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Retatrutide 99%Freeze-dried powder In stock Minimum Order Hot Selling

TDS 6519 Inquiries

Unit Price:

$47/UNIT FOB

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CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Tianjin (CNTJ)

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2027-08-15

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Anhui Ruibang Trading Co., Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

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Product Description
Seller Information
Inquiry History

Description

Items	Specifications
Product Name	Retatrutide
Purity	≥98% (HPLC)
Appearance	White to off‑white lyophilized powder
Storage	−20°C, sealed, dry, avoid light
Shelf Life	24 months under proper storage
Quality Standard	HPLC tested, complete COA provided

Product Detail

RT Peptide (Retatrutide, short for Reta/GLP-3RT) is a new-generation metabolic regulatory peptide, mainly applied in weight loss and blood sugar regulation.

1. Basic Molecular Parameters (Industry Standard)

Full Name: Retatrutide

Amino Acid Sequence: H-His¹-Gly²-Glu³-Gly⁴-Thr⁵-Phe⁶-Thr⁷-Ser⁸-Asp⁹-Lys¹⁰(PEG27)-Ala¹¹-Gln¹²-Thr¹³-Phe¹⁴-Val¹⁵-Gly¹⁶-Glu¹⁷-Gly¹⁸-Pro¹⁹-Ser²⁰-Ser²¹-Gly²²-Ala²³-Pro²⁴-Pro²⁵-Ser²⁶-Lys²⁷-OH

Molecular Formula: C₁₉₁H₂₉₇N₅₅O₆₇S

Molecular Weight: ~4633 g/mol

CAS Number: 2787973-52-9

Appearance: Sterile lyophilized white/off-white powder, vial packaging (common specs: 5mg / 10mg per vial)

Purity: ≥98.0% tested by HPLC; each batch is attached with full COA, HPLC chromatogram and MSDS

R&D Background: Retatrutide is a novel triple receptor agonist targeting GLP‑1R, GIPR and GCGR, developed for metabolic disorder preclinical research. It is a long-acting PEGylated synthetic peptide with balanced activation of three key metabolic hormone receptors.

2. Core Mechanism of Action

Retatrutide is a balanced triple agonist of GLP‑1, GIP and glucagon receptors, regulating multi-organ metabolic pathways simultaneously:

Activate GLP‑1R to suppress appetite, slow gastric emptying and reduce caloric intake; improve insulin secretion in a glucose-dependent manner;
Stimulate GIPR to enhance pancreatic β-cell function, boost insulin sensitivity and reduce hepatic glucose output;
Moderately activate GCGR to increase energy expenditure via hepatic fat oxidation and lipolysis;
Reduce visceral adipose tissue accumulation by inhibiting adipocyte differentiation;
Lower circulating triglycerides, LDL and liver lipid deposition to alleviate hepatic steatosis;
Regulate central hypothalamic appetite circuits for sustained weight-lowering effects.

3. Core Research Efficacy (For Laboratory Research Only)

Weight Management & Obesity Research

Induce significant, sustained body weight loss in obese animal models; ideal reagent for studies on adiposity, fat metabolism and anti-obesity drug screening.

Type 2 Diabetes & Insulin Resistance

Stabilize blood glucose levels, improve HbA1c and peripheral insulin sensitivity; widely applied in diabetic rodent cell & animal experimental models.

Non-Alcoholic Fatty Liver Disease (NAFLD)

Reduce hepatic lipid buildup, relieve hepatic steatosis and hepatic inflammation; support research on metabolic liver injury repair.

Cardiometabolic Risk Improvement

Lower blood lipid levels and alleviate metabolic-related vascular dysfunction; used for preclinical research on metabolic cardiovascular complications.

Compliance Disclaimer

This product is for laboratory research use only. It shall not be used for human injection, oral administration or clinical medical treatment. All descriptions are based on preclinical experimental data and do not constitute therapeutic medical claims.

About us

Anhui Ruibang Trading Co., Ltd. was established with a clear mission: to simplify international trade for businesses of all sizes. We act as a bridge between manufacturers and global buyers, offering professional sourcing, quality inspection, order coordination, and logistics management.

Our team brings years of experience in cross-border trade, supplier networks, and export documentation. We understand the challenges of international business — language barriers, quality control, shipping complexities — and we solve them with a client-first approach.
At Ruibang Trading, we don’t just move goods; we build relationships. Whether you are looking for a reliable supplier, need help consolidating shipments, or want to expand your product line, we provide tailored solutions to meet your goals.
Our Commitment: Integrity, efficiency, and transparency in every transaction.

Why choose us

Our products are of reliable quality and sell well all over the world, with partners across many countries and regions. We have professional technical support and complete after-sales teams to promptly respond to all your inquiries and demands.

We always strictly control product quality, adhere to honest business principles, and prioritize quality and service. With stable product strength and thoughtful services, we sincerely welcome global customers to negotiate cooperation and achieve win-win development together.

We have been deeply engaged in the peptide industry for many years, serving as a source biotechnology factory integrating R&D, synthesis, production and sales.

We strictly follow production and quality control standards, with the whole process adopting aseptic production and independent lyophilization and packaging. Our products feature stable appearance, good solubility and high activity retention.

We support trial orders with small quantities, bulk orders and customized formulas, providing one-stop solutions for foreign trade supply and private customization needs.

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Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.

Certificates

Basic Info

Product Name:

Retatrutide

Other Name:

Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

CAS No.:

2381089-83-2

Molecular Formula:

C221H342N46O68

Molecular Weight:

4731.33

EC Number:

200-001-8

Color/Form:

White lyophilized

Categories:

Bulk Drug Intermediates

Characteristics

Water Solubility:

Soluble in water (5mg/ml).

Storage Conditions:

-20°C

Critical Temperature & Pressure:

-20°C

Research

Class:

Triple agonist — GCGR, GIPR, GLP-1R

Status:

Investigational (Phase 3)

Mechanism:

Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

EC50 (Human GCGR):

5.79 nM

EC50 (Mouse GIPR):

0.191 nM

EC50 (Mouse GLP1R):

0.794 nM

EC50 (Mouse GCGR):

2.32 nM

EC50 (Human GLP1R):

0.775 nM

EC50 (Human GIPR):

0.0643 nM

Source:

Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

Clinical Development:

NCT04881760; NCT05882045; NCT06354660

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Jastreboff et al. (2023) — Phase 2 Trial; FDA Drugs@FDA

Disclaimer:

Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

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Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

Location:
Hefei, Provincia de Anhui

Year of Establishment:
2026

Inquiry History

6519 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Retatrutide 2381089-83-2	3 MT	Mar 28, 2026
United Kingdom	Retatrutide - 2381089-83-2	1 G	Feb 10, 2026
United States	Retatrutide CAS 2381089-83-2 10mg vial	20 MT	Mar 7, 2026
United States	Factory Retatrutide API 99% Purity CAS 2381089-83-2	5 KG	Nov 10, 2025
United Kingdom	Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA	1 MT	Mar 22, 2026
United States	2381089-83-2	100 G	Jul 14, 2026
United States	2381089-83-2	100 G	Feb 24, 2026
United States	2381089-83-2	100 MT	Dec 9, 2023
United States	Retatrutide 2381089-83-2	200 MG	May 16, 2026
United Kingdom	2381089-83-2 retatrutide	300 MG	Feb 13, 2026
United States	Retatrutide 2381089-83-2 wholesale	500 MT	Nov 3, 2023
Poland	CAS 2381089-83-2 (Custom Peptide)	40 MT	Apr 10, 2026
Austria	Peptide Retatruide CAS 2381089-83-2	100 MT	Apr 4, 2026
United States	Retatrutide CAS 2381089-83-2 99%	10 PCS	Feb 21, 2026
Austria	Retatrutide CAS 2381089-83-2 10mg vial	20 PCS	Feb 10, 2026
United States	Tirzepatide 99.9% Liquid 2381089-83-2 TeruiOP	1 MT	Sep 6, 2023
United States	Retatrutide/LY3437943/GIPR/GLP-1R 98% Powder 2381089-83-2 Senwayer	1 G	Sep 3, 2023
United States	GLP-1 / GIP Retatrutide cas 2381089-83-2	1 MT	Oct 16, 2024
United States	Retatrutide 99% High Quality CAS 2381089-83-2	1 G	Jan 23, 2026
United States	Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2	10	Oct 21, 2023

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