99% Cosmetic Grade Tranexamic Acid CAS 1197-18-8 White Raw Power With Best Price

Tranexamic acid More Info

Tranexamic acid is a synthetic derivative of the amino acid lysine, classified as an antifibrinolytic agent with the CAS Registry Number 1197-18-8. Its molecular structure is characterized by a cyclohexane ring replacing the terminal amino group of the lysine side chain, a critical modification that allows it to bind with high affinity to the lysine-binding sites on plasminogen. This specific structural mimicry underlies its highly selective and reversible mechanism as a competitive inhibitor, designed to mimic a key biological interaction.

The primary mechanism of action for this compound is the competitive and reversible inhibition of the activation of plasminogen to plasmin, and the direct inhibition of plasmin's proteolytic activity. By occupying the binding sites on plasminogen that are necessary for its attachment to fibrin, tranexamic acid prevents the premature breakdown of fibrin clots. This antifibrinolytic effect stabilizes existing blood clots at sites of vascular injury, thereby promoting hemostasis not by inducing new thrombosis, but by protecting the body's natural physiological clot from being dissolved too quickly.

The clinical applications of tranexamic acid are broad and critically important across multiple medical specialties. Its primary use is to control or prevent excessive bleeding resulting from hyperfibrinolysis in scenarios such as major trauma, postpartum hemorrhage, and during surgical procedures like cardiac surgery and orthopedic joint replacements. It is also effectively used in the management of heavy menstrual bleeding and as a prophylactic agent in patients with hemophilia undergoing dental or minor surgical procedures. Furthermore, it serves as a first-line treatment for acute attacks of hereditary angioedema.

This pharmaceutical is available in various formulations to suit different clinical needs. It can be administered intravenously for rapid action in emergencies, orally for long-term or preventive treatment, or applied topically in solutions for mucosal bleeding. Its pharmacokinetics show good bioavailability after oral administration and rapid distribution, with most of the drug being excreted unchanged in the urine. This necessitates dosage adjustment in patients with significant renal impairment to avoid accumulation and potential side effects.

The safety profile of tranexamic acid is generally favorable when used appropriately for its approved indications. Common side effects are usually mild and can include gastrointestinal discomfort with oral use. The most serious risk, though rare, is the potential for thrombotic events, such as deep vein thrombosis or pulmonary embolism, particularly if used in patients with a pre-existing thrombotic tendency or active thromboembolic disease. Its contraindications include a history of venous or arterial thrombosis and significant renal failure. When administered correctly, it is a remarkably cost-effective and life-saving medication in global health.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.