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Home > Active Pharmaceutical Ingredients > Antibiotics > (6R,7R)-7-Amino-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid for Sale > High Purity 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA) Fast Shipment CAS 79349-82-9 Factory Supply Low Cost
High Purity 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA) Fast Shipment CAS 79349-82-9 Factory Supply Low Cost buy - large image1
High Purity 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA) Fast Shipment CAS 79349-82-9 Factory Supply Low Cost buy - image1
High Purity 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA) Fast Shipment CAS 79349-82-9 Factory Supply Low Cost buy - image2
High Purity 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA) Fast Shipment CAS 79349-82-9 Factory Supply Low Cost buy - image3
High Purity 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA) Fast Shipment CAS 79349-82-9 Factory Supply Low Cost buy - image4
High Purity 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA) Fast Shipment CAS 79349-82-9 Factory Supply Low Cost buy - image5
High Purity 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA) Fast Shipment CAS 79349-82-9 Factory Supply Low Cost buy - image6

High Purity 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA) Fast Shipment CAS 79349-82-9 Factory Supply Low Cost

Unit Price:

$12-13/KG FOB

Get Latest Price
CAS No.:

79349-82-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

WANWEI

Packaging:

25kg/Cardboard Drum

Price valid (until):

2026-07-26

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Tirzepatide,Retatrutide,Semaglutide

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    *Product Photos

    Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 1 Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 2 Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 3 Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 4 Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 5 Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 6 Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 7 Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 8 Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 9

    Product Introduction

    Item 7-Amino-3-vinyl-3-cephem-4-carboxylic acid (7-AVCA)
    Cas No. 79349-82-9
    Purity >99

    1. Product Overview


    7-Amino-3-vinyl-3-cephem-4-carboxylic acid (CAS No.: 79349-82-9), abbreviated as 7-AVCA, is a core key intermediate for third and fourth-generation cephalosporin antibiotics, widely applied in pharmaceutical raw material production. It appears as a white to off-white crystalline powder with high purity, excellent chemical stability under standard storage conditions and moderate water solubility. As a high-quality semi-synthetic β-lactam intermediate, it is the critical precursor for synthesizing broad-spectrum cephalosporin antibiotics, with stable structural properties and high reactivity, which can effectively ensure the quality and antibacterial efficacy of the final antibiotic products. The product is manufactured in strict compliance with GMP pharmaceutical quality standards, with a purity of ≥98% (HPLC), featuring stable and reliable performance, and can fully meet the application requirements of pharmaceutical production, antibiotic R&D and related bulk drug manufacturing.

    2. Mechanism of Action


    As a core intermediate of cephalosporin antibiotics, 7-AVCA itself has no direct bactericidal activity, and its functional mechanism is reflected in the synthesis of final antibiotic products. The 7-AVCA molecule contains a complete β-lactam ring and cephem core structure, which can be further modified and synthesized into finished cephalosporin antibiotics. The finished products bind to penicillin-binding proteins (PBPs) on the cytoplasmic membrane of sensitive bacteria, inhibit the synthesis of bacterial cell wall peptidoglycan, interfere with the cross-linking of peptidoglycan chains, lead to defective bacterial cell wall structure, make bacteria lose osmotic pressure balance, swell and rupture, and finally achieve the bactericidal effect. The high structural stability of 7-AVCA can ensure that the final synthesized cephalosporins have strong resistance to β-lactamases and broad antibacterial spectrum.

    3. Core Functions & Application Advantages


    Core functional positioning


    It is a key precursor for synthesizing third and fourth-generation cephalosporin antibiotics, and is indispensable for producing high-efficiency broad-spectrum cephalosporin bulk drugs, such as cefixime, cefdinir and cefetamet pivoxil.

    Excellent structural stability


    It has a stable β-lactam ring structure, strong resistance to acid and partial enzymes, is not easy to decompose during the synthesis process, and can ensure the high yield and high purity of the final antibiotic products.

    High reactivity and compatibility


    It has good chemical reactivity, can be compatible with various side chain modification reactions, and is suitable for the production of various types of cephalosporin preparations (oral, injection, etc.), meeting the diversified production needs of pharmaceutical enterprises.

    High purity and reliable quality


    The product purity is ≥98% (HPLC), with low impurity content, no adverse effects on the subsequent synthesis process, and can effectively reduce the production cost of finished drugs and improve the production efficiency of enterprises.

    4. Application Scope


    7-AVCA is a high-value pharmaceutical intermediate, mainly used as a core raw material for the synthesis of third and fourth-generation cephalosporin antibiotics, covering pharmaceutical production, R&D and other fields, with a wide range of applications:

    Synthesis of oral cephalosporin antibiotics


    It is used to produce oral broad-spectrum cephalosporins such as cefixime and cefdinir, which are widely used in the clinical treatment of respiratory tract, urinary tract, digestive tract and other bacterial infections.

    Synthesis of injectable cephalosporin antibiotics


    As a key raw material for injectable cephalosporins, it is involved in the production of high-efficiency cephalosporin preparations for the treatment of moderate to severe bacterial infections such as sepsis, pneumonia and abdominal infection.

    Pharmaceutical R&D field


    It is an important experimental raw material for pharmaceutical enterprises and research institutions to develop new cephalosporin antibiotics, and is used for the structural modification and efficacy optimization of new antibiotic products.

    Bulk drug production


    It is the core intermediate for large-scale production of cephalosporin bulk drugs, and is widely used in the production line of pharmaceutical enterprises, meeting the market demand for high-quality cephalosporin antibiotics.

    5. Usage Precautions & Matters Needing Attention


    Operational precautions


    This product is a pharmaceutical intermediate, which should be operated by professional personnel with relevant qualifications; operators should wear protective equipment such as masks, gloves and protective clothing during operation to avoid direct contact with skin and mucous membranes.

    It should be used in a well-ventilated and dust-free workshop to prevent dust leakage and inhalation; the operation should be carried out in accordance with the pharmaceutical production specifications to ensure the purity of the product during use.

    Compatibility matters


    It should not be mixed with strong acids, strong bases, oxidants and other incompatible substances during use to avoid chemical reactions, which will lead to product structure damage and performance failure.

    During the synthesis reaction, it should be used in strict accordance with the process formula, and the reaction conditions such as temperature and pH should be controlled to ensure the smooth progress of the synthesis reaction.

    Special tips for users


    This product is only used for the production and R&D of pharmaceutical products, and is not for direct clinical use or human and animal administration.

    Pharmaceutical enterprises should conduct strict quality inspection before use to ensure that the product indicators meet the production requirements; if there are abnormal conditions such as discoloration and agglomeration, it should be stopped using immediately.

    Waste disposal


    The waste generated during the use process should be treated in accordance with the relevant national pharmaceutical waste disposal standards, and should not be discharged at will to avoid environmental pollution; the packaging materials should be recycled and treated centrally to meet the environmental protection requirements.

    6. Storage Conditions


    Store in a cool, dry and well-ventilated warehouse, away from direct sunlight, high temperature and open fire;

    Strictly control the storage temperature between 2℃ and 8℃, freezing is strictly prohibited to prevent the destruction of the product's chemical structure and affect the subsequent synthesis effect;

    Keep the inner and outer packages tightly sealed to prevent the product from absorbing moisture, oxidizing, deliquescing and being contaminated by microorganisms, so as to avoid the reduction of purity;

    Store separately from toxic, harmful, corrosive, strong oxidizing and incompatible substances, and strictly prohibit mixed storage and transportation to avoid chemical reactions;

    The shelf life is 24 months under the specified storage conditions; do not use the product if it exceeds the expiration date indicated on the package;

    During transportation, take anti-shock, anti-pressure and strict temperature control measures to ensure that the transportation environment meets the storage temperature requirements, avoid package damage and product deterioration, and conduct regular temperature monitoring during long-distance transportation.

    Shop N-Ethyl-3-cyano-4-methyl-6-hydroxy-2-pyridone CAS 29097-12-9 Factory Direct Supply High Quality Low Price-Detailed Image 10

    Basic Info
    Product Name:

    (6R,7R)-7-Amino-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

    Other Name:

    5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-amino-3-ethenyl-8-oxo-,(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-amino-3-ethenyl-8-oxo-,(6R-trans)-;(6R,7R)-7-Amino-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;7-Amino-3-vinyl-3-cephem-4-carboxylic acid

    CAS No.:

    79349-82-9

    Molecular Formula:

    C9H10N2O3S

    InChIKeys:

    InChIKey=GQLGFBRMCCVQLU-SVGQVSJJSA-N

    Molecular Weight:

    226.25

    Exact Mass:

    226.25

    EC Number:

    1592732-453-0

    DSSTox ID:

    DTXSID80428501

    Categories:

    Antibiotics

    Characteristics
    PSA:

    109

    XLogP3:

    -2.8

    Density:

    1.6±0.1 g/cm3

    Melting Point:

    >200 °C (decomp)

    Boiling Point:

    540.7°C at 760 mmHg

    Flash Point:

    280.8±30.1 °C

    Refractive Index:

    1.696

    Storage Conditions:

    -20°C Freezer

    Hazard Identification

    Classification of the substance or mixture

    Skin sensitization, Category 1

    Respiratory sensitization, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H317 May cause an allergic skin reaction

    H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled

    Precautionary statement(s)
    Prevention

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P284 [In case of inadequate ventilation] wear respiratory protection.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P321 Specific treatment (see ... on this label).

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Tirzepatide,Retatrutide,Semaglutide

    Location:

    No. 2302, Changqing Road, Gaoyuan Community, Laodaohe Sub-district, Kaifu District, Changsha City, Hunan Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    101-200

    Year of Establishment:

    2023

    Changsha Wanwei Technology Co., Ltd. has been deeply engaged in the biopharmaceutical industry for over 20 years and stands as a global leader in the metabolic disease drug sector. Leveraging its integrated end-to-end capabilities covering "R&D, production, and commercialization" as well as profound industry expertise, the company firmly ranks among the top tier of the global biopharmaceutical industry. Its core products include multiple key varieties such as Semaglutide, Tirzepatide, Retatrutide, and Cagrilintide.​
    Eighty percent of the members in the company's core team possess over 15 years of experience in metabolic drug R&D. Many of them have led the launch of internationally blockbuster antidiabetic drugs. The team has successfully facilitated the approval of 12 innovative drugs, among which 5 have become top 50 best-selling prescription drugs globally. This has enabled the company to establish an irreplicable technical and experiential barrier in fields such as peptide drug molecular modification and long-acting formulation development.​
    On the R&D front, the company has built four national-level technology platforms, including peptide molecular design and oral formulation innovation, and holds more than 300 authorized patents. Its drug R&D cycle is 30% shorter than the industry average. On the production side, it owns the world's largest intelligent base for peptide drugs, with an annual production capacity of 500 kilograms. The base complies with the triple GMP standards of China, the United States, and the European Union, and achieves a 90% self-sufficiency rate in key raw materials, ensuring stable supply to over 120 countries. Additionally, the company has passed the unannounced inspections by the FDA (U.S. Food and Drug Administration) and EMA (European Medicines Agency) for 10 consecutive years.​
    Currently, Semaglutide has overcome the challenge of low oral bioavailability, achieving global sales of over 15 billion US dollars within 3 years of its launch. Tirzepatide surpassed 8 billion US dollars in sales in its first year on the market. Retatrutide has entered Phase III clinical trials, while the combination therapy of Cagrilintide is in Phase II clinical development. All these products demonstrate revolutionary therapeutic value. Looking ahead, the company will invest 25% of its annual revenue in R&D, focusing on the fields of metabolism and cardiovascular diseases, and is committed to becoming a global innovation benchmark in the biopharmaceutical industry.

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