3,4,5-Trimethoxybenzoic Acid

3,4,5-Trimethoxybenzoic Acid is a high-quality aromatic carboxylic acid used as a fine chemical intermediate, pharmaceutical intermediate, organic synthesis building block, and research reagent. It is also known as eudesmic acid, gallic acid trimethyl ether, and trimethylgallic acid. PubChem lists the compound with CAS number 118-41-2, molecular formula C₁₀H₁₂O₅, and synonyms including 3,4,5-trimethoxybenzoic acid and gallic acid trimethyl ether. 

This product is suitable for manufacturers and laboratories requiring a reliable trimethoxy-substituted benzoic acid intermediate for controlled synthesis, specialty chemical development, and high-value derivative production.

Key Product Information

Commercial reagent specifications commonly list this material at 99% assay, with a melting point of 168–171 °C and boiling point of 225–227 °C at 10 mmHg, depending on grade and supplier specification. 

Key Features

Typical Applications

Pharmaceutical Intermediate Development

3,4,5-Trimethoxybenzoic Acid is commonly used as a pharmaceutical and fine chemical intermediate. Patent literature describes it as an intermediate useful for medicines such as trimethoprim, making it valuable for pharmaceutical intermediate synthesis and related chemical development.

Organic Synthesis

The compound contains both a carboxylic acid group and a 3,4,5-trimethoxy-substituted aromatic ring, allowing it to be used in esterification, amidation, salt formation, reduction, and other synthetic transformations. This makes it a practical starting material for producing aromatic esters, amides, benzyl derivatives, and other specialty compounds.

Fine Chemical Production

3,4,5-Trimethoxybenzoic Acid is used in fine chemical manufacturing where a defined trimethoxybenzoic acid structure is required. ChemicalBook describes it as an important fine chemical product or pharmaceutical intermediate used in medicine, dyes, food-related fields, and the fine chemical industry.  

Dye and Specialty Chemical Applications

Its methoxy-substituted aromatic structure makes it suitable for dye intermediates, color-related chemical systems, and specialty aromatic compound development.

Research and Laboratory Use

This material is suitable for laboratory research, analytical studies, reaction development, impurity research, reference-related work, and custom synthesis projects.

Formulation and Processing Benefits

3,4,5-Trimethoxybenzoic Acid provides a useful balance of aromatic stability, carboxylic acid reactivity, and methoxy-substituted ring functionality. It is especially suitable for customers developing:

Pharmaceutical intermediates requiring trimethoxy aromatic functionality.
Fine chemical derivatives such as esters, amides, and substituted aromatic compounds.
Custom synthesis products for research and development.
Dye and specialty intermediates requiring controlled aromatic substitution.
Laboratory reagents for reaction screening and method optimization.

Packaging and Storage

Store 3,4,5-Trimethoxybenzoic Acid in a cool, dry, and well-ventilated area. Keep the container tightly closed after opening. Protect the product from moisture, heat, direct sunlight, ignition sources, and incompatible materials. Supplier safety information classifies the material under combustible solids, so appropriate industrial handling procedures and personal protective equipment should be used.  

Suggested Short Listing Copy

3,4,5-Trimethoxybenzoic Acid is a high-quality aromatic carboxylic acid used as a pharmaceutical intermediate, fine chemical intermediate, and organic synthesis building block. Also known as eudesmic acid or gallic acid trimethyl ether, it is suitable for the production of specialty chemicals, aromatic derivatives, dye intermediates, research compounds, and custom synthesis products.

Conclusion

3,4,5-Trimethoxybenzoic Acid is a dependable and versatile intermediate for pharmaceutical, fine chemical, dye, and research applications. Its trimethoxy-substituted aromatic structure and carboxylic acid functionality make it an effective raw material for producing high-value derivatives and specialty compounds. Overall, it is a practical choice for manufacturers and laboratories seeking a reliable building block for advanced organic synthesis.