: Resists heat, pH fluctuations, and oxidation (superior to glutathione in harsh processing conditions).

Safety Profile: GRAS (Generally Recognized as Safe) certified by the FDA; non-toxic, non-irritating, and compatible with most formulations.

Scalable Supply: Available via microbial fermentation (industrial-grade purity: ≥98%) and natural extraction (for premium food/cosmetic grades).

Technical Specifications (Typical)

Purity: ≥98% (HPLC)

Appearance: White crystalline powder

Solubility: Soluble in water (≥50 g/L at 25 ℃ ), slightly soluble in ethanol

Storage: Store in a cool, dry place (2-8 ℃ ) in sealed containers; shelf life ≥2 years.

ECHEMI Editorial Reference

Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant[1].

Basic Info

Product Name:

Ergothioneine

Other Name:

1H-Imidazole-4-ethanaminium,α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-,inner salt,(αS)-;1H-Imidazole-4-ethanaminium,α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-,hydroxide,inner salt,(S)-;Ammonium,[1-carboxy-2-(2-mercaptoimidazol-4-yl)ethyl]trimethyl-,hydroxide,inner salt,L-(+)-;Ergothioneine;Sympectothion;Thiasine;Thioneine;Histidine,2-mercapto-,trimethylbetaine;Histidine,2-mercapto-N,N-dimethyl-,betaine;L-Ergothioneine;2-Mercapto-N,N-dimethylhistidine methyl ester betaine;2-Mercaptohistidine trimethylbetaine;Ergothionine;1H-Imidazole-4-ethanaminium,α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-,inner salt,(S)-;2-Mercaptohistidine betaine;NSC 7175;Thiotane;thiotaine;Phytothioneine;(S)-5-(2-Carboxy-2-(trimethylammonio)ethyl)-1H-imidazole-2-thiolate;(2S)-3-(2-Sulfanyl-1H-imidazol-4-yl)-2-(trimethylazaniumyl)propanoate;616-50-2;644-57-5;6330-63-8

CAS No.:

497-30-3

Molecular Formula:

C9H15N3O2S

InChIKeys:

InChIKey=SSISHJJTAXXQAX-ZETCQYMHSA-N

Molecular Weight:

229.3

Exact Mass:

229.088501

EC Number:

207-843-5

Categories:

Antioxidant Ingredient

Characteristics

PSA:

96.3

XLogP3:

0.3

Appearance:

Solid

Density:

1.2541 (rough estimate)

Melting Point:

280 °C (decomp)

Storage Conditions:

-20ºC

See More Ergothioneine Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Ergothioneine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- Certification Report by Bureau Veritas
About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

9 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	ergothioneine	1 G	Jul 23, 2026
Austria	Ergothioneine 99% White powder	10 G	Jun 29, 2026
United States	L-Ergothioneine	1 KG	Jul 4, 2025
Singapore	Ergothioneine 99% white powder	10 MG	Mar 18, 2024
India	Ergothioneine 99% white powder	0.025 G	Jan 18, 2024
Denmark	ergothioneine	1 MT	Dec 2, 2024
Greece	Ergothioneine	1 KG	Apr 12, 2024
India	Ergothioneine	1 KG	Mar 12, 2024
India	Ergothioneine	25 KG	Nov 4, 2024

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raw material Ergothioneine

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