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USP Standard Quetiapine fumarate CAS:111974-72-2 99.5% Pharmaceutical Grade API Raw Material buy - image1

USP Standard Quetiapine fumarate CAS:111974-72-2 99.5% Pharmaceutical Grade API Raw Material buy - image2

USP Standard Quetiapine fumarate CAS:111974-72-2 99.5% Pharmaceutical Grade API Raw Material buy - image3

USP Standard Quetiapine fumarate CAS:111974-72-2 99.5% Pharmaceutical Grade API Raw Material buy - image4

USP Standard Quetiapine fumarate CAS:111974-72-2 99.5% Pharmaceutical Grade API Raw Material

Name: USP Standard Quetiapine fumarate CAS:111974-72-2 99.5% Pharmaceutical Grade API Raw Material
Brand: HyperChem
SKU: pr2512291239
Price: 2.8 USD
Availability: InStock

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Unit Price:

$2.8-3.5/G FOB

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CAS No.:

111974-72-2

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1kg/bag, 5kg/bag, 25kg/Drum

Price valid (until):

2027-05-31

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Quetiapine fumarate
CAS number	111974-72-2
Synonym	Quetiapine fumarate; 111974-72-2; Quetiapine hemifumarate;ICI-204636
Description	Quetiapine fumarate, with the CAS number 111974-72-2, is a well-established pharmaceutical compound primarily known for its application in the treatment of various psychiatric disorders. It is a powerful atypical antipsychotic agent that belongs to a class of medications specifically designed to manage conditions such as schizophrenia, bipolar disorder, and, in some cases, major depressive disorders. This compound functions through a complex mechanism of action attributed to its interaction with multiple neurotransmitter receptors in the brain, delivering therapeutic effects that alleviate symptoms associated with these mental health disorders. Description: Quetiapine fumarate is a white to off-white, crystalline powder with minimal solubility in water. It is commonly administered in tablet form for oral consumption. The medication has a distinctive chemical architecture that allows it to traversely engage with various neuronal receptors, contributing to its broad therapeutic abilities. Quetiapine fumarate is available in various dosage strengths to meet the needs of different patient conditions, ensuring tailored treatment and management plans. Mechanism of Action: The therapeutic advantages of Quetiapine fumarate derive from its antagonistic action on a multitude of neurotransmitter receptors in the central nervous system. Its primary targets include the serotonin 5-HT2A receptors and the dopamine D2 receptors. The drug's ability to modulate these receptors is central to its efficacy; by inhibiting the 5-HT2A receptors and wielding partial antagonism on D2 receptors, Quetiapine fumarate helps rebalance neurotransmitter levels in the brain, which can be disrupted in psychiatric disorders. Additionally, Quetiapine fumarate exhibits affinity towards other receptors, such as histamine H1 and adrenergic alpha-1 receptors, further contributing to its pharmacological profile. The blockade of these receptors can lead to various side effects, such as sedation and orthostatic hypotension, which are dose-dependent and should be carefully managed by healthcare professionals. Usage: Quetiapine fumarate is principally employed in the management of schizophrenia—a chronic mental disorder characterized by distorted thinking, perceptions, and emotional responsiveness. By normalizing neurotransmitter activity, Quetiapine fumarate aids in reducing hallucinations, improving concentration, and clarifying cognitive processes. It is also prescribed for treating the manic and depressive episodes associated with bipolar disorder. When used in this capacity, Quetiapine fumarate helps stabilize mood swings, enhancing overall quality of life and functional capabilities in affected individuals. In recent years, Quetiapine fumarate has found adjunctive use in the treatment of major depressive disorder, particularly in cases where first-line antidepressants fail to deliver satisfactory outcomes. Its antidepressant effects are believed to arise out of its serotonergic and dopaminergic modulation, providing an alternative pathway for alleviating depressive symptoms. Chemical Classification: Quetiapine fumarate belongs to the chemical class known as dibenzothiazepines. This distinctive chemical framework is integral to its interaction with various neurotransmitter receptors, underpinning its pharmacological efficacy. Additional Information: Safety and tolerability are crucial considerations in the use of Quetiapine fumarate. Common side effects include dizziness, dry mouth, and sedation, and though mostly mild to moderate, these should be closely monitored. In some cases, the medication may lead to more serious side effects, such as metabolic changes or heightened suicidal thoughts, especially in younger patients. Thus, regular follow-ups and observations are recommended to ensure safe usage. The versatility of Quetiapine fumarate in treating multiple mental health conditions underscores its importance in psychiatric pharmacotherapy. However, the effectiveness and safety of Quetiapine fumarate should always be evaluated against individual patient scenarios, making personalized medical guidance essential. Clinical studies have consistently supported the use of Quetiapine fumarate as a reliable therapy for psychiatric conditions, but they also highlight the necessity for meticulous dose adjustments and monitoring. Medical professionals often undertake a comprehensive assessment of each patient, considering factors such as age, physical health, and concurrent medications, before prescribing Quetiapine fumarate. In conclusion, Quetiapine fumarate stands as a cornerstone in the management of complex psychiatric disorders, offering relief and improved functioning for millions worldwide. Its profound impact is a testament to the advances in medicinal chemistry and the continuing endeavor to understand and refine therapeutic approaches to mental health. As ongoing research explores new facets of its mechanism and applications, Quetiapine fumarate remains a vital tool in the psychiatric therapeutic arsenal.

Molecular Formula	C ₂₅ H ₂₉ N ₃ O ₆ S
Molecular Weight	499.58 g/mol
Appearance	White or almost white crystalline powder
Quality Standard	USP EP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 2~8 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Fiber drum
Origin	China

Product Image

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FAQ

Q1. What is the Hyper chem payment term?
T/T advance
LC at sight
DP at sight
Trade assurance
Money gram

Q2. What is Hyper chem shipment policy?
Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
For non-ready stock, please contact the Hyper Chem sales team to negotiate.

Q3. What hyper chem will provide after shipment?
For sample orders:
After shipment is done, an timely email including:

Track details (Fedex /TNT/DHL/EMS Track number)

Package photo

COA, MSDS, etc

Dispatch date & Estimated arriving time

Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided
in scan-copy and original, to help customers complete the customs clearance process.

Q4. What is Hyper Chem shipment term?

By Express
DHL  FedEx  TNT  EMS
Fast:5 days around
High cost, door to door service

By Air
Suitable for more than 50kg
Fast :3-7 days Hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Slow:7-45 days, Low cost, port to port, professional broker needed
We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. Does hyper chem provide a shipment return policy?
Yes, we have.
Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied within 45 days of purchase for a full refund to:

Q6. What is hyper chem After-sales service
•Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
• Customer Support: Shipment clearance support, quality issue support
• Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.

Company profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

Certificates

Basic Info

Product Name:

Quetiapine fumarate

Other Name:

Ethanol,2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-,(2E)-2-butenedioate (2:1);Ethanol,2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-,(E)-2-butenedioate (2:1) (salt);Ethanol,2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-,(2E)-2-butenedioate (2:1) (salt);Dibenzo[b,f][1,4]thiazepine,ethanol deriv.;ICI 204636;Seroquel;ZM 204636;Quetiapine fumarate;ZD 5077;Quetiapine hemifumarate;Loquen;Quitpin;Quetros;Kwetaplex

CAS No.:

111974-72-2

Molecular Formula:

C21H25N3O2S.¹/2C4H4O4

InChIKeys:

InChIKey=VRHJBWUIWQOFLF-WLHGVMLRSA-N

Molecular Weight:

883.09

Exact Mass:

383.166748

EC Number:

1308068-626-2

HScode:

29349990

Categories:

Nervous System Drugs

Characteristics

PSA:

221.80000

XLogP3:

4.04660

Appearance:

Solid

Melting Point:

174-176°C

Boiling Point:

556.5ºC at 760 mmHg

Flash Point:

9℃

Water Solubility:

DMSO: >10mg/mL

Storage Conditions:

-20°C Freezer

Vapor Pressure:

5.39X10-14 mm Hg at 25 °C (est)

PKA:

7.06None

See More Quetiapine fumarate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Quetiapine fumarate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Quetiapine Fumarate	400 MG	May 29, 2026

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