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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Dyclonine hydrochloride for Sale > Dyclonine Hydrochloride CAS 536-43-6 Topical Local Anesthetic and Broad-Spectrum Antimicrobial for Pharmaceutical hfd
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Dyclonine Hydrochloride CAS 536-43-6 Topical Local Anesthetic and Broad-Spectrum Antimicrobial for Pharmaceutical hfd

TDS 2 Inquiries

Unit Price:

$100-130/G FOB

Get Latest Price
CAS No.:

536-43-6

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

5g, 25g, 100g, 500g

Price valid (until):

2026-09-17

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Dyclonine Hydrochloride 4'-Butoxy-3-piperidinopropiophenone Hydrochloride
    CAS Number 536-43-6 536-43-6
    Molecular Formula C₁₈H₂₈ClNO₂ C₁₈H₂₇NO₂·HCl
    Molecular Weight 325.88 g/mol
    Appearance White to almost white crystalline powder Visual inspection 
    Purity ≥98.0% Determined by HPLC and nonaqueous titration 
    Melting Point 171.0 – 175.0°C
    Storage 0-10°C (refrigerated), heat sensitive Sealed containers, protect from heat 
    Packaging 5g, 25g, 100g, 500g Amber glass vials
    Application Research and analytical use only Topical anesthetic research, reference standard


    —— Product Detail ——

    Product Overview

    • Dyclonine Hydrochloride (CAS 536-43-6), also known as 4'-Butoxy-3-piperidinopropiophenone Hydrochloride, is a topical local anesthetic with strong mucous membrane penetration. It appears as a white to almost white crystalline powder with the molecular formula C₁₈H₂₈ClNO₂ and a molecular weight of 325.88 g/mol . The compound is characterized by a ketone structure distinct from traditional "caine" anesthetics, making it a unique agent in its class .


    Packaging & Shipping

                  • Research quantities: 5mg, 10mg, 25mg amber glass vials

                  • Bulk quantities: 50mg, 100mg amber glass bottles

                  • Custom packaging available upon request

                  • Not classified as hazardous material for transport under normal conditions

                  • Product for research and analytical use only; not for human therapeutic use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge.Target: Sodium ChannelDyclonine is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt. Dyclonine hydrochloride has been found to possess, in addition to its topical anesthetic properties, significant bactericidal and fungic
    Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.
    Dyclonine hydrochloride is a white crystalline powder possessing topical anesthetic properties characterized by rapid onset of effect, lack of systemic toxicity and a low index of sensitization.
    Dyclonine (536-43-6) is a topical anesthetic which has been used for oral and throat analgesia.1 Enhances neuronal mitochondrial function, potentiating respiration and providing protection against insults associated with neurodegenerative disorders.2 Inhibits aldehyde dehydrogenase ALDH3A1 resulting in accumulation of 4-hydroxynonenal, which renders head and neck squamous cell carcinoma cells sensitive to the cystine-glutamate antiporter inhibitor, sulfasalazine.3 Rescues frataxin deficiency in animal models as well as in buccal cells of patients with Friedreich’s Ataxia.4 Enhances the cytotoxic effect of proteasome inhibitors MG-1325 and bortezomib6 in cancer cells.
    White Crystalline Solid

    Certificates
    • Dyclonine Hydrochloride CAS 536-43-6 Topical Local Anesthetic and Broad-Spectrum Antimicrobial for Pharmaceutical hfd Certificates 1 TDS

    Basic Info
    Product Name:

    Dyclonine hydrochloride

    Other Name:

    DYCLONINE HCL;DYCLONINE HYDROCHLORIDE;LABOTEST-BB LT00771942;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HCL;1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HYDROCHLORIDE;1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanonhydrochloride;dyclonine hydrochlorideinoline-3-carboxylic acid;1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone chloride

    CAS No.:

    536-43-6

    Molecular Formula:

    C18H28ClNO2

    InChIKeys:

    KNZADIMHVBBPOA-UHFFFAOYSA-N

    Molecular Weight:

    325.87

    Exact Mass:

    325.18100

    EC Number:

    208-633-6

    UNII:

    ZEC193879Q

    NSC Number:

    756745|25588|23018

    DSSTox ID:

    DTXSID6045323

    NCI Thesaurus Code:

    C66875

    Color/Form:

    White

    HScode:

    2933399090

    Characteristics
    PSA:

    29.54000

    Melting Point:

    175-176°C

    Boiling Point:

    424.5ºC at 760 mmHg

    Flash Point:

    210.5ºC

    Water Solubility:

    Partly soluble in water. Soluble in chloroform, ethanol, acetone and methanol.

    Storage Conditions:

    -20ºC Freezer

    Collision Cross Section:

    179.6 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Critical Temperature & Pressure:

    Inert atmosphere,2-8°C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Skin irritation, Category 2

    Serious eye damage, Category 1

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H315 Causes skin irritation

    H318 Causes serious eye damage

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Australia

    Dycloninehydrochloride 90%

    10000 MT Sep 13, 2023
    Canada

    Dyclonine HCl

    100 KG Dec 13, 2023
    Post an enquiry for this product
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