Rutin

Rutin is a high-quality natural flavonoid glycoside widely used in dietary supplements, functional foods, cosmetics, personal care products, pharmaceutical intermediates, and research formulations. Also known as quercetin-3-rutinoside or rutoside, Rutin is structurally related to quercetin and is valued for its antioxidant properties, botanical origin, and broad formulation flexibility. PubChem describes Rutin as a rutinoside formed from quercetin with glucose and rhamnose sugar groups attached at the C-3 position.  

Rutin is especially suitable for manufacturers looking for a plant-based flavonoid ingredient for antioxidant-positioned products, botanical blends, beauty-from-within supplements, skincare formulations, and specialty active ingredient systems.

Key Product Information

MilliporeSigma lists Rutin under CAS number 153-18-4 and identifies common synonyms including quercetin 3-rutinoside, rutoside, and related flavonoid names.  

Key Features

Typical Applications

Dietary Supplements

Rutin is commonly used in capsules, tablets, soft capsules, drink powders, and botanical blends. It is suitable for supplement formulas positioned around flavonoids, antioxidants, plant polyphenols, and natural active ingredients.

Functional Food and Beverage

Rutin may be used in suitable functional food and beverage applications where a natural flavonoid ingredient is required. It can be incorporated into powders, nutrition mixes, wellness drinks, and other botanical formulations, subject to local food regulations.

Cosmetics and Personal Care

Rutin can be used in creams, lotions, serums, masks, and other personal care products where antioxidant and skin-conditioning positioning is desired. The European Commission CosIng database lists RUTIN as a cosmetic ingredient with CAS numbers 153-18-4 / 130603-71-4 and EC number 205-814-1.  

Pharmaceutical and Fine Chemical Intermediates

Rutin is also used as a flavonoid raw material and intermediate for further processing, derivative development, and specialty chemical applications.

Research and Laboratory Use

Rutin is widely used in research related to flavonoids, natural products, antioxidants, plant extracts, and analytical reference work.

Formulation Benefits

Rutin is a versatile ingredient for manufacturers developing natural, plant-based, and antioxidant-positioned products. Its flavonoid structure makes it useful in formulas that combine botanical extracts, vitamins, polyphenols, and functional plant compounds.

It is especially suitable for:

Capsules and tablets containing flavonoid or antioxidant blends.
Powder drink mixes and functional nutrition products.
Beauty-from-within formulas using botanical active ingredients.
Skincare products such as creams, serums, masks, and lotions.
Research formulations requiring a quercetin-related flavonoid compound.

Regulatory Note

Rutin use should follow the applicable regulations in the destination market, especially for food, supplement, cosmetic, and pharmaceutical applications. The European Commission notes that inclusion of an ingredient in the CosIng inventory is for information purposes and is not itself an indication of authorization; finished-product compliance must be assessed according to the relevant cosmetic regulation and local requirements.  

Packaging and Storage

Store Rutin in a cool, dry, and well-ventilated area. Keep the container tightly closed after opening. Protect from moisture, heat, direct sunlight, and strong oxidizing materials. For best results, use proper handling procedures and follow the relevant Safety Data Sheet.

Suggested Short Listing Copy

Rutin is a natural flavonoid glycoside, also known as quercetin-3-rutinoside or rutoside, used in dietary supplements, functional foods, cosmetics, personal care products, pharmaceutical intermediates, and research applications. With its antioxidant profile, botanical origin, and excellent formulation flexibility, Rutin is an ideal ingredient for plant-based, flavonoid-rich, and antioxidant-positioned product development.

Conclusion

Rutin is a reliable and multifunctional botanical ingredient suitable for a wide range of supplement, cosmetic, food, and specialty formulation applications. Its natural flavonoid identity, quercetin-related structure, and antioxidant positioning make it a valuable choice for manufacturers developing modern plant-based and functional products.