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Home > Biochemical Engineering > Inhibitors > TYRA-300 for Sale > TYRA-300 CAS NO 2800223-30-5 99% high purity DIDEU white crystalline powder
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TYRA-300 CAS NO 2800223-30-5 99% high purity DIDEU white crystalline powder

TDS 149 Inquiries

Unit Price: Get Latest Price
CAS No.:

2800223-30-5

Grade:

Industrial Grade

Content:

99%

Port:

shanghai

Brand:

Dideu

Packaging:

25kg/Drum

Price valid (until):

2026-08-03

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 1


    TYRA-300 is a potent, selective, and orally active FGFR3 (fibroblast growth factor receptor 3) inhibitor. TYRA-300 can avoid toxicity associated with pan FGFR inhibitors and target key mutations in FGFR3.

    The mechanism of action of Infiglatinib is through highly selective inhibition of the activity of FGFR1, FGFR2, FGFR3, and FGFR4, acting at the biochemical and cellular levels in Chemicalbook. The activation of the FGFR pathway is associated with the proliferation of malignant cancer cells, therefore, inhibition of FGFR specific kinases can effectively reduce the proliferation of tumor cells

    BGJ398 is an effective and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinases. Bioactive BGJ398 (NVP-BGJ398) is an effective and selective FGFR inhibitor that acts on FGFR1/Chemicalbook2/3 with an IC50 of 0.9nM/1.4nM/1nM. Its selectivity towards FGFR is over 40 times higher than that towards FGFR4 and VEGFR2, and it has almost no inhibitory activity against Abl, Fyn, Kit, Lck, Lyn, and Yes.

    English synonyms
    TYRA-300;2,6-Diazaspiro[3.3]heptane,2-[5-[5-[(1R)-1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]-2-pyridinyl]-6-(methylsulfonyl)-;(R)-5-(1-(3,5-DichlorChemicalbookopyridin-4-yl)ethoxy)-3-(6-(6-(methylsulfonyl)-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-3-yl)-1H-indazole;TYRA-300(Dabogratinib);Tyra-30099%ShaanxiDideuMedichem


    Advantage
    1)Widely used for rinsing stains
    2)Active at 20 ° C
    3)Has antibacterial properties
    4)Strong deodorization effect
    5)Small amount of addition
    6)Not causing allergies
    7)Easy to use
    8)For human safety
    9)Safe for fibers and colors
    10)No VOC release
    11)Chlorine free
    12)No Seveso

    matters needing attention

    Safe storage: 4-Butylresorcinol should be stored in a dry, well ventilated environment, away from heat sources, fire sources, and open flames.

    Personal protection: Appropriate personal protective equipment such as gloves, goggles, and protective clothing should be worn during operation.

    Environmental impact: When handling 4-n-butylresorcinol, it should be avoided from entering the environment to prevent adverse effects on the environment and health.



    Item Standard Test Results
    Identification A.H-NMR:Comply with the structure Complies
    B.LC-MS:Comply with the structure Complies
    C.The IR spectrum of sample should be identical with that of reference standard. Complies
    D.HPLC-ESI-MS Complies
    The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.
    Loss on drying ≤2.0% 0.19%
    Heavy metals ≤10 ppm <10ppm
    Water ≤1.0% 0.10%
    Sulphated ash ≤0.5% determined on 1.0 g. 0.01%
    Residue on ignition ≤0.1% 0.03%
    Related Substances Unspecified impurities: for each impurity ≤0.10% <0.10%
    Total Impurity ≤0.5% 0.18%
    Purity ≥99.0% 99.70%
    Assay 99.0%~101.0% (anhydrous substance). 99.80%
    Storage Preserve in well-closed, light-resistant and airtight containers. Complies


    Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 2


    Our Services

    a) Free sample can be supplied.
    b) Guide our clients by professional knowledge and teach them how to use our product after sales.
    c) Accept SGS, BV any other third-party inspection before loading.
    d) High quality best price Guaranteed.

    Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 3

    Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 4


    Why do you choose Dideu Industries as your partner?
    A) High quality can be guaranteed. Dideu Industries since 1975 are reputed chemical manufacturer and are Certified by ISO 9001;2015 and have GMP certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P,D/A payment term. If there is any quality problem after goods arrive. Dideu Industries will do fully payment refund.
    B) Best price can be guaranteed. As Dideu Industries are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.
    C) Professional enginners from Dideu Industries will give professional usage guide and services after sales.
    D) Dideu Industries work 7×24 hours and your request will be processed by our professional staff in different shift period.


    Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 5


    Packaging and Shipping

    Our normal packaging is 25kgs/Drum and 200kgs/Drum.
    The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.

    Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 6 Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 7 Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 8 Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 9 Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 10

     Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 11

    Our company has various payment methods.

    For example: bank transfer, LC at sight,and so on.

    Shop TYRA-300 CAS NO 2800223-30-5 99%  high purity DIDEU  white crystalline powder-Detailed Image 12

    ECHEMI Editorial Reference
    Dabogratinib(TYRA-300) , a 3-pyridylindazole analog, is a reversible and selective inhibitor of FGFR3 with an IC50 of 11 nM in Ba/F3 cells. It also exhibit potent activity in human bladder cancer cell lines harboring FGFR3 activating fusions or mutations.

    Certificates

    Basic Info
    Product Name:

    TYRA-300

    Other Name:

    TYRA-300;2,6-Diazaspiro[3.3]heptane, 2-[5-[5-[(1R)-1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]-2-pyridinyl]-6-(methylsulfonyl)-;(R)-5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-3-(6-(6-(methylsulfonyl)-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-3-yl)-1H-indazole;TYRA-300(Dabogratinib);Tyra-300 99% Shaanxi Dideu Medichem

    CAS No.:

    2800223-30-5

    Molecular Formula:

    C25H24Cl2N6O3S

    InChIKeys:

    JOAFWIHZEBKYQK-OAHLLOKOSA-N

    Molecular Weight:

    559.47

    EC Number:

    610-261-8

    Categories:

    Inhibitors

    Characteristics
    Density:

    1.58±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

    Boiling Point:

    791.2±70.0 °C(predicted)

    PKA:

    11.87±0.40(predicted)

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

    Location:

    https://www.dideu.com/en/

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2016

    Certifications:

    ISO Certificate,REACH

    Company Profile
    ">Company Profile
  • Inquiry History
    149 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Tyra-300 CAS 2800223-30-5

    9 G Jul 8, 2026
    United States

    TYRA-300 CAS 2800223-30-5

    8 G Jul 14, 2026
    United States

    High Quality TYRA-300 99% powder 2800223-30-5 Shaanxi Dideu Medichem Co.Ltd

    8 G Aug 2, 2026
    Germany

    TYRA-300

    5 G Aug 1, 2026
    Canada

    TYRA 300

    1 G Jun 2, 2026
    Mexico

    Tyra-300

    12 G Aug 24, 2026
    Germany

    Tyra-300

    0.5 G Aug 24, 2026
    Egypt

    Tyra-300

    10 G Aug 23, 2026
    United States

    tyra

    1 G Aug 22, 2026
    Brazil

    Dabogratinib

    2 G Aug 14, 2026
    Canada

    tyra-300

    1 KG Aug 10, 2026
    Canada

    tyra-300/dabogratinib

    1 G Aug 9, 2026
    Poland

    Tyra-300

    15 G Aug 5, 2026
    Germany

    Tyra 300

    2 G Aug 3, 2026
    United States

    Tyra-300

    25 MG Aug 2, 2026
    Australia

    dabogratinib

    1 KG Aug 1, 2026
    United States

    Anticancer API 99% TYRA-300/TYRA 300/Dabogratinib CAS:2800223-30-5 for R&D

    6 G Jul 25, 2026
    Germany

    Dabogratinib

    1 G Jul 23, 2026
    Lithuania

    TYRA-300

    100 G Jul 21, 2026
    Canada

    Tyra-300

    10 G Jul 20, 2026
    Post an enquiry for this product
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