Estriol CA:50-27-1 99% High Purity Natural Estrogenic API Raw Material for Menopausal Research
TDS 3 Inquiries
50-27-1
Pharmaceutical Grade
99.9%
Hanghzou
HyperChem
1kg/bag, 5kg/bag, 25kg/Drum
2028-10-31
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceEstriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.Target: Estrogen Receptor/ERRA recent study shows that estrogen (estrone, estradiol, and estriol) inhibits Alzheimer's disease-associated low-order Aβ oligomer formation, and among them, estriol shows the strongest in vitro activity [1]. In mPTEN+/- mice, estriol treatments resulted in a 187.54% gain in the relative ratio of uterine wet weight to body weight; estriol also
Solid|Odorless white crystals.
Estriol is a 3-hydroxy steroid that is estra-1,3,5(10)-trien-3-ol substituted by additional hydroxy groups at positions 16 and 17 (16alpha,17beta-stereoisomer). It has a role as an estrogen, a human metabolite, a human xenobiotic metabolite and a mouse metabolite. It is a 3-hydroxy steroid, a 16alpha-hydroxy steroid and a 17beta-hydroxy steroid. It derives from a hydride of an estrane.|A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDA or Health Canada. It is however available in the United States by prescription filled only by compounding pharmacies. It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the treatment of post-menopausal hot flashes.|A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.CertificatesBasic Info-
Product Name:
Estriol
Other Name:Estra-1,3,5(10)-triene-3,16,17-triol,(16α,17β)-;Estriol;(16α,17β)-Estra-1,3,5(10)-triene-3,16,17-triol;Destriol;Estra-1,3,5(10)-triene-3,16α,17β-triol;Estratriol;Follicular hormone hydrate;OE3;Ovestin;Theelol;Tridestrin;3,16α,17β-Trihydroxyestra-1,3,5(10)-triene;Trihydroxyestrin;16α,17β-Estriol;3,16α,17β-Estriol;NSC 12169;16α-Estriol;16α-Hydroxyestradiol;Holin V;13β-Methyl-1,3,5(10)-gonatriene-3,16α,17β-triol;Oestriol;Colpogyn;Ortho-Gynest;Gynasan;Aacifemine;Oekolp;Triovex;Hormomed;Klimoral;Klimax E;Ovesterin;Ovo-Vinces;Incurin;Estriel;Ovestrion;1050676-52-2
CAS No.:50-27-1
Molecular Formula:C18H24O3
InChIKeys:InChIKey=PROQIPRRNZUXQM-ZXXIGWHRSA-N
Molecular Weight:288.38100
Exact Mass:288.38
EC Number:200-022-2
UNII:FB33469R8E
NSC Number:12169
DSSTox ID:DTXSID9022366
Color/Form:Leaflets from alcohol|Very small monoclinic crystals from dilute alcohol|White, microcrystalline powder
ATC Code:QG03CA04|G03CA04|G - Genito urinary system and sex hormones
HScode:29072990
Categories:
Characteristics-
PSA:
60.69000
XLogP3:2.58000
Appearance:Solid
Density:1.27 g/cm3
Melting Point:282 °C
Boiling Point:469ºC at 760 mmHg
Flash Point:220.8ºC
Refractive Index:1.624
Water Solubility:In water, 27.34 mg/L at 25 deg C (est)
Storage Conditions:-20ºC Freezer
Vapor Pressure:9.93X10-12 mm Hg at 25 deg C (est)
Toxicity:LD50 oral in rat: > 2gm/kg
Specific rotation:Specific optical rotation at D (sodium) line: +58 deg, +/-5 deg (0.04 g in 1 mL dioxane)
Odor:Odorless
Henrys Law Constant:Henry's Law constant = 1.33X10-12 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa = 10.54 (est)
Experimental Properties:During heating on the microscope heating stage, rearrangement of the crystal structure takes place at 270 °C and 275 °C (rate of heating 4 °C/min, Kofler microscope heating stage).|Precipitated by digitonin|Crystals from 90% alcohol, mp 126 °C /Estriol triacetate/
Hazard IdentificationClassification of the substance or mixture
Carcinogenicity, Category 2
Reproductive toxicity, Category 1A
Reproductive toxicity, Additional category for effects on or via lactation
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H351 Suspected of causing cancer
H360 May damage fertility or the unborn child
H362 May cause harm to breast-fed children
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy and while nursing.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Do not store above 25 deg C.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements
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Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
10
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2013
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Certifications:
Certification Report by Bureau Veritas
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Estriol
1 KG Mar 16, 2026 
Australia
estriol
90 G Feb 23, 2026
United States
Estriol
1 KG Jul 4, 2026 Post an enquiry for this product
