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Forkhead Box O4 99%Freeze-dried powder In stock Minimum Order Hot Selling

Name: Forkhead Box O4 99%Freeze-dried powder In stock Minimum Order Hot Selling
Brand: Pharma;Conutrix
SKU: pr2605121063
Price: 33 USD
Availability: InStock

TDS 26 Inquiries

Unit Price: Get Latest Price 

CAS No.:

2460055-10-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

TianJin

Brand:

Pharma;Conutrix

Packaging:

10 vials/box

Price valid (until):

2026-06-20

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Anhui Ruibang Trading Co., Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

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Product Description
Seller Information
Inquiry History

Description

  Product Detail

Basic Parameter Information

Full Name: Forkhead Box O4 (FOXO4)

Amino Acid Sequence: Full-length recombinant transcription factor polypeptide carrying the conserved FOX DNA-binding structural domain

Molecular Formula: Complex recombinant protein polypeptide sequence

Molecular Weight: ~52.8 kDa

CAS Number: Unassigned recombinant protein

Appearance: Sterile lyophilized off-white powder, packaged in vials (main specifications: 1mg / 5mg)

Purity: ≥95% as tested by SDS-PAGE & HPLC, COA quality inspection report attached for each batch

R&D Background: Forkhead Box O4 (FOXO4) is a member of the FOXO subgroup of highly conserved forkhead transcription factors found across mammalian tissues including muscle, nerve, fat and epithelial organs. It acts as a master epigenetic controller that governs cellular aging, response to oxidative stress, energy metabolism and programmed cell elimination. This lab-grade recombinant polypeptide is prepared for in vitro cell signal testing, aging pathway exploration and senescence-related research, widely adopted in biogerontology, cell metabolism and degenerative disease preclinical trials.

2. Core Mechanism of Action

FOXO4 shifts location between the cytoplasm and cell nucleus based on upstream growth factor signals, attaching to conserved FOX response segments on target gene promoters to govern downstream transcriptional networks:

When insulin and IGF-1 levels remain low, FOXO4 gathers inside the nucleus to trigger the expression of antioxidant genes such as SOD and GPx, cutting down excess reactive oxygen substances inside cells and relieving oxidative damage to cell structures;

It controls the expression of genes linked to senescence-associated secretory phenotype (SASP) and cell cycle block signals, serving as a key switch that governs the start and continuous state of cellular aging;

It coordinates the transcription of genes related to sugar and fat metabolism in liver and adipose tissue, balancing energy storage capacity, insulin responsiveness and whole-body nutrient utilization efficiency;

It interacts with p53 cell death signal chains to adjust the critical threshold for cell cycle pause and programmed cell removal triggered by external stress;

It adjusts self-renewal and differentiation signals of stem cells in muscle and nerve precursor cells, which shapes the tissue self-repair ability of organisms as they grow older;

When growth factor signals are abundant, FOXO4 moves out of the nucleus and stays within the cytoplasm, losing its ability to activate transcription and halting the expression of anti-aging and energy-breakdown gene programs.

3. Core Research Efficacy (For Research Laboratory Use Only)

Cellular Senescence & Anti-Aging Mechanism Research

Core lab reagent for exploring the onset of cell aging, SASP release and pathways for clearing aged cells; suitable for testing fibroblast aging and tissue degeneration models related to organ senescence.

Oxidative Stress & Antioxidant Pathway Research

Starts endogenous antioxidant gene programs to counteract cell damage brought by reactive oxygen species, supporting studies on free radical aging, radiation stimulation and oxidative tissue lesions.

Glucose & Lipid Metabolic Regulation Research

Manages the activation of liver sugar-production and fat-generation genes, key experimental raw material for signal tests around insulin insensitivity, metabolic syndrome and energy balance.

Stem Cell & Tissue Regeneration Research

Adjusts proliferation and differentiation signals of precursor cells, applied to research on muscle recovery, neural stem cell maintenance and age-related decline of tissue repair capacity.

Apoptosis & Tumor Suppressor Signaling Study

Works alongside p53 stress response networks to regulate cell survival and growth arrest, auxiliary testing material for DNA damage response and degenerative lesion mechanism analysis.

Supplied as sterile lyophilized powder, SDS-PAGE & HPLC purity ≥95%, mainstream vial specifications: 1mg, 5mg. Every batch is equipped with full COA, MSDS, SDS-PAGE electrophoresis and HPLC chromatogram test documents.

As a lab-use recombinant FOXO transcription factor reagent, FOXO4 acts as a core upstream linkage between growth factor signals, internal antioxidant defense, energy metabolism and cellular aging. Its reversible movement between cytoplasm and nucleus allows researchers to fully analyze the transcriptional chains that drive cell senescence, metabolic imbalance and multi-organ tissue degeneration in diverse cell types.

It serves as essential research material for in-vitro cell culture and tissue model experiments covering biogerontology, senescent cell clearance, oxidative stress resistance, sugar-lipid metabolism and stem cell regenerative biology.

Note: For laboratory research use only, not approved for human oral consumption or clinical therapeutic treatment.

We maintain sufficient stable stock, complete export certification documents, door-to-door double customs clearance service with full real-time tracking of all shipments.

  About us

Anhui Ruibang Trading Co., Ltd. was established with a clear mission: to simplify international trade for businesses of all sizes. We act as a bridge between manufacturers and global buyers, offering professional sourcing, quality inspection, order coordination, and logistics management.

Our team brings years of experience in cross-border trade, supplier networks, and export documentation. We understand the challenges of international business — language barriers, quality control, shipping complexities — and we solve them with a client-first approach.
At Ruibang Trading, we don’t just move goods; we build relationships. Whether you are looking for a reliable supplier, need help consolidating shipments, or want to expand your product line, we provide tailored solutions to meet your goals.
Our Commitment: Integrity, efficiency, and transparency in every transaction.

Why choose us

Our products are of reliable quality and sell well all over the world, with partners across many countries and regions. We have professional technical support and complete after-sales teams to promptly respond to all your inquiries and demands.

We always strictly control product quality, adhere to honest business principles, and prioritize quality and service. With stable product strength and thoughtful services, we sincerely welcome global customers to negotiate cooperation and achieve win-win development together.

We have been deeply engaged in the peptide industry for many years, serving as a source biotechnology factory integrating R&D, synthesis, production and sales.

We strictly follow production and quality control standards, with the whole process adopting aseptic production and independent lyophilization and packaging. Our products feature stable appearance, good solubility and high activity retention.

We support trial orders with small quantities, bulk orders and customized formulas, providing one-stop solutions for foreign trade supply and private customization needs.

Our Advantages

  Packaging Process:

Certificates
Basic Info

Product Name:
FOXO4-DRI

Other Name:
FOXO4-DRI;FOXO4 /FOXO4-DRI;FOX04-DRI (D-Retro-Inverso);Fox4-dri

CAS No.:
2460055-10-9

Molecular Weight:
0

Color/Form:
White to off-white

Categories:
Bulk Drug Intermediates

Characteristics
Seller Information

Business Type:
Trader

Main Products:
Retatrutide,Tirzepatide,Semaglutide,Cynomorium Songaricum Extract,Bull Penis Powder,Deer Penis Extract

Location:
Hefei, Provincia de Anhui

Year of Establishment:
2026

Inquiry History

26 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	FOXO4-DRI	1 G	Dec 3, 2023
United States	Fox04-dri	1 G	May 20, 2026
United States	hot-sale-high-purity-raw-powder-fox04-dri-nad-ghk-cu-mot	2 PCS	Dec 19, 2025
United States	foxo4 dri	10 MT	Dec 13, 2025
United States	Fox04	10 MG	Oct 30, 2024
United Kingdom	High purity foxo4	1 G	May 31, 2026
United Kingdom	Foxo4-Dri	10 MG	May 5, 2026
United States	Fox04-dri	100 MG	Apr 28, 2026
Cyprus	Foxo4 dri	10 MT	Apr 4, 2026
Cyprus	FOXO4-DRI	1 KG	Feb 2, 2026
United States	FOX04-DRI	10 PCS	Jan 12, 2026
United States	FOX04	10 PCS	Jan 12, 2026
United States	Foxo4 Dri	40 MG	Sep 15, 2025
United States	Fox04 dri	10 MT	Jun 21, 2026
United States	FOX04-DRI powder	10 MT	May 29, 2026
United States	fox04	1 G	Apr 29, 2026
United States	FOXO4-DRI	1 KG	Mar 23, 2026
United States	Foxo4-Dri	2	Nov 24, 2025
United States	FOXO4	10 PCS	Nov 15, 2025
United States	Fox04	1 G	Nov 10, 2025

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Forkhead Box O4 99%Freeze-dried powder In stock Minimum Order Hot Selling

Product Description

Seller Information

Inquiry History

Basic Parameter Information

2. Core Mechanism of Action

3. Core Research Efficacy (For Research Laboratory Use Only)

Cellular Senescence & Anti-Aging Mechanism Research

Oxidative Stress & Antioxidant Pathway Research

Glucose & Lipid Metabolic Regulation Research

Stem Cell & Tissue Regeneration Research

Apoptosis & Tumor Suppressor Signaling Study

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