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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Methylparaben for Sale > China Professional Manufactory Supply High-Quality MEthyI p-hydroxybenzoate(CAS 99-76-3)
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China Professional Manufactory Supply High-Quality MEthyI p-hydroxybenzoate(CAS 99-76-3)

9 Inquiries

Unit Price: Get Latest Price
CAS No.:

99-76-3

Content:

99%

Port:

Yancheng

Brand:

Jiuquan Zhihe

Packaging:

25kg/barrel(350X450)4bags/eardboard drum

Price valid (until):

2025-12-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

4-Methoxybenzoic acid,p-Anisoyl chloride,4-Hydroxybenzoic acid,4-Hydroxybenzonitrile,MEthyI p-hydroxybenzoate,EthyI p-hydroxybenzoate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Our Reference Specification, for more details, pls contact us for COA,MSDS and certification:

    Mobile:+86-18061767636;Whatsapp: +8618061767636;Mail: liuziyao@jsrdhb.com.cn

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    ECHEMI Editorial Reference
    Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity[1].
    Methylparaben occurs as colorless crystals or a white crystalline powder. It is odorless or almost odorless and has a slight burning taste. Soluble in alcohol,ether; slightly soluble in water, benzene, and carbontetrachloride.
    ChEBI: Methylparaben is a 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries. It has a role as a plant metabolite, an antimicrobial food preservative, a neuroprotective agent and an antifungal agent.
    The carcinogenic potential of methyl paraben has been studied in rodents. Several studies are available, but none that expose animals via oral or dermal routes. No evidence of a carcinogenic effect was observed following intravenous or subcutaneous injection .
    Fractionally crystallise the ester from its melt, and recrystallise it from *benzene, then from *benzene/MeOH and dry it over CaCl2 in a vacuum desiccator. [Beilstein 10 IV 360.]

    Basic Info
    Product Name:

    Methylparaben

    Other Name:

    NIPAGIN PLAIN;P-HYDROXYBENZOIC ACID METHYL ESTER;RARECHEM AL BF 0098;METHYLPARABEN,FCC;METHYLPARABEN,NF;4-HYDROXYBENZOICACIDMETHYLESTER(METHYLPARABEN);4-HYDROXYLMETHYLBENZOATE;Methyl-4-hydroxybenzoat

    CAS No.:

    99-76-3

    Molecular Formula:

    C8H8O3

    InChIKeys:

    LXCFILQKKLGQFO-UHFFFAOYSA-N

    Molecular Weight:

    152.15

    Exact Mass:

    152.15

    BRN:

    509801

    EC Number:

    202-785-7

    TSCA:

    TSCA listed

    Color/Form:

    White to almost white

    HScode:

    29182930

    Characteristics
    PSA:

    46.5

    XLogP3:

    2

    Appearance:

    White to almost white Crystalline Powder

    Density:

    1,46g/cm

    Melting Point:

    125-128 °C (lit.)

    Boiling Point:

    298.6 °C

    Flash Point:

    280°C

    Refractive Index:

    1.4447 (estimate)

    Water Solubility:

    Slightly soluble in water.

    Storage Conditions:

    0-6°C

    Vapor Pressure:

    0.000005 hPa (20 °C)

    Toxicity:

    ADI 0~10mg/kg(FAO/WHO,2001).GRAS(FDA,§184.1490,2000).LD503000mg/kg(Dog, mouth)

    Flammability characteristics:

    Flammable, spicy and irritating smoke emitted from the fire

    Odor:

    odorless or faint char. odor, sl. burning taste

    PH:

    5.8 (H2O, 20°C) (saturated solution)

    PKA:

    pKa 8.15(H2O,t =20.0) (Uncertain)

    Henrys Law Constant:

    4.5×103mol/(m3Pa) at 25℃, HSDB (2015)

    Autoignition Temperature:

    >600 °C

    Critical Temperature & Pressure:

    room temp

    Hazard Identification

    Classification of the substance or mixture

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    No signal word

    Hazard statement(s)

    H411 Toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P273 Avoid release to the environment.

    Response

    P391 Collect spillage.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Keep container tightly closed in a dry and well-ventilated place.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    4-Methoxybenzoic acid,p-Anisoyl chloride,4-Hydroxybenzoic acid,4-Hydroxybenzonitrile,MEthyI p-hydroxybenzoate,EthyI p-hydroxybenzoate

    Location:

    Room 201, Build Zonghe,Dongzhen Jiancai Industrial Park, Yumen, Jiuquan, Gansu, CN

    Total Annual Revenue:

    $25 million-$50 million

    Total Employees:

    101-200

    Year of Establishment:

    2020

    Company Certificates
    • Jiuquan Zhihe New Material Co., Ltd.ISO 9001 ISO 9001
    • Jiuquan Zhihe New Material Co., Ltd.ISO 14001 ISO 14001

    Jiuquan Zhihe New Material Co. , Ltd., located in the Yumen c hemical i ndustrial p ark in Jiuquan City, is a high-tech enterprise specializing in the research and development, production, manufacturing, and sales of fine chemical products such as pharmaceutical intermediates, food additives, and custom chemicals.


    Since its establishment in 2000, the company has undergone multiple rounds of government-led industrial upgrading and self-driven technological and equipment enhancements. It has now grown into a professional production enterprise with an annual capacity of 10,000 tons of p-hydroxybenzoic acid, 3,000 tons of p-methoxybenzoic acid, 1,500 tons of p-hydroxybenzonitrile, 2,000 tons of parabens, and 800 tons of methyl m-cyanomethylbenzoate, among other series products. The company has successfully obtained ISO9001, ISO45001, and ISO14001 management system certifications.


    Adhering to the concept of green development throughout its entire production and operational processes, the company has introduced advanced production equipment and processes, deepened the construction of a green manufacturing system, increased efforts in energy-saving and carbon-reduction technological transformations, and promoted the deep integration of digitalization, intelligence, and green manufacturing. This has laid a solid foundation for building a comprehensive industrial ecosystem centered on "green technology, green products, and green services."


    Guided by the philosophy of "driven by technological innovation, committed to quality and safety, centered on customer value, and grounded in sustainable development," the company upholds the principle of "innovation-driven, green progress." It strives to create value for customers, offering high-quality products to achieve mutual success and a brighter future together!

  • Inquiry History
    9 Inquiries
    Country Product Purchase Quantity Date Posted
    Egypt

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