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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Dyclonine for Sale > High Quality Dyclonine HCL CAS 536-43-6 Powder Fast Delivery Good Price
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High Quality Dyclonine HCL CAS 536-43-6 Powder Fast Delivery Good Price

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

536-43-6

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1kg/Bag

Price valid (until):

2025-01-17

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Name

    Dyclonine HCL

    CAS number

    536-43-6

    Synonym

    Dyclonine Hydrochloride; Dyclonine HCL; Dyclone; Dyclothane; Tanaclone;

    Description

    Dyclonine Hydrochloride is an oral local anesthetic. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade.

    Structure

    Shop High Quality Dyclonine HCL CAS 536-43-6 Powder Fast Delivery Good Price-Detailed Image 1

    Molecular Formula

    C18H28ClNO2

    Molecular Weight

    325.87 g/mol

    Appearance

    White Powder

    Quality Standard

    99%

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 2~8 for short term (days to weeks) or -20 for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag, Bottle

    Commercial package

    Aluminium Tin

    Origin

    China

    Dyclonine HCL More Info


     Dyclonine hydrochloride is a topical anesthetic that is primarily used to relieve pain and discomfort associated with various conditions affecting the mucous membranes, particularly in the oral cavity and throat. It is part of the class of local anesthetics and is effective in providing temporary numbness in the target area.

     

    Mechanism of Action

    Dyclonine functions by inhibiting sodium ion channels in nerve membranes, which prevents the conduction of nerve impulses. By blocking these signals, it effectively numbs the tissues in the application area, leading to a reduction in sensation and pain.

     

    Indications

    Dyclonine hydrochloride is indicated for various conditions, including:

     

    Sore Throat: It is commonly used to alleviate the pain associated with throat irritations.

    Oral Pain: It can be used to relieve discomfort from dental procedures, oral mucositis, or other conditions causing oral pain.

    Cough Relief: It may be included in formulations designed to soothe coughs associated with throat irritation.

    Dosage and Administration

    Dyclonine is typically available in topical forms, such as lozenges or oral solution. The recommended dosage can vary based on the specific product and formulation:

     

    Oral Lozenges: Patients may be advised to dissolve one lozenge in the mouth as needed, up to a certain number of lozenges per day, typically not exceeding a specified maximum.

    Topical Application: When used as a rinse or gargle, it may be diluted with water and used to irrigate the throat or oral cavity.

    Side Effects

    While dyclonine is generally well-tolerated, some side effects may occur, including:

     

    Local Reactions: Mild burning, stinging, or numbness in the application area.

    Dizziness: Some users may experience lightheadedness or dizziness after use.

    Allergic Reactions: Although rare, severe allergic reactions can occur and should be addressed promptly.

    Contraindications and Cautions

    Dyclonine hydrochloride should be used with caution or is contraindicated in certain populations:

     

    Hypersensitivity: Individuals with known allergies to dyclonine or other similar anesthetics should avoid its use.

    Children: Safety and efficacy in very young children have not been established; therefore, caution is advised when considering its use in this group.

    Pregnancy and Lactation: The safety of dyclonine during pregnancy and breastfeeding has not been fully established, so careful consideration is warranted.

    Clinical Considerations

    When using dyclonine, healthcare providers should:

     

    Instruct patients on the correct usage and appropriate dosage to avoid potential misuse or excessive application.

    Monitor for any adverse reactions, particularly with initial use, especially in sensitive populations.

    Educate patients on the potential side effects and the importance of avoiding food and drink immediately after use to maintain the anesthetic effect.

    In summary, dyclonine hydrochloride is an effective topical anesthetic used to relieve pain in the oral cavity and throat. Its ability to provide temporary numbness can benefit individuals suffering from sore throats, oral discomfort, and related conditions. Like all medications, it should be used with caution, and proper guidance from healthcare providers is critical for safe and effective use.


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    FAQ


    Q1. Can I get a free sample?

    We can send you a samll free sample, and you only need to pay for the shipping cost.

     

    Q2. What is the HyperChem payment term?

    T/T in advance
    LC at sight
    DP at sight

    Bank transfer

    PayPal

    Bitcoin...

     

    Q3. What is HyperChem shipment policy?

    Our policy is to strive for the quickest shipment time possible.

    For ready stock samples, they are usually shipped within 3 working days after payment received.
    For non-ready stock, please contact HyperChem sales team to negotiate.

     

    Q4. What is HyperChem shipment term?

    By Express  
    FedEx  UPS  DHL  EMS                               
    Fast: 3-7 days around, high cost, door to door service

    By Air                                        
    Suitable for more than 50kg 
    Fast: 3-7 days, hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Fast: 7-45 days, low cost, port to port, professional broker needed 

     

    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

     

    Q5. What HyperChem will provide after shipment?

    For sample orders: 
    After shipment is done, an timely email including:

    1. Track details (Fedex /TNT/DHL/EMS Track number)
    2. Packaging photo
    3. COA, MSDS, etc
    4. Dispatch date & Estimated arriving time
    5. Shipping invoice

    For commercial orders:
    A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

    Basic Info
    Product Name:

    Dyclonine

    Other Name:

    1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-,hydrochloride (1:1);Propiophenone,4′-butoxy-3-piperidino-,hydrochloride;1-Propanone,1-(4-butoxyphenyl)-3-(1-piperidinyl)-,hydrochloride;4′-Butoxy-3-piperidinopropiophenone hydrochloride;Dyclone;Dyclonine hydrochloride;Dyclonine;Diclonina;Dyclothane;Tanaclone;Dyclocaine hydrochloride;Diclonine;1-(4-Butoxyphenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride

    CAS No.:

    536-43-6

    Molecular Formula:

    C18H27NO2.ClH

    InChIKeys:

    InChIKey=KNZADIMHVBBPOA-UHFFFAOYSA-N

    Molecular Weight:

    325.87300

    Exact Mass:

    325.18100

    EC Number:

    208-633-6

    UNII:

    ZEC193879Q

    NSC Number:

    756745|25588|23018

    DSSTox ID:

    DTXSID6045323

    NCI Thesaurus Code:

    C66875

    HScode:

    2942000000

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    29.54000

    Melting Point:

    175-176 °C

    Boiling Point:

    424.5ºC at 760 mmHg

    Flash Point:

    210.5ºC

    Water Solubility:

    Partly soluble in water. Soluble in chloroform, ethanol, acetone and methanol.

    Storage Conditions:

    -20ºC Freezer

    Collision Cross Section:

    179.6 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Skin irritation, Category 2

    Serious eye damage, Category 1

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H315 Causes skin irritation

    H318 Causes serious eye damage

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Australia

    Dycloninehydrochloride 90%

    10000 MT Sep 13, 2023
    Canada

    Dyclonine HCl

    100 KG Dec 13, 2023
    Post an enquiry for this product
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