ISO high pure 99% Hydroxyurea powder CAS 127-07-1 Pharmaceutical Raw material
TDS
127-07-1
Pharmaceutical Grade
99%
SHANGHAI/SHENSHEN/GUANGZHOU/SHENZHEN/QINGDAO
HNB-BIOTECH
25kg/carton drum; 1kg/aluminium foil bag
2026-04-30
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceIt appears as white needle-like crystals with the melting point being 70-72 ℃ (decomposition) or 141 ℃ (decomposition). It is easily soluble in hot water and ethanol, slightly soluble in cold ethanol, insoluble in ether, benzene. It is unstable when coming across water or heat. It is odorless and tasteless. Off-White Crystalline SolidOdorless or almost odorless white to off-white crystalline solid. Tasteless. HONH-CO-NH2. The drug is available in a 500-mg capsulefor oral use.
Hydroxyurea appears as odorless or almost odorless white to off-white crystalline solid. Tasteless. (NTP, 1992)|Solid
Hydroxyurea appears as odorless or almost odorless white to off-white crystalline solid. Tasteless. (NTP, 1992)|Hydroxyurea is a member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease. It has a role as a DNA synthesis inhibitor, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor, an antineoplastic agent, a genotoxin, an antimetabolite, a teratogenic agent, a radical scavenger, an immunomodulator and an antimitotic. It is a member of ureas and a one-carbon compound.|An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.|Hydroxyurea is an Antimetabolite.|Hydroxyurea is an antimetabolite that is used in the treatment of cancer and to stimulate fetal hemoglobin production in sickle cell disease. Hydroxyurea is associated with a low rate of transient serum enzyme and bilirubin elevations during therapy, and has been implicated in rare cases of clinically apparent acute liver injury with jaundice.|Hydroxyurea is a monohydroxyl-substituted urea (hydroxycarbamate) antimetabolite. Hydroxyurea selectively inhibits ribonucleoside diphosphate reductase, an enzyme required to convert ribonucleoside diphosphates into deoxyribonucleoside diphosphates, thereby preventing cells from leaving the G1/S phase of the cell cycle. This agent also exhibits radiosensitizing activity by maintaining cells in the radiation-sensitive G1 phase and interfering with DNA repair. (NCI04)CertificatesBasic Info-
Product Name:
Hydroxyurea
Other Name:Urea,N-hydroxy-;Urea,hydroxy-;N-Hydroxyurea;SQ 1089;NSC 32065;Carbamohydroxamic acid;HU;Hydrea;Hydroxycarbamide;Hydroxylurea;Hydroxyurea;Hydroxylamine,N-(aminocarbonyl)-;Carbamoyl oxime;Carbamohydroximic acid;Hydroxycarbamine;Litaler;Oxyurea;Hidrix;Hydreia;Hydura;Litalir;Onco-Carbide;Biosupressin;NCI C04831;N-Carbamoylhydroxylamine;Hydurea;SK 22591;Oxyrea;Droxia;Cytodrox;Siklos;Mylocel;1-Hydroxyurea;Xromi
CAS No.:127-07-1
Molecular Formula:CH4N2O2
InChIKeys:InChIKey=VSNHCAURESNICA-UHFFFAOYSA-N
Molecular Weight:76.05
Exact Mass:76.05
BRN:1741548
EC Number:204-821-7
UNII:X6Q56QN5QC
NSC Number:757072|32065
UN Number:2811
DSSTox ID:DTXSID6025438
NCI Thesaurus Code:C560
Color/Form:Needles from alcohol|White, crystalline powder|Needles from ethanol, crystals in 2 forms
ATC Code:L01XX05|L - Antineoplastic and immunomodulating agents
HScode:29242100
Categories:
Characteristics-
PSA:
75.4
XLogP3:-1.6
Appearance:white powder
Density:1.457±0.06 g/cm3(Predicted)
Melting Point:141 °C
Boiling Point:Decomposes
Refractive Index:1.4840 (estimate)
Water Solubility:H2O: soluble
Storage Conditions:2-8°C
Vapor Pressure:2.43X10-3 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 5.42X10-11 atm-cu m/mole at 25 °C (est)
Experimental Properties:Crystals in 2 forms. MP form 1: 70-72 °C (decomposes); MP form 2: 141 °C|Moisture-labile|Hydroxyl radical reaction rate constant = 2.00X10-12 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions:Water soluble.
Reactive Group:Alcohols and Polyols
Reactivity Profile:An amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Hazard IdentificationClassification of the substance or mixture
Germ cell mutagenicity, Category 1B
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H340 May cause genetic defects
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature 2 - 8 deg C. Moisture sensitive. Keep in a dry place.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive
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Location:
6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China
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Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2017
Company Certificates-
ISO
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ISO
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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