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Home > Agrochemicals > Pesticide Intermediates > Trifluoroacetic acid for Sale > C2hf3o2 99.5% Trifluoroacetic Acid Tfa CAS 76-05-1 Pesticide Intermediates
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C2hf3o2 99.5% Trifluoroacetic Acid Tfa CAS 76-05-1 Pesticide Intermediates

TDS 11 Inquiries

Unit Price:

$1900-2000/MT FOB

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CAS No.:

76-05-1

Grade:

Agricultural Grade

Content:

99%

Port:

qingdao

Brand:

C2hf3o2 99.5% Trifluoroacetic Acid Tfa CAS 76-05-1

Packaging:

100kg/drum

Price valid (until):

2026-10-15

Company Type:
Trader
Location:
Hongkong, China
Payment Terms:
100% TT in advance
Average Lead Time:
15 days
Qualification:
Main Products:

nitric acid,sles,xylene,aniline

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    C2hf3o2 99.5% Trifluoroacetic Acid Tfa CAS 76-05-1 Pesticide Intermediates


    Index Standard
    Appearance Colorless liquid
    Purity ≥99% (by GC)

    Properties:
    Trifluoroacetic acid (TFA) is a strong carboxylic acid with high acidity due to the electron-withdrawing effect of the trifluoromethyl group. It is highly soluble in water and most organic solvents (e.g., ethanol, ether, dichloromethane). It is corrosive and hygroscopic, requiring careful handling.

    Application:

    • Pharmaceuticals: Widely used as a solvent and reagent in peptide synthesis, drug intermediates, and protecting group removal.
    • Organic Synthesis: Effective catalyst and solvent for esterifications, acylations, and other reactions.
    • Chemical Industry: Used in the production of dyes, agrochemicals, and specialty chemicals.
    • Analytical Chemistry: Mobile phase modifier in HPLC for improved separation.

    Package and Storage:

    • Package: 180 kg/drum, or customized packaging.
    • Storage: Store in a tightly sealed container in a cool, dry, well-ventilated area. Avoid contact with moisture and incompatible materials (e.g., strong bases, oxidizers). Keep away from light.
    Items Specifications






    ECHEMI Editorial Reference
    Colorless, fuming liquid; hygroscopic; pungent odor. Very soluble in water. Nonflammable.
    Trifluoroacetic acid (TFA) is an organofluorine compound with the chemical formula CF3CO2H. It is a colorless liquid with a sharp odor similar to vinegar, but stronger in acidity. TFA is an analogue of acetic acid with the three hydrogen atoms replaced by three fluorine atoms. The acidity of TFA is approximately 34,000 times stronger than that of acetic acid due to the electronegativity of the trifluoromethyl group. TFA is widely used in organic chemistry for various purposes.
    Trifluoroacetic acid appears as a colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and as a solvent.|Liquid|FUMING COLOURLESS LIQUID WITH PUNGENT ODOUR.
    Trifluoroacetic acid appears as a colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and as a solvent.|Trifluoroacetic acid is a monocarboxylic acid that is the trifluoro derivative of acetic acid. It has a role as a reagent and a human xenobiotic metabolite. It derives from an acetic acid. It is a conjugate acid of a trifluoroacetate.|A very strong halogenated derivative of acetic acid. It is used in acid catalyzed reactions, especially those where an ester is cleaved in peptide synthesis.
    Poison by ingestion and intraperitoneal routes. Moderately toxic by intravenous route. Mildly toxic by inhalation. A corrosive irritant to skin, eyes, and mucous membranes. When heated to decomposition it emits toxic fumes of F-. Used as a strong organic acid catalyst.

    Certificates
    • C2hf3o2 99.5% Trifluoroacetic Acid Tfa CAS 76-05-1 Pesticide Intermediates Certificates 1 TDS

    Basic Info
    Product Name:

    Trifluoroacetic acid

    Other Name:

    RARECHEM AL BO 0421;PERFLUOROACETIC ACID;TRIFLUOROACETIC ACID;TRIFLUOROACETLC ACID;IPC-PFFA-2;trifluoroethanoicacid;TRIFLUOROACETETIC ACID;Trifluoroaceticacidbiolgrmincolorlessliq

    CAS No.:

    76-05-1

    Molecular Formula:

    C2HF3O2

    InChIKeys:

    DTQVDTLACAAQTR-UHFFFAOYSA-N

    Molecular Weight:

    114.02

    Exact Mass:

    114.02

    BRN:

    742035

    EC Number:

    200-929-3

    UNII:

    E5R8Z4G708

    ICSC Number:

    1673

    NSC Number:

    77366

    UN Number:

    2699

    TSCA:

    TSCA listed

    DSSTox ID:

    DTXSID9041578

    Color/Form:

    Colorless

    HScode:

    29159080

    Characteristics
    λmax:

    λ: 260 nm Amax: 0.9λ: 270 nm Amax: 0.10λ: 280 nm Amax: 0.05λ: 290 nm Amax: 0.04λ: 300 nm Amax: 0.03λ: 320 nm Amax: 0.025

    PSA:

    37.30000

    XLogP3:

    0.63330

    Appearance:

    Trifluoroacetic acid appears as a colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and as a solvent.

    Density:

    1.489 g/mL at 20 °C (lit.)

    Melting Point:

    -15.4 °C (lit.)

    Boiling Point:

    72.4 °C (lit.)

    Flash Point:

    -3ºC

    Refractive Index:

    n20/D1.3(lit.)

    Water Solubility:

    miscible

    Storage Conditions:

    2-8ºC

    Vapor Pressure:

    97.5 mm Hg ( 20 °C)

    Vapor Density:

    3.9 (vs air)

    Toxicity:

    LD50 i.v. in mice: 1200 mg/kg (Airaksinen, Tammisto)

    Odor:

    Sharp, pungent odor

    PH:

    1 (10g/l, H2O)

    PKA:

    -0.3(at 25℃)

    Henrys Law Constant:

    5.7×101mol/(m3Pa) at 25℃, Burkholder et al. (2019)

    Dissociation Constants:

    pKa = 0.3

    Experimental Properties:

    Strong, non-oxidizing acid|Hydroxyl radical reaction rate constant = 5.2X10-13 cu cm/molec-sec at 25 °C (est)

    Air and Water Reactions:

    Fumes in air. Soluble in water.

    Reactive Group:

    Acids, Carboxylic

    Reactivity Profile:

    Trifluoroacetic acid is a strong acid; attacks many metals [Handling Chemicals Safely 1980. p. 935]. A 30% solution of hydrogen peroxide in Trifluoroacetic acid is often used to destructively oxidize aromatic rings in preference to the side chains. Explosions have occurred, if the excess peroxide is not catalytically destroyed, prior to removal of solvent, [Tetrahedron Lett., 1977, 1703-1704]. The reduction of amides of Trifluoroacetic acid with lithium aluminum hydride are dangerous at all phases of the process, explosions have occurred, [Chem. Eng. News, 1955, 33, 1368].

    Physical Dangers:

    The vapour is heavier than air.

    Corrosivity:

    Corrosive

    Critical Temperature & Pressure:

    Store at +15°C to +25°C.

    Hazard Identification

    Classification of the substance or mixture

    Skin corrosion, Sub-category 1A

    Acute toxicity - Category 4, Inhalation

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H314 Causes severe skin burns and eye damage

    H332 Harmful if inhaled

    H412 Harmful to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P273 Avoid release to the environment.

    Response

    P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

    P363 Wash contaminated clothing before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO contact with bases, oxidizing agents or reducing agents. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Separated from strong bases, metals, oxidants and food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    nitric acid,sles,xylene,aniline

    Location:

    UNIT 903, 9/F., CAMERON COMM CENTRE, 458-468 HENNESSY ROAD, CAUSEWAY BAY HONG KONG

    Payment Terms:

    100% TT in advance

    Average lead Time:

    15 days

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2026

    We are a professional exporter of industrial chemical solvents and mining‑use chemicals.

    We supply a wide range of industrial solvents for coating, printing, cleaning and manufacturing industries. Our mining‑chemical products include flotation collectors, frothers, flocculants and other reagents for mineral processing and mine wastewater treatment.

    With rich experience in chemical export, we provide stable‑quality goods, customized packaging and complete export solutions. We sincerely welcome global customers for inquiries and long‑term cooperation.

  • Inquiry History
    11 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Trifluoroacetic acid

    5.00 G Mar 4, 2026
    South Korea

    Trifluoroacetic acid

    100 KG Jul 23, 2026
    Bangladesh

    trifluoroacetic acid

    15 MT Mar 10, 2026
    India

    Trifluoroacetic acid

    500 KG Apr 30, 2025
    India

    Trifluoroacetic acid

    1000.00 KG Oct 15, 2024
    United States

    Trifluoroacetic acid

    25 L May 11, 2026
    Russia

    trifluoroacetic acid

    100 L Nov 18, 2025
    Thailand

    Trifluoro acetic acid

    3 MT May 16, 2024
    India

    TRIFLUOROACETIC ACID

    5 MT Jan 5, 2024
    United States

    Trifluoroacetic acid Pharma Grade

    1 MT Sep 23, 2023
    India

    5-Bromothiophene-2-carbaldehyde

    1.00 KG May 6, 2026
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