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2-Naphthol135-19-3

Name: 2-Naphthol135-19-3
Brand: OORENT
SKU: pr2609162280
Price: 33 USD
Availability: InStock

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CAS No.:

135-19-3

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

shanghai

Brand:

OORENT

Packaging:

Vial/Bottle/Bag/Carton

Price valid (until):

2026-10-16

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

10 days

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Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
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Inquiry History

Description

Product Detail

2-Naphthol Basic information

Product Name:	2-Naphthol
Synonyms:	c.i.37500;c.i.azoiccouplingcomponent1;c.i.developer5;Developer A;Developer AMS;Developer BN;developera;developerams
CAS:	135-19-3
MF:	C10H8O
MW:	144.17
EINECS:	205-182-7
Product Categories:	Fluorescent;Naphthalene;pigments;alcohol;MICROCIDIN;Color Former & Related Compounds;Developer;Functional Materials;Intermediates;Aromatic Compounds;Alphabetical;Bioactive Small Molecules;Biochemicals and Reagents;Building Blocks;C9 to C20+;Cell Biology;Chemical Synthesis;Fluorescent Indicators and Probes;Fluorescent Probes;Labels;N;Organic Building Blocks;Oxygen Compounds;Particles and Stains;pH Sensitive Probes and Indicators;Phenols;Dyestuff Intermediates;Aromatics;135-19-3
Mol File:	135-19-3.mol

2-Naphthol Chemical Properties

Melting point	120-122 °C(lit.)
Boiling point	285-286 °C(lit.)
density	1,28 g/cm³
bulk density	300kg/m3
vapor density	4.97 (vs air)
vapor pressure	10 mm Hg ( 145.5 °C)
refractive index	1.5762 (estimate)
Fp	153 °C
storage temp.	Store below +30°C.
solubility	methanol: soluble1g/10 mL, clear, colorless to light yellow
pka	9.51(at 25℃)
form	Powder, Crystals or Granules
color	White
Odor	faint phenol-like odor
PH Range	Non& uorescence (8.5) to blue & uorescence (9.5)
Water Solubility	1 g/L (20 ºC)
Specific Heat Capacity	Cp(crystal): 1.2 J/(g·K); Cp(gas): 1.03 J/(g·K), at 25℃
λmax	226nm, 265nm, 275nm, 286nm, 320nm, 331nm
Merck	14,6384
BRN	742134
Henry's Law Constant	1.1×10² mol/(m³Pa) at 25℃, Mackay et al. (2006)
Exposure limits	PC-TWA: 0.25 mg/m3; PC-STEL: 0.5 mg/m3
Stability:	Stable. Combustible. Dust may form explosive mixture with air. Incompatible with strong oxidizing agents, phenol.
Major Application	Display device, semiconductors, photoimaging materials, inks, toner, chalk, security paper, molding materials, tin plating method, rubber, adhesive, leather, detergent, hair dyes, antimitotic drug, anticancer agent, antiinflammatory agent, treatment of acne vulgaris (pimples) and other dermal ailments (rashes, scratches, blemishes, hair loss), disorders
Cosmetics Ingredients Functions	PERFUMING HAIR DYEING
InChI	1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H
InChIKey	JWAZRIHNYRIHIV-UHFFFAOYSA-N
SMILES	Oc1ccc2ccccc2c1
LogP	1.89 at 20℃
CAS DataBase Reference	135-19-3(CAS DataBase Reference)
NIST Chemistry Reference	2-Naphthalenol(135-19-3)
EPA Substance Registry System	2-Naphthalenol (135-19-3)

Safety Information

Hazard Codes	Xn,N
Risk Statements	20/22-50
Safety Statements	24/25-61
RIDADR	UN 3077 9/PG 3
WGK Germany	2
RTECS	QL2975000
F	8
Autoignition Temperature	430 °C
TSCA	TSCA listed
HazardClass	9
PackingGroup	III
HS Code	29071590
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Inhalation Acute Tox. 4 Oral Aquatic Acute 1 Eye Dam. 1 Skin Sens. 1
Hazardous Substances Data	135-19-3(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: 1960 mg/kg LD50 dermal Rabbit > 10000 mg/kg

MSDS Information

Provider	Language
Naphthyl alcohol	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Naphthol Usage And Synthesis

Chemical Properties	2-Naphthol is a white, crystalline solid. Slight phenolic odor. Darkens in air and on exposure to light. 2-Naphthol [135-19-3] b-naphthol, 2- naphthalenol, 2-hydroxynaphthalene, C10H8O, Mr 144.16, forms colorless plates upon sublimation, which darken on exposure to air or light. Unlike 1-naphthol it is nonvolatile in steam. 2-Naphthol is reduced with sodium or with hydrogen in the presence of a catalyst to give mainly 1,2,3,4-tetrahydro-2-naphthol (unlike 1- naphthol which gives the arylphenol under the same conditions).
Physical properties	White glossy flakes or white powder. Insoluble in water, soluble in ethanol, ether, chloroform, glycerol and alkali solution.
Uses	Has been used as antiseptic, anthelmintic and counter-irritant in alopecia.
Uses	2-Naphthol is used in the manufacture of dyes, perfumes, and medicinal organics, and in the production of antioxidants for synthetic rubber.
Definition	ChEBI: 2-naphthol is a naphthol carrying a hydroxy group at position 2. It has a role as an antinematodal drug, a genotoxin, a human xenobiotic metabolite, a mouse metabolite, a human urinary metabolite and a radical scavenger.
Application	It is used to produce Tobias acid, J acid, 2-hydroxy-3-naphthoic acid and azo dyes, and it is the raw material for rubber antioxidants, mineral dressing agents, fungicides, antiseptics, preservatives, etc. As feed preservative. In China, it can be used for citrus preservation, the maximum dosage amount is 0.1 g/kg and the residue amount should be no more than 70 mg/kg. 2-Naphthol, also called β-naphthol, 2-naphthalenol, is the intermediate for plant growth regulator, 2-naphthoxyacetic acid. As analytic agent, absorbent of ethylene and carbon monoxide, and fluorescence indicator. Important organic raw material and dye intermediate, used to produce Tobias acid, butyric acid, β-hydroxynaphthoic acid and used to produce N-phenyl-2-naphthylamine, Diafen NN and other antioxidant, organic pigments, and fungicides. For the detection of bromine, chlorine, chlorate, niobium, copper, nitrite, and potassium. Substrate for fluorometric assay of phenol sulfotransferase. Acid and alkali indicator, dyes, organic synthesis, qualitative determination of allyl alcohol, methanol, chloroform, etc. Absorbent of carbon monoxide, ethanol, and fluorescence indicator. Determination of carbon monoxide, copper, nitrite, and potassium. Ethylene absorbent.
Preparation	2-Naphthol is produced by caustic fusion of naphthalene-2-sulfonic acid. Typically, the sodium salt of the sulfonic acid is added gradually to 50 % sodium hydroxide liquor at 300℃; the melt is then heated further at 320℃ in a gas-fired iron vessel with vigorous agitation. After completion of the reaction, the melt is run into excess water, possibly including filtrate from the previous batch at a proven tolerable level, and the naphtholate solution is neutralized to pH 8 with dilute sulfuric acid. If the temperature is maintained at >100℃ during neutralization, the crude product comes out of solution as an oil, which is separated, washed with hot water, and distilled under vacuum to give pure 2-naphthol. The molten material is processed through a flaker to give the final product for packaging. The fusion yield is about 80 % of the theoretical value, resulting in an overall yield of 70 % based on naphthalene. Typical specifications for 2-naphthol are clear solution in dilute caustic soda, mp 120.5℃, and 1-naphthol content<0.3 %.
Reactions	2-Naphthol is naphthalene homologues of phenol, with the hydroxyl group being more reactive than in the phenols.2-Naphthol converts to 2-naphthalenethiol by reaction with dimethylthiocarbamoyl chloride via the Newman–Kwart rearrangement.
Synthesis Reference(s)	Journal of the American Chemical Society, 72, p. 4884, 1950 DOI: 10.1021/ja01167a009 Synthesis, p. 437, 1985 DOI: 10.1055/s-1985-31235
General Description	2-Naphthol is a hydroxyarene molecule, which when electronically excited forms strong acid. Excited 2-Naphthol dissociates only in water. It has a slight phenolic odor. It is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides. It is one of the most commonly used fluorescence dye.
Health Hazard	Although the toxicity of 2-naphthol is of low order in test animals, ingestion of large amounts may result in nausea, vomiting, diarrhea, abdominal pain, convulsions, and hemolytic anemia. Death may result from respiratory failure. The oral LD50 value in rats is in the range 2000 mg/kg. 2-Naphthol is slightly more toxic than 1-naphthol [9015-3], the oral LD50 value of which is in the range 2500 mg/kg. Skin contact can produce peeling of the skin and pigmentation.
Fire Hazard	Noncombustible solid.
Chemical Reactivity	2-naphthol can be oxidation with ferric chloride forms 2,20 -dihydroxy-1,10 -binaphthyl, with any blue coloration indicating the presence of 1- naphthol. Air oxidation at 300℃ with a vanadium pentoxide catalyst also yields 1,10 -bi-2-naphthol, which dehydrates at higher temperature to the oxide and finally decomposes to give benzoic acid. 2-naphthol can reacte with phosphorus pentachloride at 150℃ gives 2-chloronaphthalene or at lower temperature, tri-2-naphthyl phosphate (mp 111℃), which can be isolated after treatment of the reaction mixture with alkali. Reaction with one equivalent of bromine in acetic acid gives 1-bromo-2-naphthol, whereas excess bromine yields 1,6-dibromo-2-naphthol. The latter is readily debrominated in dilute mineral acid to yield 6-bromo-2-naphthol.
Safety Profile	Poison by ingestion, inhalation, and subcutaneous routes. Mutation data reported. A skin and eye irritant. Combustible when exposed to heat or flame. To fight fire, use CO2, dry chemical. Incompatible with antipyrine, camphor, phenol, ferric salts, menthol, potassium permanganate and other oxidzing materials, urethane.
Potential Exposure	A potential danger to those involved in rubber antioxidant production, synthesis of dyes; leather processing; fungicides, pharmaceuticals, and perfumes. Used as an antioxidant for fats, oils; as an antiseptic; in insecticides.
Shipping	UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.
Purification Methods	Crystallise 2-naphthol from aqueous 25% EtOH (charcoal), H2O, benzene, toluene or CCl4. Alternatively, extract it repeatedly with small amounts of EtOH, followed by dissolution in a minimum volume of EtOH and precipitation with distilled water, then drying over P2O5 under vacuum. It has also been dissolved in aqueous NaOH and precipitated by adding acid (repeat several times), then precipitated from benzene by addition of heptane. Final purification can be by zone melting or sublimation in vacuo. The 4-nitrobenzoate has m 104o (from EtOH). [Bardez et al. J Phys Chem 89 5031 1985, Kikuchi et al. J Phys Chem 91 574 1987, Beilstein 6 IV 4253.]
Properties and Applications	white crystalline, with phenol smell. Industrial goods for hoar chip or powder. Melting point 121 ~ 123 ℃, 285 ℃ ~ 286 boiling point, flash point 161 ℃. This product soluble in water, ethanol, ethyl ether, chloroform, glycerin and alkali solution, can the sublimation, with steam evaporate out; Long storage or light color in turn dark, can happen oxidation, reduction, nitrification and nitrosation reaction, and products, light and heat, halogenating role, etc.
Incompatibilities	Dust or powder may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, iron salts; 2,3-dimethyl-1- phenyl-3-pyrazolin-5-one (antipyrine); camphor, phenol, menthol, urethane.
Waste Disposal	Mix with flammable solvent and atomize into an incinerator.

2-Naphthol Preparation Products And Raw materials

Raw materials

Sodium hydroxide-->Sulfuric acid-->Nitric acid-->Sodium sulfite-->Sulfur dioxide-->Naphthalene-->Congo red paper-->Naphthalene-2-sulfonic acid-->Phenolphthalein-->Sodium 2-naphthalenesulfonate

Preparation Products

2-Naphthylamine-->(R)-(+)-1,1'-Bi-2-naphthol-->Pigment Red 21-->2-Aminonaphthalene-1-sulfonic acid-->NAPROANILIDE-->(S)-(-)-1,1'-Bi-2-naphthol-->1-Amino-2-naphthol-4-sulfonic acid-->Indigo Carmine-->3-Hydroxy-2-naphthoic acid-->2-Fluoronaphthalene-->2-Acetyl-6-methoxynaphthalene-->Eriochrome Black T-->6-Hydroxy-2-naphthaleneboronic acid-->Disodium 2-naphthol-3,6-disulfonate-->1-Diazo-2-naphthol-4-sulfonic acid-->6-Amino-4-hydroxy-2-naphthalenesulfonic acid-->Lithol Red-->Pigment Red 53:1-->Pigment Orange 5-->Pigment Red 4-->Pigment Red 3-->Mordant Black 17-->Naproxen-->synthetic tanning agent HV-->Neutral Black 2S-RL-->Acid Black 168-->2-Naphthaleneboronic acid-->2-Hydroxy-1-naphthoic acid-->Sodium 6-hydroxynaphthalene-2-sulfonate-->N-(2-Naphthyl)aniline-->synthetic tanning agent PNC-->2-Amino-3,6,8-naphthalenetrisulfonic acid-->Acid blue 161, pure-->Eriochrome Black A-->synthetic tanning agent No.9

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ECHEMI Editorial Reference

2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2).

Basic Info

Product Name:

2-Naphthol

Other Name:

2-Naphthalenol;2-Naphthol;C.I. 37500;Azogen Developer A;C.I. Azoic Coupling Component 1;C.I. Developer 5;Developer A;Developer AMS;Developer BN;Developer NA;β-Hydroxynaphthalene;Isonaphthol;2-Hydroxynaphthalene;Naphthol B;β-Naphthol;Betanaphthol;β-Naphthyl alcohol;NSC 2044;NSC 5737;Bordeaux Base GP;860440-31-9

CAS No.:

135-19-3

UN No.:

3077

Molecular Formula:

C10H8O

InChIKeys:

InChIKey=JWAZRIHNYRIHIV-UHFFFAOYSA-N

Molecular Weight:

144.17000

Exact Mass:

144.17

EC Number:

205-182-7

UNII:

P2Z71CIK5H

ICSC Number:

0719

NSC Number:

758883|2044

UN Number:

3077

DSSTox ID:

DTXSID5027061

Color/Form:

White, lustrious, bulky leaflets or white powder. Darkens with age

HScode:

2907151000

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

20.23000

XLogP3:

2.7

Appearance:

DryPowder; Liquid

Density:

1.28 g/cm³ @ Temp: 20 °C

Melting Point:

121.6 °C

Boiling Point:

285 °C

Flash Point:

160ºC

Refractive Index:

1.548

Water Solubility:

H2O: 1 g/L (20 ºC)

Storage Conditions:

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store in direct sunlight. Keep container clos

Vapor Pressure:

10 mm Hg ( 145.5 °C)

Vapor Density:

4.97 (vs air)

Odor:

Faint phenol-like odor

OH:

1.70e-10 cm3/molecule*sec

Henrys Law Constant:

2.74e-08 atm-m3/mole|Henry's Law constant = 2.74X10-8 atm-cu m/mol at 25 °C

Dissociation Constants:

pKa = 9.51 at 25 °C

Experimental Properties:

Hydroxyl radical reaction rate constant= 1.70X10-10 cu cm/molec-sec at 25 °C

Autoignition Temperature:

550 °C

Physical Dangers:

Dust explosion possible if in powder or granular form, mixed with air.

See More 2-Naphthol Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Acute toxicity - Category 4, Inhalation

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H332 Harmful if inhaled H400 Very toxic to aquatic life
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P317 Get medical help. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store in an area without drain or sewer access.Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Light sensitive.

See More 2-Naphthol Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

7 Inquiries

Country	Product	Purchase Quantity	Date Posted
Thailand	β-Naphthol (2-Naphthol)	4 MT	Sep 16, 2026
India	Betanapthnol	50.00 KG	Jan 23, 2025
India	Beta naphthol	20.00 MT	Oct 9, 2023
Pakistan	Beta napthol	10000 KG	Aug 3, 2026
Nigeria	2-naphthol	1 KG	Feb 12, 2026
India	Beta Naphthol	1 20' Fcl	Jun 28, 2024
India	Beta naphthol	10.00 MT	Jan 5, 2024

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2-Naphthol135-19-3

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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